Agenda
Understanding & Drugging RAS --Are we there yet?
Tuesday, October 8
9:00 am – 9:50 am Introduction & Welcome from
- W. Kimryn Rathmell, National Cancer Institute
- Douglas R. Lowy, National Cancer Institute
- Frank McCormick, Frederick National Lab, University of California, San Francisco
- Remarks from Terri Conneran, founder of KRAS Kickers
9:50 am – 12:10 pm Session 1: RAS Therapeutics
- Mariano Barbacid, Spanish National Cancer Research Center (CNIO)
- Andy Aguirre, Dana-Farber Cancer Institute
- Mallika Singh, Revolution Medicines
- Robert Vonderheide, University of Pennsylvania
- Ziyang Zhang, University of California, Berkeley
12:15 pm – 3:15 pm Lunch/Poster Session/Meet the Expert Sessions
3:15pm – 4:55 pm Session 2: RAS Effectors
- Dhirendra Simanshu, Frederick National Lab
- Pedro Beltran, BridgeBio Oncology Therapeutics
- Lucy Young, University of California, San Francisco
- Debbie Morrison, National Cancer Institute, Center for Cancer Research
Wednesday, October 9
9:00am – 9:30 am Special Remarks from Margaret Foti, AACR Chief Executive Officer
9:30am – 11:50 am Session 3: Biochemistry and Regulation of GTPases
- Andy Stephen, Frederick National Lab
- Brigitte Wideman, National Cancer Institute, Center for Cancer Research
- Guillermo Calero, University of Pittsburgh School of Medicine
11:50 pm – 2:45 pm Lunch/Poster Session/Meet the Expert Sessions
2:45 pm – 4:50 pm Session 4: RAS and Entangled Pathways
- Greg Jones, Pfizer
- Channing Der, University of North Carolina
- Xose Bustelo, Salamanca Cancer Research Center (CIC)
- Pau Castel, New York University, Langone Health
- Daniel Bonsor, Frederick National Lab
4:50 pm – 5:50 pm Session 5: RAS in Membranes
- Moitrayee Bhattacharyya, Yale University
- Yong Zhou, University of Texas Health Science Center
- Gaudenz Danuser, UT Southwestern
5:50 pm – 8:00 pm Networking Event
Rockwell Brewery (ticketed event, pre-payment required)
Thursday, October 10
9:00 am – 11:10 am Panel Discussion
- Mallika Singh, Revolution Medicines
- Cameron Pitt, Quanta Therapeutics
- James Christensen, Mirati
Session 6: Where are we and Next Steps
- Piro Lito, Memorial Sloan Kettering Cancer Center
- Kevan Shokat, University of California, San Francisco
11:10 am – 11:25 am RAS Symposium Wrap Up and Highlights
- Frank McCormick, Frederick National Lab, University of California, San Francisco
Pediatric Mini Symposium
11:25am – 11:45 am Introduction
11:45 am – 12:45 pm Lunch & Networking
12:45 pm – 3:00 pm Targeting RAS in Solid Tumors
- Meredith Irwin, The Hospital for Sick Children
- Sameer Agnihotri, UPMC Children’s Hospital of Pittsburgh
- Carlos Prada, Lurie Children’s Hospital
3:00 pm – 4:50 pm Targeting RAS in Hematologic Malignancies
- Nicolas Nassar, Cincinnati Children’s Hospital
- Yana Pikman, Dana-Farber Cancer Institute
- Elliot Stieglitz, UCSF Benioff Children’s Hospitals
4:50pm – 5:00 pm Concluding Remarks, Mini-Symposium Wrap Up