Platinum Publications, January 1–March 31, 2016

denotes Platinum Highlight article. Click on the image to go to the Platinum Highlight article. 

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AIDS RESEARCH AND HUMAN RETROVIRUSES  

Del Prete GQ, Smedley J, Macallister R, Jones GS, Li B, Hattersley J, Zheng J, Piatak M, Keele BF, Hesselgesser J, Geleziunas R, Lifson JD. Short Communication: Comparative Evaluation of Coformulated Injectable Combination Antiretroviral Therapy Regimens in Simian Immunodeficiency Virus-Infected Rhesus Macaques. AIDS Res Hum Retroviruses 32(2):163-168, 2016.

 

 

 

 

BLOOD  

Donahue RE, Srinivasula S, Uchida N, Kim I, Claire AS, Duralde G, DeGrange P, Claire MS, Reba RC, Bonifacino AC, Krouse AE, Metzger ME, Paik CH, Lane HC, Tisdale JF, Di Mascio M. Discordance in lymphoid tissue recovery following stem cell transplantation in rhesus macaques: an in vivo imaging study. Blood 126(24):2632-2641, 2015.

 

 

 

 

CANCER RESEARCH

Cook JA, Chandramouli GV, Anver MR, Sowers AL, Thetford A, Krausz KW, Gonzalez FJ, Mitchell JB, Patterson AD. Mass Spectrometry-based Metabolomics Identifies Longitudinal Urinary Metabolite Profiles Predictive of Radiation-induced Cancer. Cancer Res 2016.
[Epub ahead of print] - This article is not yet available in the print journal.

Nagarsheth N, Peng DJ, Kryczek I, Wu K, Li W, Zhao ED, Zhao LL, Wei S, Frankel T, Vatan L, Szeliga W, Dou YL, Owens S, Marquez V, Tao KX, Huang E, Wang GB, Zou WP. PRC2 Epigenetically Silences Th1-Type Chemokines to Suppress Effector T-Cell Trafficking in Colon Cancer. Cancer Res 76(2):275-282, 2016.

Prueitt RL, Wallace TA, Glynn SA, Yi M, Tang W, Luo J, Dorsey TH, Stagliano KE, Gillespie JW, Hudson RS, Terunuma A, Shoe JL, Haines DC, Yfantis HG, Han M, Martin DN, Jordan SV, Borin JF, Naslund MJ, Alexander RB, Stephens RM, Loffredo CA, Lee DH, Putluri N, Sreekumar A, Hurwitz AA, Ambs S. An Immune-Inflammation Gene Expression Signature in Prostate Tumors of Smokers. Cancer Res 2015.
[Epub ahead of print] - This article is not yet available in the print journal.

 

 

 

 

FASEB JOURNAL  

Jang H, Banerjee A, Chavan TS, Lu S, Zhang J, Gaponenko V, Nussinov R. The higher level of complexity of K-Ras4B activation at the membrane. FASEB J 2015.
[Epub ahead of print] - This article is not yet available in the print journal.

 

 

 

 

HUMAN MOLECULAR GENETICS  

Thirthagiri E, Klarmann KD, Shukla AK, Southon E, Biswas K, Martin BK, North SL, Magidson V, Burkett S, Haines DC, Noer K, Matthai R, Tessarollo L, Loncarek J, Keller JR, Sharan SK. BRCA2 minor transcript lacking exons 4-7 supports viability in mice and may account for survival of humans with a pathogenic biallelic mutation. Hum Mol Genet 2016.
[Epub ahead of print] - This article is not yet available in the print journal.

 

 

 

 

JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY  

Happel CS, Stone KD, Freeman AF, Shah NN, Wang A, Lyons JJ, Guerrerio PA, Hickstein DD, Su HC. Food allergies can persist after myeloablative hematopoietic stem cell transplantation in dedicator of cytokinesis 8-deficient patients. J Allergy Clin Immunol 2016.
[Epub ahead of print] - This article is not yet available in the print journal.

Hox V, O'Connell MP, Lyons JJ, Sackstein P, Dimaggio T, Jones N, Nelson C, Boehm M, Holland SM, Freeman AF, Tweardy DJ, Olivera A, Metcalfe DD, Milner JD. Diminution of signal transducer and activator of transcription 3 signaling inhibits vascular permeability and anaphylaxis. J Allergy Clin Immunol 2016.
[Epub ahead of print] - This article is not yet available in the print journal.

 

 

 

 

JOURNAL OF BIOLOGICAL CHEMISTRY  

Caropreso V, Darvishi E, Turbyville TJ, Ratnayake R, Grohar PJ, McMahon JB, Woldemichael G. Englerin A inhibits EWS-FLI1 DNA Binding in Ewings Sarcoma Cells. J Biol Chem 2016.
[Epub ahead of print] - This article is not yet available in the print journal.

Li SJ, Liang YH, Mariano J, Metzger MB, Stringer DK, Hristova VA, Li J, Randazzo PA, Tsai YC, Ji XH, Weissman AM. Insights into Ubiquitination from the Unique Clamp-like Binding of the RING E3 AO7 to the E2 UbcH5B. J Biol Chem 290(51):30225-30239, 2015.

Sharma NR, Wang XH, Majerciak V, Ajiro M, Kruhlak M, Meyers C, Zheng ZM. Cell Type- and Tissue Context-dependent Nuclear Distribution of Human Ago2. J Biol Chem 291(5):2302-2309, 2016.

Woodfolk JA, Glesner J, Wright PW, Kepley CL, Li M, Himly M, Muehling LM, Gustchina A, Wlodawer A, Chapman MD, Pomes A. Antigenic Determinants of the Bilobal Cockroach Allergen Bla g 2. J Biol Chem 291(5):2288-2301, 2016.

 

 

 

 

JOURNAL OF CELL BIOLOGY  

Magidson V, He J, Ault JG, O'Connell CB, Yang NC, Tikhonenko I, McEwen BF, Sui HX, Khodjakov A. Unattached kinetochores rather than intrakinetochore tension arrest mitosis in taxol-treated cells. J Cell Biol 212(3):307-319, 2016.

 

 

 

 

JOURNAL OF CLINICAL INVESTIGATION  

Maldarelli F. The role of HIV integration in viral persistence: no more whistling past the proviral graveyard. J Clin Invest 126(2):438-447, 2016.

Yu HY, Artomov M, Brahler S, Stander MC, Shamsan G, Sampson MG, White JM, Kretzler M, Miner JH, Jain S, Winkler CA, Mitra RD, Kopp JB, Daly MJ, Shaw AS. A role for genetic susceptibility in sporadic focal segmental glomerulosclerosis. J Clin Invest 126(3):1067-1078, 2016.

 

 

 

 

JOURNAL OF CLINICAL ONCOLOGY  

Brudno JN, Somerville RP, Shi V, Rose JJ, Halverson DC, Fowler DH, Gea-Banacloche JC, Pavletic SZ, Hickstein DD, Lu TL, Feldman SA, Iwamoto AT, Kurlander R, Maric I, Goy A, Hansen BG, Wilder JS, Blacklock-Schuver B, Hakim FT, Rosenberg SA, Gress RE, Kochenderfer JN. Allogeneic T Cells That Express an Anti-CD19 Chimeric Antigen Receptor Induce Remissions of B-Cell Malignancies That Progress After Allogeneic Hematopoietic Stem-Cell Transplantation Without Causing Graft-Versus-Host Disease. J Clin Oncol 2016.
[Epub ahead of print] - This article is not yet available in the print journal.

 

 

 

 

JOURNAL OF IMMUNOLOGY  

Lee-Chang C, Bodogai M, Moritoh K, Chen X, Wersto R, Sen R, Young HA, Croft M, Ferrucci L, Biragyn A. Aging Converts Innate B1a Cells into Potent CD8+ T Cell Inducers. J Immunol 2016.
[Epub ahead of print] - This article is not yet available in the print journal.

Manuzak JA, Hensley-McBain T, Zevin AS, Miller C, Cubas R, Agricola B, Gile J, Richert-Spuhler L, Patilea G, Estes JD, Langevin S, Reeves RK, Haddad EK, Klatt NR. Enhancement of Microbiota in Healthy Macaques Results in Beneficial Modulation of Mucosal and Systemic Immune Function. J Immunol 196(5):2401-9, 2016.

Zeng M, Smith AJ, Shang L, Wietgrefe SW, Voss JE, Carlis JV, Li Q, Piatak M, Jr., Lifson JD, Johnson RP, Haase AT. Mucosal Humoral Immune Response to SIVmac239nef Vaccination and Vaginal Challenge. J Immunol 2016.
[Epub ahead of print] - This article is not yet available in the print journal.

 

 

 

 

JOURNAL OF INFECTIOUS DISEASES  

Dodd LE, Proschan MA, Neuhaus J, Koopmeiners JS, Neaton J, Beigel JD, Barrett K, Lane HC, Davey RT, Jr. Design of a Randomized Controlled Trial for Ebola Virus Disease Medical Countermeasures: PREVAIL II, the Ebola MCM Study. J Infect Dis 2016.
[Epub ahead of print] - This article is not yet available in the print journal.

Houser KV, Gretebeck L, Ying T, Wang Y, Vogel L, Lamirande EW, Bock K, Moore IN, Dimitrov DS, Subbarao K. Prophylaxis with a MERS-CoV-specific human monoclonal antibody protects rabbits from MERS-CoV infection. J Infect Dis 2016.
[Epub ahead of print] - This article is not yet available in the print journal.

 

 

 

 

JOURNAL OF MEDICINAL CHEMISTRY  

Ranade AR, Higgins L, Markowski TW, Glaser N, Kashin D, Bai R, Hong KH, Hamel E, Hofle G, Georg GI. Characterizing the Epothilone Binding Site on beta-Tubulin by Photoaffinity Labeling: Identification of beta-Tubulin Peptides TARGSQQY and TSRGSQQY as Targets of an Epothilone Photoprobe for Polymerized Tubulin. J Med Chem 2016.
[Epub ahead of print] - This article is not yet available in the print journal.

 

 

 

 

JOURNAL OF THE NATIONAL CANCER INSTITUTE  

Han Y, Rand KA, Hazelett DJ, Ingles SA, Kittles RA, Strom SS, Rybicki BA, Nemesure B, Isaacs WB, Stanford JL, Zheng W, Schumacher FR, Berndt SI, Wang Z, Xu J, Rohland N, Reich D, Tandon A, Pasaniuc B, Allen A, Quinque D, Mallick S, Notani D, Rosenfeld MG, Jayani RS, Kolb S, Gapstur SM, Stevens VL, Pettaway CA, Yeboah ED, Tettey Y, Biritwum RB, Adjei AA, Tay E, Truelove A, Niwa S, Chokkalingam AP, John EM, Murphy AB, Signorello LB, Carpten J, Leske MC, Wu SY, Hennis AJ, Neslund-Dudas C, Hsing AW, Chu L, Goodman PJ, Klein EA, Zheng SL, Witte JS, Casey G, Lubwama A, Pooler LC, Sheng X, Coetzee GA, Cook MB, Chanock SJ, Stram DO, Watya S, Blot WJ, Conti DV, Henderson BE, Haiman CA. Prostate Cancer Susceptibility in Men of African Ancestry at 8q24. J Natl Cancer Inst 108(7), 2016.

Lih CJ, Chen AP. N of 2 Responders with LMNA-NTRK1. J Natl Cancer Inst 108(1), 2016.

 

 

 

 

JOURNAL OF VIROLOGY  

Barros M, Heinrich F, Datta SA, Rein A, Karageorgos I, Nanda H, Losche M. Membrane Binding of HIV-1 MA Protein: Dependence on Bilayer Composition and Protein Lipidation. J Virol 2016.
[Epub ahead of print] - This article is not yet available in the print journal.

Bolton DL, Pegu A, Wang KY, McGinnis K, Nason M, Foulds K, Letukas V, Schmidt SD, Chen XJ, Todd JP, Lifson JD, Rao S, Michael NL, Robb ML, Mascola JR, Koup RA. Human Immunodeficiency Virus Type 1 Monoclonal Antibodies Suppress Acute Simian-Human Immunodeficiency Virus Viremia and Limit Seeding of Cell-Associated Viral Reservoirs. J Virol 90(3):1321-1332, 2016.

Swanstrom AE, Haggarty B, Jordan AP, Romano J, Leslie GJ, Aye PP, Marx PA, Lackner AA, Del Prete GQ, Robinson JE, Betts MR, Montefiori DC, LaBranche CC, Hoxie JA. Derivation and characterization of a CD4-independent, non-CD4 tropic simian immunodeficiency virus. J Virol 2016.
[Epub ahead of print] - This article is not yet available in the print journal.

 

 

 

 

METHODS IN MOLECULAR BIOLOGY  

Rausch JW, Sztuba-Solinska J, Lusvarghi S, Le Grice SF. Novel Biochemical Tools for Probing HIV RNA Structure. Methods Mol Biol 1354:91-117, 2016.

Wang Z, Jensen MA, Zenklusen JC. A Practical Guide to The Cancer Genome Atlas (TCGA). Methods Mol Biol 1418:111-41, 2016.

Whiteaker JR, Halusa GN, Hoofnagle AN, Sharma V, MacLean B, Yan P, Wrobel JA, Kennedy J, Mani DR, Zimmerman LJ, Meyer MR, Mesri M, Boja E, Carr SA, Chan DW, Chen X, Chen J, Davies SR, Ellis MJ, Fenyo D, Hiltke T, Ketchum KA, Kinsinger C, Kuhn E, Liebler DC, Liu T, Loss M, MacCoss MJ, Qian WJ, Rivers R, Rodland KD, Ruggles KV, Scott MG, Smith RD, Thomas S, Townsend RR, Whiteley G, Wu C, Zhang H, Zhang Z, Rodriguez H, Paulovich AG. Using the CPTAC Assay Portal to Identify and Implement Highly Characterized Targeted Proteomics Assays. Methods Mol Biol 1410:223-36, 2016

 

 

 

 

NATURE  

Ma C, Kesarwala AH, Eggert T, Medina-Echeverz J, Kleiner DE, Jin P, Stroncek DF, Terabe M, Kapoor V, ElGindi M, Han M, Thornton AM, Zhang H, Egger M, Luo J, Felsher DW, McVicar DW, Weber A, Heikenwalder M, Greten TF. NAFLD causes selective CD4(+) T lymphocyte loss and promotes hepatocarcinogenesis. Nature 531(7593):253-7, 2016.

 

 

 

 

NATURE MEDICINE  

Zaragoza B, Chen X, Oppenheim JJ, Baeyens A, Gregoire S, Chader D, Gorochov G, Miyara M, Salomon BL. Suppressive activity of human regulatory T cells is maintained in the presence of TNF. Nat Med 22(1):16-7, 2016.

 

NEW ENGLAND JOURNAL OF MEDICINE  

Boyden SE, Desai A, Cruse G, Young ML, Bolan HC, Scott LM, Eisch AR, Long RD, Lee CC, Satorius CL, Pakstis AJ, Olivera A, Mullikin JC, Chouery E, Megarbane A, Medlej-Hashim M, Kidd KK, Kastner DL, Metcalfe DD, Komarow HD. Vibratory Urticaria Associated with a Missense Variant in ADGRE2. N Engl J Med 374(7):656-63, 2016.

 

 

 

 

PLOS GENETICS  

An P, Penugonda S, Thorball CW, Bartha I, Goedert JJ, Donfield S, Buchbinder S, Binns-Roemer E, Kirk GD, Zhang W, Fellay J, Yu XF, Winkler CA. Role of APOBEC3F Gene Variation in HIV-1 Disease Progression and Pneumocystis Pneumonia. PLoS Genetics 12(3):e1005921, 2016.

 

 

 

 

PLOS ONE  

Andersen NJ, Boguslawski EA, Naidu AS, Szot C, Bromberg-White JL, Kits K, Kuk CY, Holton LE, St Croix B, Chambers CM, Duesbery NS. Anthrax Toxin Receptor 1 Is Essential for Arteriogenesis in a Mouse Model of Hindlimb Ischemia. PLoS One 11(1):e0146586, 2016.

Corona A, Meleddu R, Esposito F, Distinto S, Bianco G, Masaoka T, Maccioni E, Menendez-Arias L, Alcaro S, Le Grice SF, Tramontano E. Ribonuclease H/DNA Polymerase HIV-1 Reverse Transcriptase Dual Inhibitor: Mechanistic Studies on the Allosteric Mode of Action of Isatin-Based Compound RMNC6. PLoS One 11(1):e0147225, 2016.

Ramena G, Yin Y, Yu Y, Walia V, Elble RC. CLCA2 Interactor EVA1 Is Required for Mammary Epithelial Cell Differentiation. PLoS One 11(3):e0147489, 2016.

Schmid T, Blees JS, Bajer MM, Wild J, Pescatori L, Cuzzucoli Crucitti G, Scipione L, Costi R, Henrich CJ, Brune B, Colburn NH, Di Santo R. Diaryl Disulfides as Novel Stabilizers of Tumor Suppressor Pdcd4. PLoS One 11(3):e0151643, 2016.

Sorber R, Teper Y, Abisoye-Ogunniyan A, Waterfall JJ, Davis S, Killian JK, Pineda M, Ray S, McCord MR, Pflicke H, Burkett SS, Meltzer PS, Rudloff U. Whole Genome Sequencing of Newly Established Pancreatic Cancer Lines Identifies Novel Somatic Mutation (c.2587G>A) in Axon Guidance Receptor Plexin A1 as Enhancer of Proliferation and Invasion. PLoS One 11(3):e0149833, 2016.

 

 

 

 

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES  

Chen JB, Rahman SA, Nikolaitchik OA, Grunwald D, Sardo L, Burdick RC, Plisov S, Liang E, Tai S, Pathak VK, Hu WS. HIV-1 RNA genome dimerizes on the plasma membrane in the presence of Gag protein. Proc Natl Acad Sci U S A 113(2):E201-E208, 2016.

Ju W, Zhang M, Wilson KM, Petrus MN, Bamford RN, Zhang X, Guha R, Ferrer M, Thomas CJ, Waldmann TA. Augmented efficacy of brentuximab vedotin combined with ruxolitinib and/or Navitoclax in a murine model of human Hodgkin's lymphoma. Proc Natl Acad Sci U S A 113(6):1624-9, 2016.

Kennedy MW, Chalamalasetty RB, Thomas S, Garriock RJ, Jailwala P, Yamaguchi TP. Sp5 and Sp8 recruit beta-catenin and Tcf1-Lef1 to select enhancers to activate Wnt target gene transcription. Proc Natl Acad Sci U S A 2016.
[Epub ahead of print] - This article is not yet available in the print journal.

Simonetti FR, Sobolewski MD, Fyne E, Shao W, Spindler J, Hattori J, Anderson EM, Watters SA, Hill S, Wu X, Wells D, Su L, Luke BT, Halvas EK, Besson G, Penrose KJ, Yang Z, Kwan RW, Van Waes C, Uldrick T, Citrin DE, Kovacs J, Polis MA, Rehm CA, Gorelick R, Piatak M, Keele BF, Kearney MF, Coffin JM, Hughes SH, Mellors JW, Maldarelli F. Clonally expanded CD4+ T cells can produce infectious HIV-1 in vivo. Proc Natl Acad Sci U S A 113(7):1883-8, 2016.

Zhu J, Kwan KM, Mackem S. Putative oncogene Brachyury (T) is essential to specify cell fate but dispensable for notochord progenitor proliferation and EMT. Proc Natl Acad Sci U S A 2016.
[Epub ahead of print] - This article is not yet available in the print journal.

 

 

 

 

RETROVIROLOGY  

Smith SJ, Pauly GT, Akram A, Melody K, Rai G, Maloney DJ, Ambrose Z, Thomas CJ, Schneider JT, Hughes SH. Rilpivirine analogs potently inhibit drug-resistant HIV-1 mutants. Retrovirology 13(1):11, 2016.

 

 

 

 

SCIENCE  

Banerjee S, Bartesaghi A, Merk A, Rao P, Bulfer SL, Yan Y, Green N, Mroczkowski B, Neitz RJ, Wipf P, Falconieri V, Deshaies RJ, Milne JL, Huryn D, Arkin M, Subramaniam S. 2.3 A resolution cryo-EM structure of human p97 and mechanism of allosteric inhibition. Science 351(6275):871-5, 2016.

Misasi J, Gilman MS, Kanekiyo M, Gui M, Cagigi A, Mulangu S, Corti D, Ledgerwood JE, Lanzavecchia A, Cunningham J, Muyembe-Tamfun JJ, Baxa U, Graham BS, Xiang Y, Sullivan NJ, McLellan JS. Structural and molecular basis for Ebola virus neutralization by protective human antibodies. Science 351(6279):1343-6, 2016.

Shi Y, Chen X, Elsasser S, Stocks BB, Tian G, Lee BH, Shi Y, Zhang N, de Poot SA, Tuebing F, Sun S, Vannoy J, Tarasov SG, Engen JR, Finley D, Walters KJ. Rpn1 provides adjacent receptor sites for substrate binding and deubiquitination by the proteasome. Science 351(6275):2016.

 

 

 

 

VIROLOGY  

Ayala VI, Trivett MT, Coren LV, Jain S, Bohn PS, Wiseman RW, O'Connor DH, Ohlen C, Ott DE. A novel SIV gag-specific CD4T-cell clone suppresses SIV replication in CD4T cells revealing the interplay between antiviral effector cells and their infected targets. Virology 493:100-112, 2016.

Johnson RF, Bagci U, Keith L, Tang X, Mollura DJ, Zeitlin L, Qin J, Huzella L, Bartos CJ, Bohorova N, Bohorov O, Goodman C, Kim do H, Paulty MH, Velasco J, Whaley KJ, Johnson JC, Pettitt J, Ork BL, Solomon J, Oberlander N, Zhu Q, Sun J, Holbrook MR, Olinger GG, Baric RS, Hensley LE, Jahrling PB, Marasco WA. 3B11-N, a monoclonal antibody against MERS-CoV, reduces lung pathology in rhesus monkeys following intratracheal inoculation of MERS-CoV Jordan-n3/2012. Virology 490:49-58, 2016.