Biological Resources Branch
11B.11 MONOCLONAL ANTIBODY
Antibody Specificity: Mouse IL-4
Isotype: Rat IgG1
Buffer: 50mM Sodium Phosphate and 300mM Sodium Chloride,
pH 6.
Lot Number: L0412006
Inventory Number: 05060201
Concentration: 21.2 mg/ml, 0.27 ml/vial (total 5.7
mg/vial)
Product Storage: -70oC
- Product Testing:
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MAP:
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Cell Line Negative
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Purity by HPLC:
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> 95%
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Mycoplasma:
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Cell Line Negative
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Bioburden:
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0 CFU/ml
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Endotoxin:
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1.54 EU/mg
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Bioactivity:
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In vitro:
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0.9 ng/ml 11B.11 neutralizes 86.8% 500 pg/ml IL-4
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9.0 ng/ml 11B.11 neutralizes 96.3% 500 pg/ml IL-4
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90 ng/ml 11B.11 neutralizes >97% 500 pg/nl IL-4
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In vivo:
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5 mg of 11B.11 per week per mouse will significantly reduce endogenous IL-4 levels
in most experimental situations.
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Cell Line Origin: Dr. William Paul, NIH
References: Nature 315:33 (1985)
CAUTION: FOR RESEARCH USE ONLY. NOT FOR DRUG OR DIAGNOSTIC USE.
NOT FOR USE IN HUMANS.
11B.11 is available to investigators with peer-reviewed support, at institutions,
and at commercial establishments. Use of these materials is limited solely to in
vivo and in vitro basic research studies.
NOTE: Recipients of bulk cytokines and monoclonal antibodies will be required
to sign a Material Transfer Agreement that is auto-generated by our web program,
following the electronic submission of an order. All International requesters are
required to pay a packaging and handling fee. An invoice will be emailed for these
charges. All recipients are required to provide a FedEx account number. All recipients
are required to pay for shipping.
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