Agenda

09:15 am - 09:30 am EST

Welcome & Introductions

Sandra Wolin, M.D., Ph.D., Center for Cancer Research, NCI

Session I

09:30 am - 10:00 am EST

mRNA Medicine

Eckhard Jankowsky, Ph.D., Moderna

10:00 am - 10:30 am EST

A Structure-Based Approach to Drugging mRNA

Jennifer Petter, Ph.D., Arrakis Therapeutics

10:30 am - 10:45 am EST

BREAK

10:45 am - 11:15 am EST

Localized microRNAs for Mesothelioma Therapy

Chuong Hoang, M.D., Center for Cancer Research, NCI

11:15 am - 11:30 am EST

miR-590-3p Inhibits Growth of Recurrent GBM by Blocking Multiple Oncogenic Nodes

Hernando Lopez-Bertoni, Ph.D., Johns Hopkins Medicine

11:30 am - 12:00 pm EST

To the Tumor and Beyond: Tales of a Holistic miRNA Delivery Vehicle

Andrea Kasinski, Ph.D., Purdue University

12:00 pm - 01:30 pm EST

LUNCH AND POSTER SESSION

Poster Session will be in Seminar Room 110

Session II

01:30 pm - 02:00 pm EST

Chemical Engineering of Therapeutic siRNAs

Anastasia Khvorova, Ph.D., University of Massachusetts

02:00 pm - 02:15 pm EST

Utilizing RNA Devices to Control PD-1 Gene Expression in Mammalian Cells for Cancer Immunotherapy

Vibha Dwivedi, Ph.D., Center for Cancer Research, NCI

02:15 pm - 02:45 pm EST

Modulating the Conformation and Function of Disease-Relevant RNA with Small Molecules

Amanda Hargrove, Ph.D., Duke University

02:45 pm - 03:00 pm EST

BREAK

03:00 pm - 03:30 pm EST

Development and Characterization of New Precision Genome Editing Tools

Alexis Komor, Ph.D., University of California, San Diego

03:30 pm - 03:45 pm EST

Nanoparticle-Mediated Targeting of miR-181a Leads to Tumor Growth Inhibition in Pre-Clinical High Grade Serous Ovarian Cancer Model

Grace McIntyre, University of Michigan

03:45 pm - 04:15 pm EST

Editing Genomes with DNA-Dependent DNA Polymerases

Erik Sontheimer, Ph.D., University of Massachusetts

04:15 pm - 04:20 pm EST

Wrap-Up & Adjourn