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  1. 1.   Distinct allosteric networks in CDK4 and CDK6 in the cell cycle and in drug resistance
  2. Zhang,Wengang; Bradburn, Devin; Heidebrink, Gretchen; Liu, Yonglan; Jang,Hyunbum; Nussinov,Ruth; Kõivomägi, Mardo
  3. Journal of Molecular Biology. 2025, Mar 31; 169121.
  1. 2.   Slower CDK4 and faster CDK2 activation in the cell cycle
  2. Zhang,Wengang; Liu,Yonglan; Jang,Hyunbum; Nussinov,Ruth
  3. Structure (London, England : 1993). 2024, Apr 23;
  1. 3.   Plant Natural Products in Anticancer Drug Discovery
  2. Grothaus, P. G.; Cragg, G. M.; Newman, D. J.
  3. Current Organic Chemistry. 2010, Oct; 14(16): 1781-1791.
  1. 4.   A dual role of Cdk2 in DNA damage response
  2. Satyanarayana, A.; Kaldis, P.
  3. Cell Division. 2009, May; 4: 4.
  1. 5.   Rb/Cdk2/Cdk4 triple mutant mice elicit an alternative mechanism for regulation of the G(1)/S transition
  2. Li, W.; Kotoshiba, S.; Berthet, C.; Hilton, M. B.; Kaldis, P.
  3. Proceedings of the National Academy of Sciences of the United States of America. 2009 106(2): 486-491.
  1. 6.   Mammalian cell-cycle regulation: several Cdks, numerous cyclins and diverse compensatory mechanisms
  2. Satyanarayana, A.; Kaldis, P.
  3. Oncogene. 2009 28(33): 2925-2939.
  1. 7.   Id1 immortalizes hematopoietic progenitors in vitro and promotes a myeloproliferative disease in vivo
  2. Suh, H. C.; Leeanansaksiri, W.; Ji, M.; Klarmann, K. D.; Renn, K.; Gooya, J.; Smith, D.; McNiece, I.; Lugthart, S.; Valk, P. J.; Delwel, R.; Keller, J. R.
  3. Oncogene. 2008, Sep 18; 27(42): 5612-5623.
  1. 8.   Genetic substitution of Cdk1 by Cdk2 leads to embryonic lethality and loss of meiotic function of Cdk2
  2. Satyanarayana, A.; Berthet, C.; Lopez-Molina, J.; Coppola, V.; Tessarollo, L.; Kaldis, P.
  3. Development. 2008 135(20): 3389-3400.
  1. 9.   p21 inhibits Cdk1 in the absence of Cdk2 to maintain the G1/S phase DNA damage checkpoint
  2. Satyanarayana, A.; Hilton, M. B.; Kaldis, P.
  3. Molecular Biology of the Cell. 2008 19(1): 65-77.
  1. 10.   Natural products from marine invertebrates and microbes as modulators of antitumor targets
  2. Newman, D. J.; Cragg, G. M.
  3. Current Drug Targets. 2006, MAR; 7(3): 279-304.
  1. 11.   Cell cycle sibling rivalry - Cdc2 vs. Cdk2
  2. Kaldis, P.; Aleem, E.
  3. Cell Cycle. 2005, NOV; 4(11): 1491-1494.
  1. 12.   Cytokine-driven cell cycling is mediated through Cdc25A
  2. Khaled, A. R.; Bulavin, D. V.; Kittipatarin, C.; Li, W. Q.; Alvarez, M.; Kim, K.; Young, H. A.; Fornace, A. J.; Durum, S. K.
  3. Journal of Cell Biology. 2005, JUN 6; 169(5): 755-763.
  1. 13.   Homology model of the CDK1/cyclin B complex
  2. McGrath, C. F.; Pattabiraman, N.; Kellogg, G. E.; Lemcke, T.; Kunick, C.; Sausville, E. A.; Zaharevitz, D. W.; Gussio, R.
  3. Journal of Biomolecular Structure & Dynamics. 2005, APR; 22(5): 493-502.
  1. 14.   The N-terminal peptide of the Kaposi's sarcoma-associated herpesvirus (KSHV)-cyclin determines substrate specificity
  2. Kaldis, P.
  3. Journal of Biological Chemistry. 2005, MAR 25; 280(12): 11165-11174.
  1. 15.   The search for novel drug leads for predominately antitumor therapies by utilizing mother nature's pharmacophoric libraries
  2. Kingston, D. G. I.; Newman, D. J.
  3. Current Opinion in Drug Discovery & Development. 2005, MAR; 8(2): 207-227.
  1. 16.   Cdk2 knockout mice are viable
  2. Berthet, C.; Aleem, E.; Coppola, V.; Tessarollo, L.; Kaldis, P.
  3. Current Biology. 2003 13(20): 1775-1785.
  1. 17.   Plants as a source of anti-cancer and anti-HIV agents
  2. Cragg, G. M.; Newman, D. J.
  3. Annals of Applied Biology. 2003 143(2): 127-133.
  1. 18.   INK4a-deficient human diploid fibroblasts are resistant to RAS- induced senescence
  2. Brookes, S.; Rowe, J.; Ruas, M.; Llanos, S.; Clark, P. A.; Lomax, M.; James, M. C.; Vatcheva, R.; Bates, S.; Vousden, K. H.; Parry, D.; Gruis, N.; Smit, N.; Bergman, W.; Peters, G.
  3. Embo Journal. 2002 21(12): 2936-2945.
  1. 19.   The effects of changing the site of activating phosphorylation in CDK2 from threonine to serine
  2. Kaldis, P.; Cheng, A. Y.; Solomon, M. J.
  3. Journal of Biological Chemistry. 2000 275(42): 32578-32584.
  1. 20.   The influence of natural products upon drug discovery
  2. Newman, D. J.; Cragg, G. M.; Snader, K. M.
  3. Natural Product Reports. 2000 17(3): 215-234.
  1. 21.   Human papillomavirus and cancer: The viral transforming genes
  2. Phillips, A. C.; Vousden, K. H.; Newton, R.; Beral, V.; Weiss, R. A.
  3. Infections and Human Cancer. 1999; 33 : 55-74.
  1. 22.   Mechanisms of p53-mediated apoptosis
  2. Bates, S.; Vousden, K. H.
  3. Cellular and Molecular Life Sciences. 1999 55(1): 28-37.
  1. 23.   Flavopiridol Induces Apoptosis of Normal Lymphoid Cells, Causes Immunosuppression, and Has Potent Antitumor Activity in Vivo Against Human Leukemia and Lymphoma Xenografts
  2. Arguello, F.; Alexander, M.; Sterry, J. A.; Tudor, G.; Smith, E. M.; Kalavar, N. T.; Greene, J. F.; Koss, W.; Morgan, C. D.; Stinson, S. F.; Siford, T. J.; Alvord, W. G.; Klabansky, R. L.; Sausville, E. A.
  3. Blood. 1998 91(7): 2482-2490.
  1. 24.   Overexpression of P21(Waf1/Cip1) Arrests the Growth of Chicken Embryo Fibroblasts That Overexpress E2f1
  2. Givol, I.; Givol, D.; Hughes, S. H.
  3. Oncogene. 1998 16(24): 3115-3122.
  1. 25.   Association of Cdk2/Cyclin E and Nf-Kappa-B Complexes At G1/S Phase
  2. Chen, E. Y.; Li, C. C. H.
  3. Biochemical and Biophysical Research Communications. 1998 249(3): 728-734.
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