Through collaborative efforts with our partners, image data generated by the EML has been used for the covers of key publications. Below are some of the of the covers.
|Electron micrograph of wild-type Drosophila photoreceptors taken by Kunio Nagashima of the EML. Yonamine et al. demonstrate that overexpressing sphingosine kinase 2 causes photoreceptor degeneration and boosts the lysosomal degradation of light-sensing proteins such as Rhodopsin by increasing the levels of dihydrosphingosine 1 phosphate compared to sphingosine 1 phosphate. Click here for the article.|
|Dr. Ulrich Baxa, EML Director, took the cover image of Sup35p prion protein filaments visualized by negative staining electron microscopy. Globular C-domains were made visible by band-pass filtering and conversion of grey levels to color using a custom lookup table. In this paper Baxa et al. present a detailed analysis of prion filaments using negative staining, cryo-EM, and scanning transmission-EM. This shows filaments of full-length Sup35p to consists of a thin backbone fibril surrounded by a diffuse 65-nm-wide cloud of globular C-domains. Click here for the article.|