Agenda

Thursday, May 14, 2020

10:00 am - 10:10 am EST
INTRODUCTION

Nirali N. Shah, Pediatric Oncology Branch, NCI

10:10 am - 11:00 am EST
NEUROTOXICITY (Session Chairs: Juliane Gust and Haneen Shalabi)

Current State of the Art in CAR T-cell Neurotoxicity 
Speaker: Haneen Shalabi, Pediatric Oncology Branch, NCI

Neuroimaging in CAR T-cell Therapy 
Speaker: Agne Taraseviciute, Pediatric Hematology/Oncology, CHLA

Neurocognitive Evaluations
Speaker: Pam Wolters, Pediatric Oncology Branch, NCI

Establishing Comprehensive and Uniform Biologic Correlatives
Speaker: Juliane Gust, Pediatric Neurology, Seattle Children’s

11:00 am - 11:50 am EST
PSYCHOSOCIAL (Session Chair: Allison Leahy)

The Patient/Parent Experience with CAR T-cells
Speaker: Carlos Sandi, Patient/Parent Advocate

Patient Reported Quality of Life after Tisagenlecleucel
Speaker: Ted Laetsch, Pediatrics Hematology/Oncology, UT Southwestern

PROs: What should be used for CAR T-cells
Speaker: Allison Leahy, Pediatric Hematology/Oncology, CHOP

Comprehensive Care Model
Speaker: Lori Wiener, Pediatric Oncology Branch, NCI

12:00 pm - 01:00 pm EST
LUNCH
01:00 pm - 01:40 pm EST
INFECTIONS AND IMMUNE RECONSTITUTION (Session Chair: Rebecca Gardner)

Infections and CAR T-cells
Speaker: Veronique Nussenblatt, Infectious Disease, NIAID, NIH

Immune Reconstitution and Vaccine Strategies Post CAR
Speaker: Josh Hill, Allergy and Infectious Diseases, Fred Hutch Cancer Research Center

 

01:40 pm - 02:20 pm EST
OTHER END-ORGAN TOXICITIES (Session Chair: Nirali Shah)

Optimizing Treatment of Extramedullary Disease
Speaker: Kevin Curran, Pediatric Hematology/Oncology, MSKCC

Hematologic Toxicities
Speaker: Tim Olson, Pediatric BMT, CHOP

Hemophagocytic Lymphohistiocytosis
Speaker: Nirali N. Shah, Pediatric Oncology Branch, NCI

02:20 pm - 02:30 pm EST
BREAK
02:30 pm - 03:30 pm EST
RELAPSE AND SUBSEQUENT NEOPLASMS (Session Chairs: Michael Pulsipher and Colleen Annesley)

How to Evaluate a New Malignancy Post CAR
Speakers: Hao-Wei Wang, Hematopathology, NCI & Javed Khan, Genetics Branch, NCI

Prevention of Early Failure of CAR T-cells 
Speaker: Steve Grupp, Pediatric Hematology/Oncology, CHOP

Management of CAR T-cell Relapse
Speaker: Colleen Annesley, Pediatric Hematology/Oncology, Seattle Children’s

Role for Consolidative HSCT
Speaker: Mike Pulsipher, Pediatric Hematology/Oncology, CHLA

03:30 pm - 04:15 pm EST
OTHER COLLABORATIONS/INSIGHTS/ADVICE

Transplant Late Effects Study
Speaker: Christine Duncan, Pediatric BMT, Children’s Hospital Boston

Collaborating with CIBMTR
Speaker: Marcelo Pasquini, CIBMTR

Real-World Kymriah
Speaker: Liora Schultz, Pediatric Hematology/Oncology, Stanford

04:15 pm - 04:30 pm EST
CONCLUSION

Action Items and Future Directions
Speaker: Nirali N. Shah, Pediatric Oncology Branch, NCI