Platinum Publications are selected from articles by NCI at Frederick scientists published in 42 prestigious science journals. This list represents articles published during the time period shown above, as generated from PubMed.
Articles designated as Platinum Highlights are noteworthy articles selected by Dr. Craig Reynolds, associate director, National Cancer Institute, from among the most recently published Platinum Publications.
The Scientific Library maintains the NCI at Frederick-in-Print database, a collection of citations for journal articles authored by NCI at Frederick employees since 1997.
denotes Platinum Highlight article. Click on the image to go to the Platinum Highlight article.
BLOOD
Cui Y, Onozawa M, Garber HR, Samsel L, Wang Z, McCoy JP, Burkett S, Wu X, Aplan PD, Mackall CL. Thymic expression of a T cell receptor targeting a tumor associated antigen co-expressed in the thymus induces T-ALL. Blood 125(19):2958-2967, 2015.
Lynn RC, Poussin M, Kalota A, Feng Y, Low PS, Dimitrov DS, Powell DJ, Jr. Targeting of folate receptor-beta on acute myeloid leukemia blasts with chimeric antigen receptor expressing T cells. Blood 2015. [Epub ahead of print - This article is not yet available in the print journal.]
CARCINOGENESIS
Seow WJ, Zhang L, Vermeulen R, Tang X, Hu W, Bassig BA, Ji Z, Shiels MS, Kemp TJ, Shen M, Qiu C, Reiss B, Beane Freeman L, Blair A, Kim C, Guo W, Wen C, Li L, Pinto LA, Huang H, Smith MT, Hildesheim A, Rothman N, Lan Q. Circulating immune/inflammation markers in Chinese workers occupationally exposed to formaldehyde. Carcinogenesis 2015. [Epub ahead of print - This article is not yet available in the print journal.]
JOURNAL OF BIOLOGICAL CHEMISTRY
Ithychanda SS, Fang XY, Mohan ML, Zhu L, Tirupula KC, Prasad SVN, Wang YX, Karnik SS, Qin J. A Mechanism of Global Shape-dependent Recognition and phosphorylation of filamin by protein kinase A. J Biol Chem 290(13):8527-8538, 2015.
Park CH, Park JE, Kim TS, Kang YH, Soung NK, Zhou M, Kim NH, Bang JK, Lee KS. Mammalian Polo-like Kinase 1 (Plk1) Promotes proper chromosome segregation by phosphorylating and delocalizing the PBIP1.CENP-Q complex from kinetochores. J Biol Chem 290(13):8569-8581, 2015.
JOURNAL OF CLINICAL ONCOLOGY
Conlon KC, Lugli E, Welles HC, Rosenberg SA, Fojo AT, Morris JC, Fleisher TA, Dubois SP, Perera LP, Stewart DM, Goldman CK, Bryant BR, Decker JM, Chen J, Worthy TA, Figg WD, Peer CJ, Sneller MC, Lane HC, Yovandich JL, Creekmore SP, Roederer M, Waldmann TA. Redistribution, Hyperproliferation, Activation of Natural Killer Cells and CD8 T Cells, and Cytokine Production During First-in-Human Clinical Trial of Recombinant Human Interleukin-15 in Patients With Cancer. J Clin Oncol 33(1):74-82, 2015.
JOURNAL OF IMMUNOLOGY
Montezuma-Rusca JM, Moir S, Kardava L, Buckner CM, Louie A, Kim LJY, Santich BH, Wang W, Fankuchen OR, Diaz G, Daub JR, Rosenzweig SD, Chun TW, Li YX, Braylan RC, Calvo KR, Fauci AS. Bone marrow plasma cells are a primary source of serum HIV-1-specific antibodies in chronically infected individuals. J Immunol 194(6):2561-2568, 2015.
Wang J, Shirota Y, Bayik D, Shirota H, Tross D, Gulley JL, Wood LV, Berzofsky JA, Klinman DM. Effect of TLR agonists on the differentiation and function of human monocytic myeloid-derived suppressor cells. J Immunol 194(9):4215-21, 2015.
JOURNAL OF INFECTIOUS DISEASES
Estes JD, Reilly C, Trubey CM, Fletcher CV, Cory TJ, Piatak M, Russ S, Anderson J, Reimann TG, Star R, Smith A, Tracy RP, Berglund A, Schmidt T, Coalter V, Chertova E, Smedley J, Haase AT, Lifson JD, Schacker TW. Antifibrotic Therapy in simian immunodeficiency virus infection preserves CD4(+) T-cell populations and improves immune reconstitution with antiretroviral therapy. J Infect Dis 211(5):744-754, 2015.
Polizzotto MN, Millo C, Uldrick TS, Aleman K, Whatley M, Wyvill KM, O'Mahony D, Marshall V, Whitby D, Maass-Moreno R, Steinberg SM, Little RF, Yarchoan R. 18F-fluorodeoxyglucose positron emission tomography in kaposi sarcoma herpesvirus-associated multicentric castleman disease: correlation with activity, severity, inflammatory and virologic parameters. J Infect Dis 2015. [Epub ahead of print - This article is not yet available in the print journal.]
JOURNAL OF MEDICINAL CHEMISTRY
Beck DE, Abdelmalak M, Lv W, Reddy PV, Tender GS, O'Neill E, Agama K, Marchand C, Pommier Y, Cushman M. Discovery of potent indenoisoquinoline topoisomerase i poisons lacking the 3-nitro toxicophore. J Med Chem 2015. [Epub ahead of print - This article is not yet available in the print journal.]
Nakagawa-Goto K, Oda A, Hamel E, Ohkoshi E, Lee KH, Goto M. Development of a novel class of tubulin inhibitor from desmosdumotin B with a hydroxylated bicyclic B-ring. J Med Chem 58(5):2378-2389, 2015.
JOURNAL OF MOLECULAR BIOLOGY
Lungu C, Muegge K, Jeltsch A, Jurkowska RZ. An ATPase-deficient variant of the SNF2 family member HELLS Shows altered dynamics at pericentromeric heterochromatin. J Mol Biol 427(10):1903-15, 2015.
Tedbury PR, Mercredi PY, Gaines CR, Summers MF, Freed EO. Elucidating the mechanism by which compensatory mutations rescue an hiv-1 matrix mutant defective for gag membrane targeting and envelope glycoprotein incorporation. J Mol Biol 427(6 Pt. B):1413-1427, 2015.
JOURNAL OF THE AMERICAN CHEMICAL SOCIETY
Chan ST, Patel PR, Ransom TR, Henrich CJ, McKee TC, Goey AK, Cook KM, Figg WD, McMahon JB, Schnermann MJ, Gustafson KR. Structural elucidation and synthesis of eudistidine A: an unusual polycyclic marine alkaloid that blocks interaction of the protein binding domains of p300 and HIF-1alpha. J Am Chem Soc 137(16):5569-75, 2015.
JOURNAL OF THE NATIONAL CANCER INSTITUTE
Mirabello L, Yeager M, Mai PL, Gastier-Foster JM, Gorlick R, Khanna C, Patino-Garcia A, Sierrasesumaga L, Lecanda F, Andrulis IL, Wunder JS, Gokgoz N, Barkauskas DA, Zhang X, Vogt A, Jones K, Boland JF, Chanock SJ, Savage SA. Germline TP53 variants and susceptibility to osteosarcoma. J Natl Cancer Inst 107(7):2015.
JOURNAL OF VIROLOGY
Hulot SL, Korber B, Giorgi EE, Vandergrift N, Saunders KO, Balachandran H, Mach LV, Lifton MA, Pantaleo G, Tartaglia J, Phogat S, Jacobs B, Kibler K, Perdiguero B, Gomez CE, Esteban M, Rosati M, Felber BK, Pavlakis GN, Parks R, Lloyd K, Sutherland L, Scearce R, Letvin NL, Seaman MS, Alam SM, Montefiori D, Liao HX, Haynes BF, Santra S. Comparison of immunogenicity in rhesus macaques of transmitted-founder, HIV-1 group M consensus and trivalent mosaic Envelope vaccines formulated as a DNA prime, NYVAC and Envelope protein boost. J Virol 2015. [Epub ahead of print - This article is not yet available in the print journal.]
Jain S, Trivett MT, Ayala VI, Ohlen C, Ott DE. African green monkey TRIM5 alpha restriction in simian immunodeficiency virus-specific rhesus macaque effector CD4 T cells enhances their survival and antiviral function. J Virol 89(8):4449-4456, 2015.
Mackelprang RD, Carrington M, Thomas KK, Hughes JP, Baeten JM, Wald A, Farquhar C, Fife K, Campbell MS, Kapiga S, Gao XJ, Mullins JI, Lingappa JR. Host genetic and viral determinants of hiV-1 RNA set point among HIV-1 seroconverters from sub-Saharan Africa. J Virol 89(4):2104-2111, 2015.
Majerciak V, Pripuzova N, Chan C, Temkin N, Specht SI, Zheng ZM. Stability of structured Kaposi's sarcoma-associated herpesvirus ORF57 protein is regulated by protein phosphorylation and homodimerization. J Virol 89(6):3256-3274, 2015.
Schafer JL, Li H, Evans TI, Estes JD, Reeves RK. Accumulation of cytotoxic CD16+ NK Cells in SIV-infected lymph nodes associated with in situ differentiation and functional anergy. J Virol 2015. [Epub ahead of print - This article is not yet available in the print journal.]
LANCET
Kohli A, Osinusi A, Sims Z, Nelson A, Meissner EG, Barrett LL, Bon D, Marti MM, Silk R, Kotb C, Gross C, Jolley TA, Sidharthan S, Petersen T, Townsend K, Egerson D, Kapoor R, Spurlin E, Sneller M, Proschan M, Herrmann E, Kwan R, Teferi G, Talwani R, Diaz G, Kleiner DE, Wood BJ, Chavez J, Abbott S, Symonds WT, Subramanian GM, Pang PS, McHutchison J, Polis MA, Fauci AS, Masur H, Kottilil S. Virological response after 6 week triple-drug regimens for hepatitis C: a proof-of-concept phase 2A cohort study. Lancet 385(9973):1107-1113, 2015.
METHODS IN MOLECULAR BIOLOGY
Afonin KA, Schultz D, Jaeger L, Gwinn E, Shapiro BA. Silver nanoclusters for RNA nanotechnology: steps towards visualization and tracking of RNA nanoparticle assemblies. Methods Mol Biol 129759-66, 2015.
MOLECULAR AND CELLULAR BIOLOGY
Tsukiyama T, Fukui A, Terai S, Fujioka Y, Shinada K, Takahashi H, Yamaguchi TP, Ohba Y, Hatakeyama S. Molecular role of RNF43 in canonical and noncanonical Wnt signaling. Mol Cell Biol 35(11):2007-23, 2015.
NATURE
Caskey M, Klein F, Lorenzi JC, Seaman MS, West AP, Jr., Buckley N, Kremer G, Nogueira L, Braunschweig M, Scheid JF, Horwitz JA, Shimeliovich I, Ben-Avraham S, Witmer-Pack M, Platten M, Lehmann C, Burke LA, Hawthorne T, Gorelick RJ, Walker BD, Keler T, Gulick RM, Fatkenheuer G, Schlesinger SJ, Nussenzweig MC. Viraemia suppressed in HIV-1-infected humans by broadly neutralizing antibody 3BNC117. Nature 2015. [Epub ahead of print - This article is not yet available in the print journal.]
Fillmore CM, Xu CX, Desai PT, Berry JM, Rowbotham SP, Lin YJ, Zhang HK, Marquez VE, Hammerman PS, Wong KK, Kim CF. EZH2 inhibition sensitizes BRG1 and EGFR mutant lung tumours to TopoII inhibitors. Nature 520(7546):239-U261, 2015.
Turner TN, Sharma K, Oh EC, Liu YFP, Collins RL, Sosa MX, Auer DR, Brand H, Sanders SJ, Moreno-De-Luca D, Pihur V, Plona T, Pike K, Soppet DR, Smith MW, Cheung SW, Martin CL, State MW, Talkowski ME, Cook E, Huganir R, Katsanis N, Chakravarti A. Loss of delta-catenin function in severe autism. Nature 520(7545):51-56, 2015.
NATURE IMMUNOLOGY
Pobezinsky LA, Etzensperger R, Jeurling S, Alag A, Kadakia T, McCaughtry TM, Kimura MY, Sharrow SO, Guinter TI, Feigenbaum L, Singer A. Let-7 microRNAs target the lineage-specific transcription factor PLZF to regulate terminal NKT cell differentiation and effector function. Nat Immunol 16(5):517-24, 2015.
NEW ENGLAND JOURNAL OF MEDICINE
Regules JA, Beigel JH, Paolino KM, Voell J, Castellano AR, Munoz P, Moon JE, Ruck RC, Bennett JW, Twomey PS, Gutierrez RL, Remich SA, Hack HR, Wisniewski ML, Josleyn MD, Kwilas SA, Van Deusen N, Mbaya OT, Zhou Y, Stanley DA, Bliss RL, Cebrik D, Smith KS, Shi M, Ledgerwood JE, Graham BS, Sullivan NJ, Jagodzinski LL, Peel SA, Alimonti JB, Hooper JW, Silvera PM, Martin BK, Monath TP, Ramsey WJ, Link CJ, Lane HC, Michael NL, Davey RT, Jr., Thomas SJ, Group r-Z-GS. A recombinant vesicular stomatitis virus ebola vaccine - preliminary report. N Engl J Med 2015. [Epub ahead of print - This article is not yet available in the print journal.]
NUCLEIC ACIDS RESEARCH
Ren JK, Briones V, Barbour S, Yu WS, Han YX, Terashima M, Muegge K. The ATP binding site of the chromatin remodeling homolog Lsh is required for nucleosome density and de novo DNA methylation at repeat sequences. Nucleic Acids Res 43(3):1444-1455, 2015.
Sherpa C, Rausch JW, SF JLG, Hammarskjold ML, Rekosh D. The HIV-1 Rev response element (RRE) adopts alternative conformations that promote different rates of virus replication. Nucleic Acids Res 2015. [Epub ahead of print - This article is not yet available in the print journal.]
PLOS COMPUTATIONAL BIOLOGY
Cui Q, Nussinov R. Making biomolecular simulations accessible in the post-Nobel Prize era. PLoS Comput Biol 10(8):e1003786, 2014.
PLOS ONE
Fedorova EV, Buryakina AV, Zakharov AV, Filimonov DA, Lagunin AA, Poroikov VV. Design, synthesis and pharmacological evaluation of novel vanadium-containing complexes as antidiabetic agents. PLoS One 9(7):e100386, 2014.
Huang BL, Mackem S. Tamoxifen-dependent, inducible Bmp2CreER drives selective recombinase activity in early interdigital mesenchyme and digit collateral ligaments. PLoS One 10(4):e0123325, 2015.
Jain M, Zhang L, Boufraqech M, Liu-Chittenden Y, Bussey K, Demeure MJ, Wu X, Su L, Pacak K, Stratakis CA, Kebebew E. ZNF367 inhibits cancer progression and is targeted by miR-195. PLoS One 9(7):e101423, 2014.
Monjazeb AM, Tietze JK, Grossenbacher SK, Hsiao HH, Zamora AE, Mirsoian A, Koehn B, Blazar BR, Weiss JM, Wiltrout RH, Sckisel GD, Murphy WJ. Bystander activation and anti-tumor effects of CD8+ T cells following Interleukin-2 based immunotherapy is independent of CD4+ T cell help. PLoS One 9(8):e102709, 2014.
Muthana SM, Xia L, Campbell CT, Zhang YL, Gildersleeve JC. Competition between serum IgG, IgM, and IgA anti-glycan antibodies. PLoS One 10(3):e0119298, 2015.
Rausch JW, Tian M, Li Y, Angelova L, Bagaya BS, Krebs KC, Qian F, Zhu C, Arts EJ, Le Grice SF, Gao Y. SiRNA-induced mutation in HIV-1 polypurine tract region and its influence on viral fitness. PLoS One 10(4):e0122953, 2015.
Sayers KT, Brooks AD, Sayers TJ, Chertov O. Increased secretory leukocyte protease inhibitor (SLPI) production by highly metastatic mouse breast cancer cells. PLoS One 9(8):e104223, 2014.
Soulas C, Autissier PJ, Burdo TH, Piatak M, Jr., Lifson JD, Williams KC. Distinct phenotype, longitudinal changes of numbers and cell-associated virus in blood dendritic cells in SIV-infected CD8-lymphocyte depleted macaques. PLoS One 10(4):e0119764, 2015.
Stansell E, Panico M, Canis K, Pang PC, Bouche L, Binet D, O'Connor MJ, Chertova E, Bess J, Lifson JD, Haslam SM, Morris HR, Desrosiers RC, Dell A. Gp120 on HIV-1 virions lacks O-linked carbohydrate. PLoS One 10(4):e0124784, 2015.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES
Fouts TR, Bagley K, Prado IJ, Bobb KL, Schwartz JA, Xu R, Zagursky RJ, Egan MA, Eldridge JH, LaBranche CC, Montefiori DC, Le Buanec H, Zagury D, Pal R, Pavlakis GN, Felber BK, Franchini G, Gordon S, Vaccari M, Lewis GK, DeVico AL, Gallo RC. Balance of cellular and humoral immunity determines the level of protection by HIV vaccines in rhesus macaque models of HIV infection. Proc Natl Acad Sci U S A 112(9):E992-E999, 2015.
Penno C, Sharma V, Coakley A, O'Connell Motherway M, van Sinderen D, Lubkowska L, Kireeva ML, Kashlev M, Baranov PV, Atkins JF. Productive mRNA stem loop-mediated transcriptional slippage: crucial features in common with intrinsic terminators. Proc Natl Acad Sci U S A 112(16):E1984-93, 2015.