Agenda

 

Draft agenda, possibly subject to change.  

Monday, May 13, 2024

08:30 am - 09:15 am EST
Session 1: Welcome and Opening Keynote Lecture

Session chairs: Sean Agbor-Enoh, M.D., Ph.D., Esta Sterneck, Ph.D., and Adam Sowalsky, Ph.D.

 

Welcoming remarks

James Gulley, M.D., Ph.D.

Clinical Director, National Cancer Institute, NIH

Richard Childs, M.D.

Scientific Director, National Heart, Lung and Blood Institute, NIH

          

Opening keynote lecture: Cell free DNA as a window into human health and disease

Francis Collins, M.D. Ph.D. 

NIH Distinguished Investigator

National Human Genome Research Institute and former Director of the National Institutes of Health

Introduction by Sean Agbor-Enoh, M.D., Ph.D.

09:15 am - 10:30 am EST
Session 2: Education Session – Foundations in Liquid Biopsies

Session chairs: Bruna Pellini, M.D. and Julia Burnier, Ph.D.

 

Foundations in placental liquid biopsies

Angie Jelin, M.D., Associate Professor of Gynecology and Obstetrics, Johns Hopkins

 

Principles and applications of RNA liquid biopsy               

Iwijn De Vlaminck, Ph.D., Associate Professor of Biomedical Engineering, Cornell University

               

Plasma-derived extracellular vesicle and particle proteins as biomarkers for cancer diagnostics and prognostics

David Lyden, M.D., Ph.D., Professor of Pediatrics, Weill Cornell Medical College

 

Tapping into the genome: Foundations of CSF circulating tumor DNA liquid biopsy in CNS tumors

Alexandra Miller, M.D., Ph.D., Associate Professor of Neurology, NYU Langone

               

Foundations in ctDNA testing after curative-intent treatment in NSCLC

Bruna Pellini, M.D., Assistant Member of Thoracic Oncology, Moffitt Cancer Center

 

10:30 am - 11:00 am EST
Break
11:00 am - 01:00 pm EST
Session 3: Liquid Biopsies of Cells and Extracellular Vesicles in Circulation

Session chairs: Ignatia Barbara Van den Veyver, M.D., and Esta Sterneck, Ph.D.

 

Extracellular vesicles and CTCs in lung cancer, clinical application

Christian Rolfo, M.D., Professor of Hematology and Oncology, Icahn School of Medicine at Mount Sinai

 

Intact fetal cell-based and cell-free DNA-based approaches for non-invasive prenatal screening and testing

Ignatia Barbara Van den Veyver, M.D., Professor of Obstetrics and Gynecology and Molecular and Human Genetics, Baylor College of Medicine

               

The utility of Liquid Biopsy in Immuno-Oncology: an emphasis on circulating tumor cells

Catherine Alix-Panabières, Ph.D., Professor of Medicine, University Medical Centre of Montpellier

 

1-2 additional speakers will be selected from meritorious abstracts

01:00 pm - 03:00 pm EST
Lunch and Poster Session

Poster session

1:00–3:00 pm

 

Lunch career roundtable discussions (advance sign-up required)

Discussion hosts: Addy Alt-Holland, Ph.D., Angie Jelin, M.D., Bruna Pellini, M.D., and Alexander Wyatt, Ph.D.

1:15–2:00 pm 

Career paths TBD

 

03:00 pm - 05:15 pm EST
Session 4: Development of Liquid Biopsy Technologies

Session chairs: Alexandra Miller, M.D., Ph.D. and Aaron Newman, Ph.D.

 

TEMPO: Integrating liquid biopsy proteomics with gene expression data 

Vinit B. Mahajan M.D., Ph.D., Professor of Ophthalmology, Stanford University

 

Leveraging AI in Nanotechnology for Precision Liquid Biopsies and Diagnosis

Tony Y. Hu, Ph.D., F-NAI, F-AIMBE, Distinguished Professor of Biochemistry and Molecular Biology, Biomedical Engineering, and Microbiology, Tulane University

 

Solid and liquid determinants of cancer immunotherapy response

Aaron Newman, Ph.D., Assistant Professor of Biomedical Data Science, Stanford University

 

Improving cancer liquid biopsies through fragmentomics and population studies

Dennis Lo, Ph.D., Professor of Chemical Pathology, The Chinese University of Hong Kong

 

1-2 additional speakers will be selected from meritorious abstracts

Tuesday, May 14, 2024

08:00 am - 10:30 am EST
Session 5: Clinical Implementation of Cell Free DNA Technologies

Session chairs: Aadel Chaudhuri M.D., Ph.D. and Trevor Pugh, Ph.D., FACMG

 

International R&D for ctDNA guided therapies for solid tumors: a clinical investigator's perspective

Bob Li, M.D., Associate Professor of Medicine, Weill Cornell Medical College

 

Multi-analyte and multi-modal cell-free DNA analysis to detect cancer early

Aadel Chaudhuri, M.D., Ph.D., Assistant Professor of Radiation Oncology, Washington University School of Medicine in St. Louis

 

Hereditary cancer surveillance using multi-modal cell-free DNA sequencing

Trevor Pugh, Ph.D., FACMG, Senior Investigator, Ontario Institute for Cancer Research

 

Applying genomics to address health disparities in organ transplants

Hannah Valantine, M.D., Professor of Medicine, Stanford University

 

The NIH IDENTIFY study: Do unusual prenatal cfDNA sequencing results act as a liquid biopsy to detect maternal malignancies?

Diana Bianchi, M.D., Director, Eunice Kennedy Shriver National Institute of Child Health and Human Development, NIH

 

1-2 additional speakers will be selected from meritorious abstracts

10:30 am - 11:00 am EST
Break
11:00 am - 12:30 pm EST
Session 6: Liquid Biopsies: Beyond Genomics

Session chairs: Adam Sowalsky, Ph.D.

 

Salivary and epidermal metabolic profiles associated with Sjögrenʼs disease

Addy Alt-Holland, Ph.D., Associate Professor in Endodontics, Tufts University School of Dental Medicine

               

Epigenomic features in ctDNA from metastatic prostate cancer

Alexander Wyatt, Ph.D., Associate Professor in Urologic Sciences, University of British Columbia

 

2-3 additional speakers will be selected from meritorious abstracts

12:30 pm - 02:00 pm EST
Lunch and Poster Session

Poster session

12:30–2:00 pm

 

Lunch topical issues roundtable discussions (advance sign-up required)

Discussion hosts: Bob Li, M.D., and others

12:45–1:30 pm 

Bob Li: International multi-stakeholder collaboration on liquid biopsy
Others: TBD

02:00 pm - 03:00 pm EST
Session 7: Late Breaking Topics in Liquid Biopsy Research

Session chairs: TBD

 

4-5 topics will be selected from meritorious abstracts 

03:00 pm - 04:00 pm EST
Session 8: Panel Discussion: The Future of Liquid Biopsies

Session moderators: Dennis Lo, Ph.D. and Sean Agbor-Enoh, M.D., Ph.D.

 

Participants: Alexander Wyatt, Ph.D., Diana Bianchi, M.D., Ignatia Barbara Van den Veyver, M.D. and Philip Castle, Ph.D., M.P.H.

 

Audience Q&A at the end of the session