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  1. 1.   RNF219 attenuates global mRNA decay through inhibition of CCR4-NOT complex-mediated deadenylation
  2. Poetz, Fabian; Corbo,Joshua; Levdansky,Yevgen; Spiegelhalter, Alexander; Lindner, Doris; Magg, Vera; Lebedeva, Svetlana; Schweiggert, Jorg; Schott, Johanna; Valkov,Eugene; Stoecklin, Georg
  3. Nature Communications. 2021, Dec 9; 12(1):
  1. 2.   Engineering well-expressed, V2-immunofocusing HIV-1 envelope glycoprotein membrane trimers for use in heterologous prime-boost vaccine regimens
  2. Crooks, Emma T.; Almanza, Francisco; D'Addabbo, Alessio; Duggan, Erika; Zhang, Jinsong; Wagh, Kshitij; Mou, Huihui; Allen, Joel D.; Thomas, Alyssa; Osawa, Keiko; Korber, Bette T.; Tsybovsky,Yaroslav; Cale, Evan; Nolan, John; Crispin, Max; Verkoczy, Laurent K.; Binley, James M.
  3. PLoS Pathogens. 2021, Oct; 17(10):
  1. 3.   A high-resolution HLA reference panel capturing global population diversity enables multi-ancestry fine-mapping in HIV host response
  2. Luo, Yang; Kanai, Masahiro; Choi, Wanson; Li, Xinyi; Sakaue, Saori; Yamamoto, Kenichi; Ogawa, Kotaro; Gutierrez-Arcelus, Maria; Gregersen, Peter K.; Stuart, Philip E.; Elder, James T.; Forer, Lukas; Schoenherr, Sebastian; Fuchsberger, Christian; Smith, Albert V.; Fellay, Jacques; Carrington,Mary; Haas, David W.; Guo, Xiuqing; Palmer, Nicholette D.; Chen, Yii-Der Ida; Rotter, Jerome I.; Taylor, Kent D.; Rich, Stephen S.; Correa, Adolfo; Wilson, James G.; Kathiresan, Sekar; Cho, Michael H.; Metspalu, Andres; Esko, Tonu; Okada, Yukinori; Han, Buhm; McLaren, Paul J.; Raychaudhuri, Soumya
  3. Nature Genetics. 2021, Oct; 53(10): 1504-1516.
  1. 4.   Normal Mode Analysis of KRas4B Reveals Partner Specific Dynamics
  2. Eren, Meryem; Tuncbag, Nurcan; Jang,Hyunbum; Nussinov,Ruth; Gursoy, Attila; Keskin, Ozlem
  3. The journal of physical chemistry. B. 2021, May 27; 125(20): 5210-5221.
  1. 5.   Interactions of APOBEC3s with DNA and RNA
  2. Maiti, Atanu; Hou, Shurong; Schiffer, Celia A.; Matsuo,Hiroshi
  3. Current opinion in structural biology. 2021, Apr; 67: 195-204.
  1. 6.   Inhibition of Nonfunctional Ras
  2. Nussinov,Ruth; Jang, Hyunbum; Gursoy, Attila; Keskin, Ozlem; Gaponenko, Vadim
  3. Cell Chemical Biology. 2021, Feb 18; 28(2): 121-133.
  1. 7.   Structural analyses of the PKA RII beta holoenzyme containing the oncogenic DnaJB1-PKAc fusion protein reveal protomer asymmetry and fusion-induced allosteric perturbations in fibrolamellar hepatocellular carcinoma
  2. Lu, Tsan-Wen; Aoto, Phillip C.; Weng, Jui-Hung; Nielsen, Cole; Cash, Jennifer N.; Hall, James; Zhang,Ping; Simon, Sanford M.; Cianfrocco, Michael A.; Taylor, Susan S.
  3. PLOS BIOLOGY. 2020, Dec; 18(12):
  1. 8.   Membrane surface recognition by the ASAP1 PH domain and consequences for interactions with the small GTPase Arf1
  2. Soubias, Olivier; Pant, Shashank; Heinrich, Frank; Zhang,Yue; Roy, Neeladri Sekhar; Li,Jess; Jian, Xiaoying; Yohe, Marielle E; Randazzo, Paul A; Lösche, Mathias; Tajkhorshid, Emad; Byrd,Robert
  3. Science advances. 2020, Sep; 6(40): pii: eabd1882.
  1. 9.   PI3K inhibitors: review and new strategies
  2. Zhang,Mingzhen; Jang,Hyunbum; Nussinov,Ruth
  3. CHEMICAL SCIENCE. 2020, JUN 21; 11(23): 5855-5865.
  1. 10.   The generality of the GUGA MRCI approach in COLUMBUS for treating complex quantum chemistry
  2. Lischka, Hans; Shepard, Ron; Müller, Thomas; Szalay, Péter G; Pitzer, Russell M; Aquino, Adelia J A; Araújo do Nascimento, Mayzza M; Barbatti, Mario; Belcher, Lachlan T; Blaudeau, Jean-Philippe; Borges, Itamar; Brozell, Scott R; Carter, Emily A; Das, Anita; Gidofalvi, Gergely; González, Leticia; Hase, William L; Kedziora, Gary; Kertesz, Miklos; Kossoski, Fábris; Machado, Francisco B C; Matsika, Spiridoula; do Monte, Silmar A; Nachtigallová, Dana; Nieman, Reed; Oppel, Markus; Parish, Carol A; Plasser, Felix; Spada, Rene F K; Stahlberg,Eric; Ventura, Elizete; Yarkony, David R; Zhang, Zhiyong
  3. The Journal of chemical physics. 2020, Apr 07; 152(13): 134110.
  1. 11.   Unique repression domains of Pumilio utilize deadenylation and decapping factors to accelerate destruction of target mRNAs
  2. Arvola, Rene M.; Chang, Chung-Te; Buytendorp, Joseph P.; Levdansky,Yevgen; Valkov,Eugene; Freddolino, Peter L.; Goldstrohm, Aaron C.
  3. NUCLEIC ACIDS RESEARCH. 2020, Feb 28; 48: 1843-1871.
  1. 12.   High-Affinity Interactions of the nSH3/cSH3 Domains of Grb2 with the C-Terminal Proline-Rich Domain of SOS1
  2. Liao,Tsung-Jen; Jang,Hyunbum; Nussinov,Ruth; Fushman, David
  3. JOURNAL OF THE AMERICAN CHEMICAL SOCIETY. 2020, Feb 19; 142: 3401-3411.
  1. 13.   Phase separation of Polo-like kinase 4 by autoactivation and clustering drives centriole biogenesis
  2. Park, Jung-Eun; Zhang, Liang; Bang, Jeong Kyu; Andresson,Thorkell; DiMaio, Frank; Lee, Kyung S
  3. Nature communications. 2019, Oct 31; 10(1): 4959.
  1. 14.   The MLL1 trimeric catalytic complex is a dynamic conformational ensemble stabilized by multiple weak interactions
  2. Kaustov, Lilia; Lemak, Alexander; Wu, Hong; Faini, Marco; Fan,Lixin; Fang, Xianyang; Zeng, Hong; Duan, Shili; Allali-Hassani, Abdellah; Li, Fengling; Wei, Yong; Vedadi, Masoud; Aebersold, Ruedi; Wang,Yun-Xing; Houliston, Scott; Arrowsmith, Cheryl H
  3. Nucleic acids research. 2019, SEP 26; 47(17): 9433-9447.
  1. 15.   The mechanism of RNA duplex recognition and unwinding by DEAD-box helicase DDX3X
  2. Song, He; Ji,Xinhua
  3. NATURE COMMUNICATIONS. 2019, Jul 12; 10(1):
  1. 16.   Protein ensembles link genotype to phenotype
  2. Nussinov,Ruth; Tsai,Chung-Jung; Jang,Hyunbum
  3. PLoS computational biology. 2019, Jun; 15(6):
  1. 17.   Review: Precision medicine and driver mutations: Computational methods, functional assays and conformational principles for interpreting cancer drivers
  2. Nussinov,Ruth; Jang,Hyunbum; Tsai,Chung-Jung; Cheng, Feixiong
  3. PLoS computational biology. 2019, Mar; 15(3):
  1. 18.   Allosteric activation of RAF in the MAPK signaling pathway
  2. Tsai,Chung-Jung; Nussinov,Ruth
  3. CURRENT OPINION IN STRUCTURAL BIOLOGY. 2018, Dec; 53: 100-106.
  1. 19.   Hybrid Correlation Energy (HyCE): An Approach Based on Separate Evaluations of Internal and External Components
  2. Ivanic, Joseph; Schmidt, Michael W.
  3. JOURNAL OF PHYSICAL CHEMISTRY A. 2018, Jun 14; 122(23): 5223-5237.
  1. 20.   DNA binding drives the association of BRG1/hBRM bromodomains with nucleosomes
  2. Morrison, Emma A.; Sanchez, Julio C.; Ronan, Jehnna L.; Farrell, Daniel P.; Varzavand, Katayoun; Johnson, Jenna K.; Gu, Brian X.; Crabtree, Gerald R.; Musselman, Catherine A.
  3. NATURE COMMUNICATIONS. 2017, Jul 14; 8
  1. 21.   The Functional Cycle of Rnt1p: Five Consecutive Steps of Double-Stranded RNA Processing by a Eukaryotic RNase III
  2. Song, He; Fang, Xianyang; Jin, Lan; Shaw, Gary; Wang, Yun-Xing; Ji, Xinhua
  3. STRUCTURE. 2017, Feb 7; 25(2): 353-363.
  1. 22.   Oxime-based linker libraries as a general approach for the rapid generation and screening of multidentate inhibitors
  2. Bahta, M.; Liu, F.; Kim, S. E.; Stephen, A. G.; Fisher, R. J.; Burke, T. R.
  3. Nature Protocols. 2012, Apr; 7(4): 686-702.
  1. 23.   The elongation rate of RNA polymerase determines the fate of transcribed nucleosomes
  2. Bintu, L.; Kopaczynska, M.; Hodges, C.; Lubkowska, L.; Kashlev, M.; Bustamante, C.
  3. Nature Structural & Molecular Biology. 2011, Dec; 18(12): 1394-U112.
  1. 24.   Novel Substrate-Based Inhibitors of Human Glutamate Carboxypeptidase II with Enhanced Lipophilicity
  2. Plechanovova, A.; Byun, Y.; Alquicer, G.; Skultetyova, L.; Mlcochova, P.; Nemcova, A.; Kim, H. J.; Navratil, M.; Mease, R.; Lubkowski, J.; Pomper, M.; Konvalinka, J.; Rulisek, L.; Barinka, C.
  3. Journal of Medicinal Chemistry. 2011, Nov; 54(21): 7535-7546.
  1. 25.   Flexible Cullins in Cullin-RING E3 Ligases Allosterically Regulate Ubiquitination
  2. Liu, J.; Nussinov, R.
  3. Journal of Biological Chemistry. 2011, Nov; 286(47): 40934-40942.
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