Skip NavigationSkip to Content
Return Return to Search Results

The Dutt1 Gene, a Novel Ncam Family Member Is Expressed in Developing Murine Neural Tissues and Has an Unusually Broad Pattern of Expression

  1. Author:
    Sundaresan, V.
    Roberts, I.
    Bateman, A.
    Bankier, A.
    Sheppard, M.
    Hobbs, C.
    Xiong, J. Y.
    Minna, J.
    Latif, F.
    Lerman, M.
    Rabbitts, P.
    1. Year: 1998
  2. Journal: Molecular & Cellular Neuroscience
    1. 11
    2. 1-2
    3. Pages: 29-35
  4. Type of Article: Article
  1. Abstract:

    A new member of the NCAM family mapping to 3p12 has been isolated and predicted to be arranged in five immunoglobulin-like domains and three fibronectin-like domains which are particularly homologous to L1. There is a transmembrane domain and a long cytoplasmic region with no detectable homology to other sequences. Although less closely related to DCC, another family member, both share a loop of positively charged amino acids within the first immunoglobulin domain, unique to these two members of this very large gene family. Preliminary studies of expression in mouse embryos support an inferred role in neural development, but the observation of widespread gene expression in adult human tissues indicates that this protein has additional functions to those performed in neural cells. [References: 31]

    See More

  1. Keywords:

External Sources

  1. No sources found.

Library Notes

  1. No notes added.
NCI at Frederick

You are leaving a government website.

This external link provides additional information that is consistent with the intended purpose of this site. The government cannot attest to the accuracy of a non-federal site.

Linking to a non-federal site does not constitute an endorsement by this institution or any of its employees of the sponsors or the information and products presented on the site. You will be subject to the destination site's privacy policy when you follow the link.

ContinueCancel