Abstracts and Posters
Abstracts received by the organizing committee were peer-reviewed and scored. The highest-ranking abstracts from eligible trainees were considered for travel awards, as denoted by bold. All abstracts were accepted for poster presentation. A subset of abstracts, noted by *asterisk will also be presented as short talks during the plenary session. A complete book of abstracts will be available for download shortly before the start of the conference.
Poster presenters should prepare their posters to be no larger than 72 inches (6 feet) wide and 48 inches (4 feet) tall. Poster boards will be numbered by abstract sequentially in the upper level atrium. We ask that poster presenters hang their posters on Monday morning and leave them on the poster boards until Tuesday afternoon through both poster sessions.
| Abstract # | Name | Title |
| 001 | Olawumi Giwa | Gene-gene fusions as biomarkers for personalized therapy in glioblastoma multiforme by means of liquid biopsy |
| 003 | Simon Heeke | The emerging role of ctRNA in liquid biopsy – insights from two clinical trials in oncogene-driven non-small cell lung cancer |
| 004* | Irene Casanova-Salas | Circulating tumor extracellular vesicles to monitor metastatic prostate cancer genomics and transcriptomic evolution |
| 005* | Jacob Berchuck | Detecting small cell transformation in patients with EGFR mutant lung adenocarcinoma through epigenomic cfDNA profiling |
| 006 | Sidharth Jain | Monitoring treatment response and toxicity in immune-checkpoint-inhibitor treated metastatic melanoma from cell-free methylated DNA |
| 007 | Derek Wong | Fragmentomic analysis of cell-free DNA reveals cancer associated signatures in TP53 mutation carriers |
| 008* | Francesco Franco | Cystatin SN as an innovative salivary biomarker for periodontitis: a controlled pilot study |
| 009 | Auriel Sanders | Cell-free DNA to unveil potential mechanisms of racial disparities in lung transplant |
| 011 | Liya Xu | Aqueous humor liquid biopsy: a five-year progress in establishing clinical utility for retinoblastoma diagnosis, prognosis, and therapeutic outcomes |
| 013* | Temesgen Andargie | Combined donor- and recipient- cell-free DNA signatures provide accurate detection of cardiac allograft rejection |
| 014 | Fabrice Lucien-Matteoni | Tumor-derived extracellular vesicles as a liquid biomarker of tumor burden in prostate cancer |
| 015 | Fabrice Lucien-Matteoni | Standardized reporting of pre-analytical variables to enhance rigor and reproducibility in liquid biopsy research: experience from the ISEV blood task force |
| 016 | Hyeyeun Lim | Comparative DNA methylation profiling of cirrhosis with and without hepatocellular carcinoma |
| 017* | Liya Xu | Everything everywhere all at once: evolving ocular liquid biopsies |
| 018 | Asia Jordan | Meta-analysis of publicly available datasets for the identification of liquid biomarkers for high-grade serous ovarian cancer |
| 019* | Sarah Woodfield | An indocyanine green-based liquid biopsy test for circulating tumor cells for pediatric liver cancer |
| 020 | Brian Silver | Isolation and characterization of cell-free DNA from cerebral organoids |
| 021 | Hyesik Kong | Cell-free DNA exposes tissue injury profiles leading to primary graft dysfunction before symptoms develop |
| 022* | Venkata Yellapantula | Genome-wide cfDNA fragmentation patterns in cerebrospinal fluid informs medulloblastoma subtypes |
| 023 | Theresa L. Whiteside | Small extracellular vesicles as biomarkers of response in recurrent/metastatic HNSCC patients treated with immunotherapy |
| 024 | Muhtadi Alnababteh | Early post-transplant genomic storm predict allograft function and survival in lung transplant recipients introduction |
| 025 | Jinyun Juan | Sonobiopsy enriches circulating tumor-specific biomarkers in a mouse model of diffuse intrinsic pontine glioma |
| 027 | David Wong | Ultra-short ctDNA: a new paradigm of ctDNA liquid biopsy |
| 028 | Kathleen Ran | Quantification of spinal cord-derived cell free DNA in plasma of patients with metastatic epidural spinal cord compression |
| 029 | Emily Zhao | Cell-free DNA screening results by stage of maternal malignancy |
| 030* | Megan McNamara | Circulating, cell-free methylated DNA reveals cellular sources of graft injury after liver transplant |
| 031 | Asli Munzur | Plasma cell-free DNA histone methylation enables phenotypic and clinical segmentation of metastatic prostate cancer |
| 032 | Harini Lakshminarayanan | Exploring extracellular vesicles as liquid biopsy biomarkers for clear cell renal cell carcinoma |
| 033 | Jeffrey Szymanski | Early detection of malignant and pre-malignant peripheral nerve tumors using cell-free DNA fragmentomics |
| 034 | David Greaves | Cellkeep slide enhances retention of CTCs harvested from patient blood samples using the Parsortix® system. |
| 035 | Hallie Gaitsch | Characterization of plasma and CSF cell-free DNA profiles in patients with multiple sclerosis and progressive multifocal leukoencephalopathy using cell-of-origin methylation analysis |
| 036 | Whitney Do | Antigen reactivity profiles predict prognosis after immunotherapy treatment in hepatocellular carcinoma and cholangiocarcinoma |
| 037 | Mimi Richert | Cell-free DNA to predict severe exacerbations in chronic obstructive pulmonary disease |
| 038 | Kaitlynn Slattery | Measuring cytokine levels in extracellular vesicles isolated from serum and plasma in healthy blood donors: a pilot study |
| 039 | McKenzie Kauss | Comparison between levels of vascular injury markers in extracellular vesicles derived from serum and plasma in healthy volunteers: a pilot study |
| 040 | Zhongping Xu | Small extracellular vesicles in proximal postoperative biofluids of HPV+ oropharyngeal cancer drive M1 macrophage polarization via cGAS-STING pathway activation |
| 041 | Tzu-Chun Chen | Circulating differential methylation allele fraction (DMAF): an alternative to detection of tumor-derived circulating cell-free DNA |
| 042 | Sara Bang-Christensen | Combining mehtylation markers for efficient, blood-based multi cancer detection |
| 044 | Aneesa Bhakta | Glycome profiling with a DNA-barcoded antibody library |
| 045 | Jazmyn Bess | Impact of delayed processing on cfDNA quantity and quality using streck cfDNA tubes: liquid biopsy connect pilot study |
| 046 | Sarven Sabunciyan | Brain specific mRNAs in blood extracellular vesicles are potential biomarkers for detecting transcriptional changes in the brain |
| 047 | Chennan Li | Tracing the clonal dynamic of metastatic castration-resistant prostate cancer over immunotherapy using circulating tumor DNA |
| 048 | Diha Freije | Development of an epigenetic panel for urological cancers |
| 049 | Sukhbir Kaur | Novel CD47 interacting cargo proteins of extracellular vesicles from t lymphoblast and prostate carcinoma cells identified using single vesicle imaging and mass spectrometry |
| 050 | Nafiseh Jafari | Enhanced cell-free DNA extraction from large whole urine volumes: implications for prostate cancer detection |
| 051 | Seka Lazare | Detection of minimal residual disease in lymph predicts recurrence in HPV-negative head and neck cancer patients |
| 052 | Hongzhang He | Dentifying actionable genomic alterations in non-small cell lung cancer through the analysis of extracellular vesicles in plasma |
| 053 | Russell Sundby | Dissecting the circulating proteome in NF1-associated peripheral nerve sheath tumors |
| 054* | Yulin Jin | Cell-free DNA methylation signatures: bridging the gap in ALS biomarker discovery |
| 055 | Chandan Bhambhani | Ultra-short trans-renal circulating tumor DNA in urine for non-invasive liquid biopsy of HPV+ oropharyngeal cancer |
| 056 | Nikki Higa | High purity ctDNA as a model system: evaluating ichorCNA perfomance in silico for improved liquid biopsy accuracy, coverage effects, and size selection efficiency |
| 057 | Sabina Pathan | Multiple methylated markers of malignancy: a non-invasive, multi-cancer diagnostic |
| 058 | Marlene Tartaro | Droplet digital PCR sequencing of cell-free DNA from cerebrospinal fluid for detection of hotspot mutations in glioma |
| 059 | Alessandra Vittorini Orgeas | A pipeline for the identification of disease-specific genetic biomarkers using ngs sequencing data of cfDNAs in human plasma |
| 060 | Hoyoung Maeng | The path to translate genomic findings into a pilot clinical trial of a cell free DNA platform for early detection and monitoring of MMR deficient cancers |
| 061* | Diego de Miguel Perez | COVID-19 proteins in extracellular vesicles are linked to immune, coagulation, and cardiovascular complications and poor outcomes in severe disease patients |
| 062 | Diego de Miguel Perez | Plasma extracellular vesicles and radiomics predict response to immune-checkpoint inhibitors in patients with non-small cell lung cancer |
| 063 | Diego de Miguel Perez | Baseline low extracellular vesicle miRNA-30c and presence of autophagic CTCs predict chemoradiotherapy resistance and poor outcomes in patients with locally advanced non-small cell lung cancer |
| 064 | Balamurugan Kuppusamy | Development of imaging mass cytometry as a tool to characterize circulating tumor cells in pre-clinical mouse models |
| 066 | Tijana Jovanovic-Talisman | Multiparametric characterization of single extracellular vesicles from plasma |
| 067 | Mohamed Adil | Advance prostate cancer detection through epigenomic profiling of cfDNA |
| 068* | Pradeep Chuahan | Enrichment of tumor-associated fragmentomic features detected in cell-free DNA with sonobiopsy in glioma patients |
| 069 | Pradeep Chuahan | Molecular residual disease (MRD) detection by circulating tumor DNA in patients with urothelial and renal cell cancers |
| 070 | Pradeep Chuahan | Urine cell-free DNA fragmentomics to detect genitourinary malignancies and predict pathological response in bladder cancer |
| 071 | Abhirami Thaivalappil | Cell-free DNA as a novel biomarker for disease progression and response to treatment in Hutchinson-Gilford progeria syndrome |
| 072 | Neeti Swarup | Broad range cell-free DNA assessment of lung cancer in indeterminate pulmonary nodules |
| 073 | Han Sang Kim | Unveiling diagnostic biomarkers for colon adenocarcinoma: a proteomic study of human extracellular vesicles and particles |
| 074 | Stephanie Chidester | Performance of nucleic acid-stabilizing blood collection tubes for EV-based liquid biopsies and EV repertoire analyses |
075 | Mohan Uttawar | CellBiopsy based comprehensive molecular profiling of CTC in HER2 tested breast cancer patients reveals novel mediators of early disease progression and therapeutic resistance |