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  1. 1.   Improved Production of Class I Phosphatidylinositol 4,5-bisphosphate 3-kinase
  2. Messing,Simon; Widmeyer, Stephanie R T; Denson,John-Paul; Mehalko,Jennifer; Wall,Vanessa; Drew,Matt; Snead,Kelly; Hong,Min; Grose,Carissa; Esposito,Dom; Gillette,Bill
  3. Protein Expression and Purification. 2024, Aug 20; 106582.
  1. 2.   Calmodulin (CaM) Activates PI3K alpha by Targeting the "Soft" CaM-Binding Motifs in Both the nSH2 and cSH2 Domains of p85 alpha
  2. Zhang,Mingzhen; Li, Zhigang; Wang, Guanqiao; Jang,Hyunbum; Sacks, David B.; Zhang, Jian; Gaponenko, Vadim; Nussinov,Ruth
  3. JOURNAL OF PHYSICAL CHEMISTRY B. 2018, Dec 13; 122(49): 11137-11146.
  1. 3.   Interaction of Calmodulin with the cSH2 Domain of the p85 Regulatory Subunit
  2. Wang, Guanqiao; Zhang, Mingzhen; Jang, Hyunbum; Lu, Shaoyong; Lin, Shizhou; Chen, Guoqiang; Nussinov, Ruth; Zhang, Jian; Gaponenko, Vadim
  3. Biochemistry. 2018, Mar 27; 57(12): 1917-1928.
  1. 4.   Role of Phosphatidylinositol 3-Kinase in Friend Spleen Focus-Forming Virus-Induced Erythroid Disease
  2. Umehara, D.; Watanabe, S.; Ochi, H.; Anai, Y.; Ahmed, N.; Kannagi, M.; Hanson, C.; Ruscetti, S.; Nishigaki, K.
  3. Journal of Virology. 2010, Aug; 84(15): 7675-7682.
  1. 5.   Interaction between the human immunodeficiency virus type 1 Gag matrix domain and phosphatidylinositol-(4,5)-bisphosphate is essential for efficient Gag membrane binding
  2. Chukkapalli, V.; Hogue, I. B.; Boyko, V.; Hu, W. S.; Ono, A.
  3. Journal of Virology. 2008 82(5): 2405-2417.
  1. 6.   Constitutive activation of Akt contributes to the pathogenesis and survival of mantle cell lymphoma
  2. Rudelius, M.; Pittaluga, S.; Nishizuka, S.; Pham, T. H. T.; Fend, F.; Jaffe, E. S.; Quintanilla-Martinez, L.; Raffeld, M.
  3. Blood. 2006, Sep; 108(5): 1668-1676.
  1. 7.   Protein kinase C zeta is required for epidermal growth factor-induced chemotaxis of human breast cancer cells
  2. Sun, R. H.; Gao, P.; Chen, L.; Ma, D. L.; Wang, J. M.; Oppenheim, J. J.; Zhang, N.
  3. Cancer Research. 2005, FEB 15; 65(4): 1433-1441.
  1. 8.   Wortmannin, a widely used phosphoinositide 3-kinase inhibitor, also potently inhibits mammalian polo-like kinase
  2. Liu, Y. S.; Shreder, K. R.; Gai, W. Z.; Corral, S.; Ferris, D. K.; Rosenblum, J. S.
  3. Chemistry & Biology. 2005, JAN; 12(1): 99-107.
  1. 9.   Crosstalk between BCR/ABL oncoprotein and CXCR4 signaling through a Src family kinase in human leukemia cells
  2. Ptasznik, A.; Urbanowska, E.; Chinta, S.; Costa, M. A.; Katz, B. A.; Stanislaus, M. A.; Demir, G.; Linnekin, D.; Pan, Z. K.; Gewirtz, A. M.
  3. Journal of Experimental Medicine. 2002 196(5): 667-678.
  1. 10.   Human dendritic cells express functional formyl peptide receptor-like-2 (FPRL2) throughout maturation
  2. Yang, D.; Chen, Q.; Gertz, B.; He, R.; Phulsuksombati, M.; Ye, R. D.; Oppenheim, J. J.
  3. Journal of Leukocyte Biology. 2002 72(3): 598-607.
  1. 11.   Receptors for chemotactic formyl peptides as pharmacological targets
  2. Le, Y. Y.; Yang, Y. M.; Cui, Y. H.; Yazawa, H.; Gong, W. H.; Qiu, C. P.; Wang, J. M.
  3. International Immunopharmacology. 2002 2(1): 1-13.
  1. 13.   Synthetic peptide MMK-1 is a highly specific chemotactic agonist for leukocyte FPRL1
  2. Hu, J. Y.; Le, Y. Y.; Gong, W. H.; Dunlop, N. M.; Gao, J. L.; Murphy, P. M.; Wang, J. M.
  3. Journal of Leukocyte Biology. 2001 70(1): 155-161.
  1. 14.   The synthetic peptide Trp-Lys-Tyr-Met-Val-D-Met is a potent chemotactic agonist for mouse formyl peptide receptor
  2. He, R.; Tan, L.; Browning, D. D.; Wang, J. M.; Ye, R. D.
  3. Journal of Immunology. 2000 165(8): 4598-4605.
  1. 15.   cDNA cloning and mapping of mouse pleckstrin (Plek), a gene upregulated in transformation-resistant cells
  2. Cmarik, J. L.; Hegamyer, G.; Gerrard, B.; Dean, M.; Colburn, N. H.
  3. Genomics. 2000 66(2): 204-212.
  1. 16.   The selective and inducible activation of endogenous PI 3-kinase in PC12 cells results in efficient NGF-mediated survival but defective neurite outgrowth
  2. Ashcroft, M.; Stephens, R. M.; Hallberg, B.; Downward, J.; Kaplan, D. R.
  3. Oncogene. 1999 18(32): 4586-4597.
  1. 17.   Macrophage stimulating protein-induced epithelial cell adhesion is mediated by a PI3-K-dependent, but FAK-independent mechanism
  2. Danilkovitch, A.; Skeel, A.; Leonard, E. J.
  3. Experimental Cell Research. 1999 248(2): 575-582.
  1. 18.   Utilization of two seven-transmembrane, G protein-coupled receptors, formyl peptide receptor-like 1 and formyl peptide receptor, by the synthetic hexapeptide WKYMVm for human phagocyte activation
  2. Le, Y. Y.; Gong, W. H.; Li, B. Q.; Dunlop, N. M.; Shen, W. P.; Su, S. B.; Ye, R. D.; Wang, J. M.
  3. Journal of Immunology. 1999 163(12): 6777-6784.
  1. 19.   Direct Regulation of the Akt Proto-Oncogene Product By Phosphatidylinosital-3,4-Bisphosphate
  2. Franke, T. F.; Kaplan, D. R.; Cantley, L. C.; Toker, A.
  3. Science. 1997 275(5300): 665-668.
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