Agenda

Wednesday, Apr 14 Thursday, Apr 15 Friday, Apr 16

Wednesday, April 14, 2021

09:50 am - 10:00 am EST
Welcome and Opening Remarks

Link to join

Session 1

Chair: Joana Vidigal, Ph.D., CCR

10:00 am - 10:30 am EST
Assembly of the RNA silencing complex (and beyond)

Yukihide Tomari, Ph.D.
University of Tokyo

10:30 am - 11:00 am EST
Mad about U: regulating the let7 pre-miRNA

Leemor Joshua-Tor, Ph.D.
Cold Spring Harbor

11:00 am - 11:15 am EST
BREAK

Session 2

Chair: Astrid Haase, M.D., Ph.D., NIDDK

11:15 am - 11:45 am EST
IsomiRs: How miRNAs diversify their functions via sequence modifications at the ends

Shuo Gu, Ph.D.
Center for Cancer Research, NCI

11:45 am - 12:15 pm EST
Long noncoding RNAs: hidden treasures in the cancer genome

Nadya Dimitrova, Ph.D.
Yale University

12:30 pm - 01:45 pm EST
POSTER SESSIONS AND LUNCH BREAK

Poster Session 1: RNA Therapeutics
Poster Session 2: RNA Decay
Poster Session 3: Non-Coding RNAs 1

Session 3

Chair: Colin Wu, Ph.D., CCR

01:45 pm - 02:45 pm EST
Mysteries of RNA processing by IRE1

Peter Walter, Ph.D.
University of California, San Francisco

02:45 pm - 03:00 pm EST
BREAK
03:00 pm - 03:30 pm EST
Control of protein function through localized RNA translation in dynamic cellular systems

Stavroula Mili, Ph.D.
Center for Cancer Research, NCI

03:30 pm - 04:00 pm EST
Genome regulation by long noncoding RNAs

Howard Chang, M.D., Ph.D.
Stanford University

Thursday, April 15, 2021

Session 4

Chair: Eugene Valkov, Ph.D., CCR

Link to join

10:00 am - 11:00 am EST
Initiation of translation in bacteria and eukaryotes

Venki Ramakrishnan, Ph.D.
Medical Research Council, Laboratory of Molecular Biology
Cambridge University

11:00 am - 11:15 am EST
BREAK

Session 5

Chair: Eugene Valkov, Ph.D., CCR

11:15 am - 11:45 am EST
Post-translational modification effects on phase separation to regulate RNA biology

Julie Forman-Kay, Ph.D.
Hospital for Sick Children

11:45 am - 12:15 pm EST
Mapping Protein/RNA Phase Separation in Living Cells

Clifford Brangwynne, Ph.D.
Princeton University

12:30 pm - 01:45 pm EST
POSTER SESSIONS AND LUNCH BREAK

Poster Session 4: RNA Processing
Poster Session 5: RNA Modifications 1
Poster Session 6: Non-Coding RNAs 2

Session 6

Chair: Pedro Batista, Ph.D., CCR and Natasha Caplen, Ph.D., CCR

01:45 pm - 02:15 pm EST
RNA modifications modulate function of RNA virus genomes

Cara Pager, Ph.D.
University of Albany-SUNY

02:15 pm - 02:45 pm EST
Living in the World of RNAi Therapeutics using Biomimetic Chemistry

Muthiah Manoharan, Ph.D.
Alnylam Pharmaceuticals

02:45 pm - 03:00 pm EST
BREAK
03:00 pm - 03:30 pm EST
The Convergence of Nanoscience and Nucleic Acid Medicines: New Approaches for Tracking and Treating Disease

Chad Mirkin, Ph.D.
Northwestern University

03:30 pm - 04:00 pm EST
Toward personalized microRNA therapeutics

Frank Slack, Ph.D.
Beth Israel Deaconess Medical Center

Friday, April 16, 2021

Session 7

Chair: Thomas Gonatopoulos-Pournatzis, Ph.D., CCR

Link to join

10:00 am - 10:30 am EST
The structural dynamics of the spliceosome

Holger Stark, Ph.D.
Max Planck Institute

10:30 am - 11:00 am EST
RNA in Genomic Medicine, diagnosing rare disease and COVID19 implications

Diana Baralle, M.D., MBBS
University of Southampton

11:00 am - 11:15 am EST
BREAK

Session 8

Chair: Phil Adams, Ph.D., NICHD

11:15 am - 11:45 am EST
Networks of regulatory RNAs connecting metabolism adaptation, metal homeostasis, stress responses and virulence in Staphylococcus aureus

Pascale Romby, Ph.D.
University of Strasbourg

11:45 am - 12:15 pm EST
Phase dependent CRISPR evolution

Blake Wiedenheft, Ph.D.
Montana State University

12:30 pm - 01:45 pm EST
POSTER SESSIONS AND LUNCH BREAK

Poster Session 7: Translation
Poster Session 8: RNA Modifications 2

Session 9

Chair: Katherine McJunkin, Ph.D., NIDDK and Jack Shern, M.D., CCR

 

01:45 pm - 02:45 pm EST
Distinguishing self and nonself dsRNA in vertebrates and invertebrates

Brenda Bass, Ph.D.
University of Utah

02:45 pm - 03:00 pm EST
BREAK
03:00 pm - 03:30 pm EST
The HNRNPH1-dependent maturation of the EWS-FLI1 pre-mRNA expressed in one-third of Ewing sarcomas

Natasha Caplen, Ph.D.
Center for Cancer Research, NCI

03:30 pm - 04:00 pm EST
How microRNA-target interactions direct Argonaute recycling and turnover

Joshua Mendell, M.D., Ph.D.
University of Texas, Southwestern Medical Center

04:00 pm - 04:05 pm EST
Adjourn