Agenda

The symposium will feature our keynote speaker, Dr. Angelika Amon, Massachusetts Institute of Technology and several talks selected from submitted abstracts. 

A molecular and cell biologist, Dr. Amon is the Kathleen and Curtis Marble Professor in Cancer Research and Professor of Biology at MIT. She received her B.S. from the University of Vienna and continued her doctoral work there under Professor Kim Nasmyth at the Research Institute of Molecular Pathology, receiving her Ph.D. in 1993. She completed a two-year post-doctoral fellowship at the Whitehead Institute in Cambridge, Massachusetts and was subsequently named a Whitehead Fellow for three years. In 1999, she joined the MIT Center for Cancer Research and the Department of Biology and was promoted to full Professor in 2007. Dr. Amon has won a Presidential Early Career Award for Scientists and Engineers in 1998, was named an Associate Investigator at the Howard Hughes Medical Institute in 2000, and was the 2003 recipient of the National Science Foundation's Alan T. Waterman Award. She has also shared the 2007 Paul Marks Prize for Cancer Research and won the 2008 National Academy of Sciences Award in Molecular Biology. In 2013, Dr. Amon was awarded the Ernst Jung Prize for medicine. In 2019 she was named the recipient of the Vilcek Prize in Biomedical Science and a winner of the Breakthrough Prize in Life Sciences.

Thursday, October 31, 2019

08:50 am - 09:00 am EST
Welcome Note and Introduction about the Center of Excellence in Integrative Cancer Biology and Genomics (CEICBG) symposiums
09:00 am - 09:20 am EST
THE ROLE OF CANCER SPECIFIC LNCRNAS IN DRIVING CHROMOSOME FRAGILITY

Arun Kumar Ganesan, Laboratory of Receptor Biology and Gene Expression, Center for Cancer Research, NCI

09:20 am - 09:30 am EST
Introduction to Keynote Speaker
09:30 am - 10:30 am EST
Keynote Lecture

Role of Aneuploidy in Tumorigenesis
Angelika Amon, Ph.D.
Kathleen and Curtis Marble Professor in Cancer Research
Professor of Biology
Investigator, Howard Hughes Medical Institute
Massachusetts Institute of Technology

10:30 am - 10:40 am EST
BREAK
10:40 am - 11:00 am EST
A NOVEL ASSAY TO SCREEN SIRNA LIBRARIES IDENTIFIES PROTEIN KINASES AS REQUIRED FOR CHROMOSOME TRANSMISSION

Mikhail Liskovykh, Developmental Therapeutics Branch, Center for Cancer Research, NCI

11:00 am - 11:20 am EST
MODELING CHROMOSOME INSTABILITY IN HIGH GRADE SEROUS OVARIAN CANCER

Daniel Bronder, Cancer Genetics Branch, Center for Cancer Research, NCI

11:20 am - 11:40 am EST
HIGHER PREVALENCE OF HOMOLOGOUS RECOMBINATION DEFICIENCY IN TUMORS FROM AFRICAN AMERICANS

Sanju Sinha, Laboratory of Human Carcinogenesis, Center for Cancer Research, NCI

11:40 am - 12:00 pm EST
CHARACTERIZATION OF THE GSTM-DELETION IN RELATION TO CANCER RISK

Oscar Florez-Vargas, Laboratory of Translational Genomics, Division of Cancer Epidemiology and Genetics, NCI

12:00 pm - 12:20 pm EST
AMPLIFICATION OF A SOMATICALLY ACQUIRED ENHANCER OF THE ANDROGEN RECEPTOR DRIVES ADVANCED PROSTATE CANCER

David Takeda, Laboratory of Genitourinary Cancer Pathogenesis, Center for Cancer Research, NCI

12:20 pm - 12:40 pm EST
SINGLE CELL COPY NUMBER VARIATION ANALYSIS IN TUMOR INFILTRATING LYMPHOCYTES AND PERIPHERAL BLOOD IDENTIFIES HOTSPOTS OF GENOMIC INSTABILITY

Amanda Henning, Surgery Branch, Center for Cancer Research, NCI

12:40 pm - 12:45 pm EST
Closing Remarks