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  1. 1.   DNA fingerprinting of the NCI-60 cell line panel
  2. Lorenzi, P. L.; Reinhold, W. C.; Varma, S.; Hutchinson, A. A.; Pommier, Y.; Chanock, S. J.; Weinstein, J. N.
  3. Molecular Cancer Therapeutics. 2009 8(4): 713-724.
  1. 2.   Transcript and protein expression profiles of the NCI-60 cancer cell panel: an integromic microarray study
  2. Shankavaram, U. T.; Reinhold, W. C.; Nishizuka, S.; Major, S.; Morita, D.; Chary, K. K.; Reimers, M. A.; Scherf, U.; Kahn, A.; Dolginow, D.; Cossman, J.; Kaldjian, E. P.; Scudiero, D. A.; Petricoin, E.; Liotta, L.; Lee, J. K.; Weinstein, J. N.
  3. Molecular Cancer Therapeutics. 2007, Mar; 6(3): 820-832.
  1. 3.   Crinamine from Crinum asiaticum var.japonicum inhibits hypoxia inducible factor-1 activity but not activity of hypoxia inducible factor-2
  2. Kim, Y. H.; Park, E. J.; Park, M. H.; Badarch, U.; Woldemichael, G. M.; Beutler, J. A.
  3. Biological & Pharmaceutical Bulletin. 2006, Oct; 29(10): 2140-2142.
  1. 4.   Spectrum of activity and molecular correlates of response to phosphatidylinositol ether lipid analogues, novel lipid-based inhibitors of Akt
  2. Gills, J. J.; Holbeck, S.; Hollingshead, M.; Hewitt, S. M.; Kozikowski, A. P.; Dennis, P. A.
  3. Molecular Cancer Therapeutics. 2006, Mar; 5(3): 713-722.
  1. 5.   Cytotoxicity of RH1: NAD(P)H : quinone acceptor oxidoreductase (NQO1)-independent oxidative stress and apoptosis induction
  2. Tudor, G.; Alley, M.; Nelson, C. M.; Huang, R. L.; Covell, D. G.; Gutierrez, P.; Sausville, E. A.
  3. Anti-Cancer Drugs. 2005 16(4): 381-391.
  1. 6.   Fluorinated 2-(4-amino-3-methylphenyl) benzothiazoles induce CYP1A1 expression, become metabolized, and bind to macromolecules in sensitive human cancer cells
  2. Brantley, E.; Trapani, V.; Alley, M. C.; Hose, C. D.; Bradshaw, T. D.; Stevens, M. F. G.; Sausville, E. A.; Stinson, S. F.
  3. Drug Metabolism and Disposition. 2004, DEC; 32(12): 1392-1401.
  1. 7.   Aryl hydrocarbon receptor activation of an antitumor aminoflavone: Basis of selective toxicity for MCF-7 breast tumor cells
  2. Loaiza-Perez, A. I.; Kenney, S.; Boswell, J.; Hollingshead, M.; Alley, M. C.; Hose, C.; Ciolino, H. P.; Yeh, G. C.; Trepel, J. B.; Vistica, D. T.; Sausville, E. A.
  3. Molecular Cancer Therapeutics. 2004 3(6): 715-725.
  1. 8.   Induction of CYP1A1 in tumor cells by the antitumor agent 2-[4- amino-3-methylphenyl]-5-fluoro-benzothiazole: A potential surrogate marker for patient sensitivity
  2. Hose, C. D.; Hollingshead, M.; Sausville, E. A.; Monks, A.
  3. Molecular Cancer Therapeutics. 2003 2(12): 1265-1272.
  1. 9.   Apoptosis and melanogenesis in human melanoma cells induced by anthrax lethal factor inactivation of mitogen-activated protein kinase kinase
  2. Koo, H. M.; Vanbrocklin, M.; McWilliams, M. J.; Leppla, S. H.; Duesbery, N. S.; Vande Woude, G. F.
  3. Proceedings of the National Academy of Sciences of the United States of America. 2002 99(5): 3052-3057.
  1. 10.   Mining the National Cancer Institute's tumor-screening database: Identification of compounds with similar cellular activities
  2. Rabow, A. A.; Shoemaker, R. H.; Sausville, E. A.; Covell, D. G.
  3. Journal of Medicinal Chemistry. 2002 45(4): 818-840.
  1. 11.   P450 enzyme expression patterns in the NCI human tumor cell line panel
  2. Yu, L. J.; Matias, J.; Scudiero, D. A.; Hite, K. M.; Monks, A.; Sausville, E. A.; Waxman, D. J.
  3. Drug Metabolism and Disposition. 2001 29(3): 304-312.
  1. 12.   Characterization of MLH1 and MSH2 DNA mismatch repair proteins in cell lines of the NCI anticancer drug screen
  2. Taverna, P.; Liu, L.; Hanson, A. J.; Monks, A.; Gerson, S. L.
  3. Cancer Chemotherapy and Pharmacology. 2000 46(6): 507-516.
  1. 13.   An informatics approach identifying markers of chemosensitivity in human cancer cell lines
  2. Amundson, S. A.; Myers, T. G.; Scudiero, D.; Kitada, S.; Reed, J. C.; Fornace, A. J.
  3. Cancer Research. 2000 60(21): 6101-6110.
  1. 14.   A gene expression database for the molecular pharmacology of cancer
  2. Scherf, U.; Ross, D. T.; Waltham, M.; Smith, L. H.; Lee, J. K.; Tanabe, L.; Kohn, K. W.; Reinhold, W. C.; Myers, T. G.; Andrews, D. T.; Scudiero, D. A.; Eisen, M. B.; Sausville, E. A.; Pommier, Y.; Botstein, D.; Brown, P. O.; Weinstein, J. N.
  3. Nature Genetics. 2000 24(3): 236-244.
  1. 15.   The ras oncogene-mediated sensitization of human cells to topoisomerase II inhibitor-induced apoptosis
  2. Koo, H. M.; Gray-Goodrich, M.; Kohlhagen, G.; McWilliams, M. J.; Jeffers, M.; Vaigro-Wolff, A.; Alvord, W. G.; Monks, A.; Paull, K. D.; Pommier, Y.; Vande Woude, G. F.
  3. Journal of the National Cancer Institute. 1999 91(3): 236-244.
  1. 16.   DNA protein cross-links produced by NSC 652287, a novel thiophene derivative active against human renal cancer cells
  2. Nieves-Neira, W.; Rivera, M. I.; Kohlhagen, G.; Hursey, M. L.; Pourquier, P.; Sausville, E. A.; Pommier, Y.
  3. Molecular Pharmacology. 1999 56(3): 478-484.
  1. 17.   Selective toxicity of the tricyclic thiophene NSC652287 in renal carcinoma cell lines - Differential accumulation and metabolism
  2. Rivera, M. I.; Stinson, S. F.; Vistica, D. T.; Jorden, J. L.; Kenney, S.; Sausville, E. A.
  3. Biochemical Pharmacology. 1999 57(11): 1283-1295.
  1. 18.   Interaction of the P-glycoprotein multidrug transporter (MDR1) with high affinity peptide chemosensitizers in isolated membranes, reconstituted systems, and intact cells
  2. Sharom, F. J.; Yu, X. H.; Lu, P. H.; Liu, R. H.; Chu, J. W. K.; Szabo, K.; Muller, M.; Hose, C. D.; Monks, A.; Varadi, A.; Seprodi, J.; Sarkadi, B.
  3. Biochemical Pharmacology. 1999 58(4): 571-586.
  1. 19.   Ras oncogene-induced sensitization to 1-beta-D-arabinofuranosylcytosine
  2. Koo, H. M.; McWilliams, M. J.; Alvord, W. G.; Woude, G. F. V.
  3. Cancer Research. 1999 59(24): 6057-6062.
  1. 20.   Resistance to Paclitaxel Mediated By P-Glycoprotein Can Be Modulated By Changes in the Schedule of Administration
  2. Zhan, A. R.; Scala, S.; Monks, A.; Hose, C.; Bates, S.; Fojo, T.
  3. Cancer Chemotherapy and Pharmacology. 1997 40(3): 245-250.
  1. 21.   A Protein Expression Database For the Molecular Pharmacology of Cancer
  2. Myers, T. G.; Anderson, N. L.; Waltham, M.; Li, G.; Buolamwini, J. K.; Scudiero, D. A.; Paull, K. D.; Sausville, E. A.; Weinstein, J. N.
  3. Electrophoresis. 1997 18(3-4): 647-653.
  1. 22.   Identification of Compounds With Preferential Inhibitory Activity Against Low-Nm23-Expressing Human Breast Carcinoma and Melanoma Cell Lines
  2. Freije, J. M. P.; Lawrence, J. A.; Hollingshead, M. G.; Delarosa, A.; Narayanan, V.; Grever, M.; Sausville, E. A.; Paull, K.; Steeg, P. S.
  3. Nature Medicine. 1997 3(4): 395-401.
  1. 23.   An Information-Intensive Approach to the Molecular Pharmacology of Cancer
  2. Weinstein, J. N.; Myers, T. G.; Oconnor, P. M.; Friend, S. H.; Fornace, A. J.; Kohn, K. W.; Fojo, T.; Bates, S. E.; Rubinstein, L. V.; Anderson, N. L.; Buolamwini, J. K.; Vanosdol, W. W.; Monks, A. P.; Scudiero, D. A.; Sausville, E. A.; Zaharevitz, D. W.; Bunow, B.; Viswanadhan, V. N.; Johnson, G. S.; Wittes, R. E.; Paull, K. D.
  3. Science. 1997 275(5298): 343-349.
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