Agenda

10:00 am - 10:10 am EST

Eric Freed, Ph.D. (HIV Dynamics and Replication Program, National Cancer Institute)

Welcoming remarks

10:10 am - 10:50 am EST

H. Clifford Lane, M.D. (Clinical Director, National Institute of Allergy and Infectious Diseases)

Conducting clinical research in the setting of an Ebola outbreak

10:50 am - 11:30 am EST

Silvia Bertagnolio, M.D. (World Health Organization)

Global status of HIV drug resistance and policy implications for low- and middle-income countries

11:30 am - 12:10 pm EST

Eric Freed, Ph.D.

Envelope-mediated mechanisms of HIV drug resistance

12:10 pm - 01:10 pm EST

Lunch

01:10 pm - 01:50 pm EST

Shyam Kottilil, M.D., Ph.D. (Institute of Human Virology and University of Maryland School of Medicine)

Resistance to direct acting antiviral therapy for HCV and HBV

01:50 pm - 02:30 pm EST

Robert Bonomo, M.D. (Case Western Reserve University)

The renaissance of beta-lactamase inhibitors

02:30 pm - 03:10 pm EST

Lawrence Fong, M.D. (University of California, San Francisco, School of Medicine)

Immune intrinsic mechanism of resistance to checkpoint inhibition

03:10 pm - 03:40 pm EST

Break

03:40 pm - 04:20 pm EST

Jeanne Marrazzo, M.D. (University of Alabama at Birmingham School of Medicine)

Antimicrobial resistance in bacterial sexually transmitted infections

04:20 pm - 05:00 pm EST

David Sullivan, M.D. (Johns Hopkins Bloomberg School of Public Health)

Malaria resistance: Pharmacokinetics and pharmacodynamics of resistant Plasmodium — The glass is half-full

05:00 pm - 05:40 pm EST

Bree Aldridge, Ph.D. (Tufts University School of Medicine and School of Engineering)

Engineering optimized combination therapies for TB

05:40 pm - 05:45 pm EST

Stephen Hughes, Ph.D. (HIV Dynamics and Replication Program, National Cancer Institute)

Closing remarks

Therapeutic Interventions and Resistance Mechanisms