Agenda

Monday, November 4, 2019

09:15 am - 09:30 am EST
Welcome Remards

Session 1
Chair:  Natasha Caplen, Ph.D., Genetics Branch, CCR

09:30 am - 09:45 am EST
RNA BURSTING AT A SINGLE PROMOTER LEVEL IS REGULATED BY TRANSCRIPTION FACTOR MOBILITY AND HORMONE RELEASE PATTERN

Diana Stavreva, (Hager, Gordon:  LRBGE)

09:45 am - 10:00 am EST
PROFILING OF STEADY-STATE MRNA FRAGMENTATION AND EXPRESSION USING END-TO-END NANOPORE SEQUENCING

Manolis Maragkakis, (RRS)

10:00 am - 10:15 am EST
AGO-BOUND MATURE MIRNAS WITH EXPOSED 3’ ENDS ARE OLIGO-URIDYLATED BY TUTS AND SUBSEQUENTLY DEGRADED BY DIS3L2

Acong Yang, (Gu, Shuo: RBL)

10:15 am - 10:30 am EST
DESPERATELY SEEKING DICER1: MICRORNA PROCESSING GENE PREVALENCE, PENETRANCE AND PHENOTYPE

Jung Kim, (Savage, Sharon: CGB)

10:30 am - 11:30 am EST
Poster Session
11:30 am - 12:30 pm EST
Lunch
12:30 pm - 01:30 pm EST
Poster Session

Session 2
Chair: Jay Schneekloth Jr., Ph.D., Chemical Biology Laboratory, CCR

01:30 pm - 02:30 pm EST
Keynote Address

Bringing RNA Structures to Life through Functional Dynamics: Insights into Folding, Gene Regulation, and Drug Discovery
Hashim Al-Hashimi, Ph.D.
James B. Duke Professor of Biochemistry
Director, Duke Center for RNA Biology
Duke University School of Medicine

02:30 pm - 02:45 pm EST
REGULATION OF TRANSLATION INITIATION

Eugene Valkov, (RBL)

02:45 pm - 03:00 pm EST
ACETYLATION OF CYTIDINE IN 5’UTRs MODULES TRANSLATION INITIATION

Daniel Arango, (Oberdoerffer, Shalini: LRBGE)

03:00 pm - 03:15 pm EST
INVESTIGATING THE MOLECULAR AND CELLULAR ROLES OF METABOLISM ON RNA EPITRANSCRIPTOMICS IN RENAL CELL CARCINOMA.

Christina Fitzsimmons, (Batista, Pedro: LCB)

03:15 pm - 03:30 pm EST
BREAK

Session 3
Chair:  Ashish Lal, Ph.D., Genetics Branch, CCR

03:30 pm - 03:45 pm EST
PTBP1 PROMOTES ATPase-DEPENDENT DISSOCIATION OF UPF1 TO PREVENT NMD

Sarah Fritz, (Hogg, John: LRB)

03:45 pm - 04:00 pm EST
UPF1- AND STAUFEN-DEPENDENT PERINUCLEAR CEBPB MRNA DECAY SUPPRESSES C/EBPβ PHOSPHORYLATION AND ITS PRO-SENESCENCE ACTIVITY IN TUMOR CELLS

Jacqueline Salotti, (Johnson, Peter: MCGP)

04:00 pm - 04:15 pm EST
A COMMON DEEP INTRONIC MUTATION CAUSING COLLAGEN VI-RELATED MUSCULAR DYSTROPHY: VALIDATION OF SPLICE-MODULATING APPROACHES IN VITRO AND DEVELOPMENT OF A MOUSE MODEL

Veronique Bolduc, (Bonnemann, Carsten: NNDC)

04:15 pm - 04:20 pm EST
Wrap-up and Adjourn