PCL Technology Development
PCL is currently focused on the following areas of technology development
- Measurement of molecular interactions using fluorescence correlation spectroscopy
- Surface capture of tagged proteins
- Thermal protein denaturation to validate small molecule-protein interaction
- Metabolic analysis of cells using the Seahorse Biosciences Flux Analyzer XF-24
- Chemical deglycolylation of N and O-glycosylated proteins
- Detergent free lysis of small amount of cells and tissue samples
- Trehalose distribution in brain using MALDI-imaging
- MALDI-imaging in combination with LET technology
- Immunoprecipiation Mass Spectrometry Assay (IPMS)
- Mass Spectrometry based Epitope mapping
Chemical deglycosylation of N,O-glycosylated and GPI-anchored proteins
