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  1. 1.   Specific Binding and Chemotactic Activity of mBD4 and Its Functional Orthologue hBD2 to CCR6-expressing Cells
  2. Rohrl, J.; Yang, D.; Oppenheim, J. J.; Hehlgans, T.
  3. Journal of Biological Chemistry. 2010, Mar; 285(10): 7028-7034.
  1. 2.   Expression of mouse beta-defensin-3 in MDCK cells and its anti-influenza-virus activity
  2. Jiang, Y.; Wang, Y. L.; Kuang, Y.; Wang, B. N.; Li, W. Y.; Gong, T. X.; Jiang, Z. H.; Yang, D.; Li, M. Y.
  3. Archives of Virology. 2009 154(4): 639-647.
  1. 3.   Defensin-related peptide 1 (Defr1) is allelic to Defb8 and chemoattracts immature DC and CD4(+) T cells independently of CCR6
  2. Taylor, K.; Rolfe, M.; Reynolds, N.; Kilanowski, F.; Pathania, U.; Clarke, D.; Yang, D.; Oppenheim, J.; Samuel, K.; Howie, S.; Barran, P.; MacMillan, D.; Campopian, D.; Dorin, J.
  3. European Journal of Immunology. 2009 39(5): 1353-1360.
  1. 4.   The conserved salt bridge in human alpha-defensin 5 is required for its precursor processing and proteolytic stability
  2. Rajabi, M.; de Leeuw, E.; Pazgier, M.; Li, J.; Lubkowski, J.; Lu, W.
  3. Journal of Biological Chemistry. 2008 283(31): 21509-21518.
  1. 5.   Identification and biological characterization of mouse beta-defensin 14, the orthologue of human beta-defensin 3
  2. Roehrl, J.; Yang, D.; Oppenheim, J. J.; Hehlgans, T.
  3. Journal of Biological Chemistry. 2008 283(9): 5414-5419.
  1. 6.   Analysis and separation of residues important for the chemoattractant and antimicrobial activities of beta-defensin 3
  2. Taylor, K.; Clarke, D. J.; McCullough, B.; Chin, W.; Seo, E.; Yang, D.; Oppenheim, J.; Uhrin, D.; Govan, J.; Campopiano, D. J.; MacMillan, D.; Barran, P.; Dorin, J. R.
  3. Journal of Biological Chemistry. 2008 283(11): 6631-6639.
  1. 7.   Toward understanding the cationicity of defensins - Arg and Lys versus their noncoded analogs
  2. Zou, G. Z.; de Leeuw, E.; Li, C.; Pazgier, M.; Li, C. Q.; Zeng, P. Y.; Lu, W. Y.; Lubkowski, J.; Lu, W. Y.
  3. Journal of Biological Chemistry. 2007, Jul; 282(27): 19653-19665.
  1. 8.   Impact of pro segments on the folding and function of human neutrophil alpha-defensins
  2. Wu, Z. B.; Li, X. Q.; Ericksen, B.; de Leeuw, E.; Zou, G. Z.; Zeng, P. Y.; Xie, C.; Li, C.; Lubkowski, J.; Lu, W. Y.; Lu, W. Y.
  3. Journal of Molecular Biology. 2007, Apr; 368(2): 537-549.
  1. 9.   Studies of the biological properties of human beta-defensin 1
  2. Pazgier, M.; Prahl, A.; Hoover, D. M.; Lubkowski, J.
  3. Journal of Biological Chemistry. 2007, Jan; 282(3): 1819-1829.
  1. 10.   Human defensins: synthesis and structural properties
  2. Pazgier, M.; Li, X.; Lu, W.; Lubkowski, J.
  3. Current Pharmaceutical Design. 2007 13(30): 3096-3118.
  1. 11.   Defensin participation in innate and adaptive immunity
  2. Yang, D.; Liu, Z. H.; Tewary, P.; Chen, Q.; De la Rosa, G.; Oppenheim, J. J.
  3. Current Pharmaceutical Design. 2007 13(30): 3131-3139.
  1. 12.   Crystal structures of human alpha-defensins HNP4, HD5, and HD6
  2. Szyk, A.; Wu, Z. B.; Tucker, K.; Yang, D.; Lu, W. Y.; Lubkowski, J.
  3. Protein Science. 2006, Dec; 15(12): 2749-2760.
  1. 13.   Expression and purification of recombinant human alpha-defensins in Escherichia coli
  2. Pazgier, M.; Lubkowski, J.
  3. Protein Expression and Purification. 2006, Sep; 49(1): 1-8.
  1. 14.   theta-defensins prevent HIV-1 Env-mediated fusion by binding gp41 and blocking 6-helix bundle formation
  2. Gallo, S. A.; Wang, W.; Rawat, S. S.; Jung, G.; Waring, A. J.; Cole, A. M.; Lu, H.; Yan, X. X.; Daly, N. L.; Craik, D. J.; Jiang, S. B.; Lehrer, R. I.; Blumenthal, R.
  3. Journal of Biological Chemistry. 2006, Jul; 281(27): 18787-18792.
  1. 15.   Human beta-defensins
  2. Pazgier, M.; Hoover, D. M.; Yang, D.; Lu, W.; Lubkowski, J.
  3. Cellular and Molecular Life Sciences. 2006, Jun; 63(11): 1294-1313.
  1. 16.   Human alpha-defensins block papillomavirus infection
  2. Buck, C. B.; Day, P. M.; Thompson, C. D.; Lubkowski, J.; Lu, W. Y.; Lowy, D. R.; Schiller, J. T.
  3. Proceedings of the National Academy of Sciences of the United States of America. 2006, JAN 31; 103(5): 1516-1521.
  1. 17.   Inhibition of pathologic retinal neovascularization by alpha-defensins
  2. Economopoulou, M.; Bdeir, K.; Cines, D. B.; Fogt, F.; Bdeir, Y.; Lubkowski, J.; Lu, W. Y.; Preissner, K. T.; Hammes, H. P.; Chavakis, T.
  3. Blood. 2005, DEC 1; 106(12): 3831-3838.
  1. 18.   Inhibition of pathological retinal neovascularization by alpha-defensins
  2. Chavakis, T.; Bdeir, K.; Cines, D. B.; Fogt, F.; Bdeir, Y.; Lubkowski, J.; Preissner, K. T.; Hammes, H. P.; Economopoulou, M.
  3. Blood. 2005, NOV 16; 106(11, Part 1): 1024A, Abstract 3678-1024A, Abstract 3678.
  1. 19.   Human beta-defensins suppress human immunodeficiency virus infection: Potential role in mucosal protection
  2. Sun, L. L.; Finnegan, C. M.; Kish-Catalone, T.; Blumenthal, R.; Garzino-Demo, P.; Maggiore, G. M. L.; Berrone, S.; Kleinman, C.; Wu, Z. B.; Abdelwahab, S.; Lu, W. Y.; Garzino-Demo, A.
  3. Journal of Virology. 2005, NOV; 79(22): 14318-14329.
  1. 20.   Reconstruction of the conserved beta-bulge in mammalian defensins using D-amino acids
  2. Xie, C.; Prahl, A.; Ericksen, B.; Wu, Z. B.; Zeng, P. Y.; Li, X. Q.; Lu, W. Y.; Lubkowski, J.; Lu, W. Y.
  3. Journal of Biological Chemistry. 2005, SEP 23; 280(38): 32921-32929.
  1. 21.   Mouse cathelin-related antimicrobial peptide chemoattracts leukocytes using formyl peptide receptor-like 1/mouse formyl peptide receptor-like 2 as the receptor and acts as immune adjuvant
  2. Kurosaka, K.; Chen, Q.; Yarovinsky, F.; Oppenheim, J. J.; Yang, D.
  3. Journal of Immunology. 2005, MAY 15; 174(10): 6257-6265.
  1. 22.   Human neutrophil alpha-defensin 4 inhibits HIV-1 infection in vitro
  2. Wu, Z. B.; Cocchi, F.; Gentles, D.; Ericksen, B.; Lubkowski, J.; DeVico, A.; Lehrer, R. I.; Lu, W. Y.
  3. Febs Letters. 2005, JAN 3; 579(1): 162-166.
  1. 23.   Multiple roles of antimicrobial defensins, cathelicidins, and eosinophil-derived neurotoxin in host defense
  2. Yang, D.; Biragyn, A.; Hoover, D. M.; Lubkowski, J.; Oppenheim, J. J.
  3. Annual Review of Immunology. 2004 22: 181-215.
  1. 24.   Many chemokines and defensins exhibit antimicrobial and immunoadjuvant activities
  2. Oppenheim, J.; Yang, D.; Biragyn, A.; Kwak, L.
  3. Annals of the Rheumatic Diseases. 2003, JUL; 62(Suppl. 1): 32-32.
  1. 25.   Roles of antimicrobial peptides such as defensins in innate and adaptive immunity
  2. Oppenheim, J. J.; Biragyn, A.; Kwak, L. W.; Yang, D.
  3. Annals of the Rheumatic Diseases. 2003 62(Suppl. 2): 17-21.
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