Agenda

Thursday, October 25, 2018

08:30 am - 08:40 am EST
Welcome (Organizers)
08:40 am - 08:45 am EST
Introduction of the CIG (Hyun Park)

Session One  (Chair Daniel Mcvicar)

08:45 am - 09:25 am EST
Luke O'Neill, Trinity College Dublin, Ireland

“Krebs Cycle reprogrammed for cytokines”

09:25 am - 09:50 am EST
Daniel Mcvicar (NCI)

Getting to NO Macrophage Metabolic Reprogramming”

09:50 am - 10:15 am EST
Iain Fraser (NIAID)

“Unbiased genetic screening uncovers a role for mitochondrial NDP kinases in inflammasome activation”

10:15 am - 10:30 am EST
Munir Akkaya (NIAID)

“Antigen stimulated B cells require a second signal to maintain their initial metabolic boost and avoid activation induced mitochondrial dysfunction”

10:30 am - 10:45 am EST

Break

Session Two (Chair Remy Bosselut)

10:45 am - 11:25 am EST
Amy Weinmann, (University of Alabama at Birmigham)

“Mechanistic connections between metabolites, epigenetics, and genome organization in T cell differentiation programs”

 

11:25 am - 11:40 am EST
Alejandro Villarino (NIAMS)

“Transcriptional programming of T cell metabolism downstream of cytokine-STAT signaling”

 

11:40 am - 12:05 pm EST
Naomi Taylor (NCI)

“Metabolite orchestration of T cell differentiation and function”

12:05 pm - 01:15 pm EST

Lunch break 

01:15 pm - 01:30 pm EST

Announcement of CIG Best Paper Awards (Melanie Vacchio)

Session Three (Chair Dragan Jankovic)

01:30 pm - 02:10 pm EST
Ed Pearce, The Max Planck Institute of Immunobiology and Epigenetics, Germany

“Metabolic compensation for self-inflicted damage during macrophage activation”
 

02:10 pm - 02:35 pm EST
Catharine Bosio (NIAID)

“IFN-g drives host metabolism to control bacterial replication independent of ROS and RNS

02:35 pm - 02:50 pm EST
Alice Amancio (NIAID)

“Is microbial-induced IL-12 production by human monocytes dependent on their metabolic status?”

02:50 pm - 03:05 pm EST

Break

Session Four (Chair Michael Fessler)

03:05 pm - 03:45 pm EST
Jonathan Powell, Johns Hopkins University School of Medicine

“Dissecting tumor metabolism from immunometabolism”

 

03:45 pm - 04:00 pm EST
Veena Somasundaram (NCI)

“Extracellular Nitric Oxide induced metabolic shifts modulate immunological responses in the tumor microenvironment

04:00 pm - 04:25 pm EST
Jonathan Lyons (NIAID)

“The growing problem of allergies: inherited metabolic defects and the atopic diathesis in humans”

04:25 pm - 04:50 pm EST
Peter J. McGuire (NHGRI)

“Immunotherapy and end-organ metabolic reprogramming”

04:50 pm - 05:00 pm EST

Closing remarks (Organizers)