Anti-Human-GD3 MoAb (R24)

Antibody Specificity: Human GD3

Isotype: Murine IgG3

Process: Hybridoma fermentation (Celltech Limited). Clinical grade/Expired.

Concentration: 2.5 mg IgG/ml

Volume: 4 ml/vial

Amount Provided: 10 mg total

Buffer: Isotonic PBS plus human serum albumin (pH 5.9)

Product Testing:
MAP: Cell Line Negative Purity by HPLC: >90%
Mycoplasma: Cell Line Negative Sterility: Pass
Endotoxin: <1 EU/ml

Product Storage: -70oC

1) Boussiotis VA, R24 anti-GD3 ganglioside antibody can induce costimulation and prevent the induction of alloantigen-specific T cell clonal anergy. Eur J Immunol 26:2149-2154, 1996
2) Houghton AN, Mouse Monoclonal IgG3 antibody detecting GD3 ganglioside: a phase I trial in patients with malignant melanoma. Proc Natl Acad Sci USA 82: 1242-1246, 1985
3) Welt S Immune and nonimmune effector functions of IgG3 mouse monoclonal antibody R24 detecting the disaloganglioside GD3 on the surface of melanoma cells. Clin Immunol Immnuopathol 45: 214-229, 1987
Address questions or comments to:

Biological Resources Branch, DCTD, DTP
ATRF, Suite E3900
P.O. Box B
Frederick, MD 21702-1201

For research use only. Not for drug or diagnostic use. NOT FOR USE IN HUMANS

Updated 11/6/2018