Thursday, March 21, 2024

08:00 am - 08:30 am EST
Registration, Breakfast and Poster Placement
08:30 am - 09:15 am EST
Introduction and Opening Remarks

Len Freedman, Chief Scientific Officer, FNLCR

Dwight Nissley, Director, Cancer Research Technology Program, FNLCR

Dominic Esposito, Director, Protein Expression Laboratory, FNLCR

Session 1: Protein and Antibody Workflows


09:15 am - 09:45 am EST

Avinash Gill, Sr. Principal Scientific Manager, Biomolecular Resources, Genentech

“Efficient high-throughput workflows meet the protein needs of drug discovery campaigns”

09:45 am - 10:15 am EST

Phil Bourne, Director, COBRE Protein Production Core, University of Oklahoma

“Managing a smaller facility: the OU COBRE protein production and characterization core”

10:15 am - 10:30 am EST
10:30 am - 11:00 am EST

Matt McKenna, Senior Field Applications Scientist, Thermo Fisher Scientific

“Optimizing transient protein production”

11:00 am - 11:30 am EST

Ruth Saxl, Senior Manager, MAPP, The Jackson Laboratory

“Developing an antibody validation pipeline”

11:30 am - 12:00 pm EST

Simona Colantonio, Director, CPTAC Antibody Characterization Laboratory, FNLCR

“Antibody characterization at the Frederick National Lab: challenges and opportunities”

12:00 pm - 01:30 pm EST
Lunch with Poster viewing in the Atrium
Session 2: Case Studies



01:30 pm - 02:00 pm EST

Oleg Brodsky, Senior Principal Scientist, Pfizer 

“Production of human KAT6A acetyltransferase quaternary complex in insect cells”

02:00 pm - 02:30 pm EST

Kinlin Lee Chao, IBBR, University of Maryland

“Production of 2H/13C/15N labeled NIST-Fab fragment in Komagataella phaffii for NMR studies"

02:30 pm - 03:00 pm EST

Robert D’Ippolito, Scientist II, RAS Mass Spectrometry, FNLCR

“Using mass spectrometry to characterize neurofibromin”

03:00 pm - 03:30 pm EST
Coffee break with poster viewing in the Atrium
Roundtable discussions
03:30 pm - 04:15 pm EST breakout rooms
Individual roundtable discussions
04:15 pm - 05:00 pm EST Auditorium
Readout and group discussion
05:00 pm EST 8411 Broadband Drive, Unit K, Frederick, MD
Happy Hour at Rockwell Brewery
Dinner on your own

Enjoy downtown Frederick eating establishments!

Friday, March 22, 2024

08:00 am - 08:30 am EST
Session 3: Structural Biology
08:30 am - 09:15 am EST
Keynote Presentation

Angela Gronenborn, Rosalind Franklin Professor and Chair,
Department of Structural Biology, University of Pittsburgh School of Medicine

“The awesome power of fluorine NMR—from drugs to cells”

09:15 am - 09:45 am EST

Rachel Harding, Principal Investigator, Structural Genomics Consortium

“Target 2035: the quest to develop a pharmacological modulator for every human protein”

09:45 am - 10:15 am EST

Jana Ognjenovic, Group Leader, Advanced Cryo-EM Technology Group, FNLCR

“Cold hard truths: navigating sample prep challenges in CryoEM”

10:15 am - 10:45 am EST
Break with Poster viewing in the Atrium
11:00 am - 12:40 pm EST
Session 4: Technology Department
10:45 am - 11:15 am EST

Bill Gillette, Principal Scientist, Protein Expression Laboratory, FNLCR

“Vibrio natriegens the need for speed and more”

11:15 am - 11:45 am EST

Carter Mitchell, Chief Scientific Officer, Kemp Proteins

“ProtFAUNA: fast annotation of uncharacterized nucleic acids to gain insights into the hypothetical
global proteome”

11:45 am - 12:15 pm EST

James Kostas, Senior Scientist, Merck

“Validation of LabChip GXII for structural enablement construct triage”

12:15 pm - 12:45 pm EST

Austin Graves, Senior Field Applications Specialist, Refeyn Inc.

“Understanding biomolecular behavior with mass photometry”

12:45 pm EST
Closing Remarks