(NIH/NCI-F) - Access restricted to NIH & NCI-F sites | (NCI-F) - Access restricted to National Cancer Institute at Frederick

Cancer Research  ||  Chemistry  ||  Sharing Tools & Resources (STAR)



 | A | B | C | D | E | F | G | H | I | J | K | L | M | N | O | P | Q | R | S | T | U | V | W | X | Y | Z |


  • Allen Brain Atlases - Free Atlases in the data portal include the Mouse Brain, Developing Mouse Brain, Mouse Connectivity, Mouse Spinal Cord, Non-Human Primate, Human Brain, Developing Human Brain, Gioblastoma, and more. The portal is a growing collection of online public resources integrating extensive gene expression and neuroanatomical data, with a novel suite of search and viewing tools. For new and experienced users of the Allen Brain Atlas resources, view the YouTube channel of Allen Institute for Brain Science webinars and tutorials for introductory overviews as well as guided tours focused on specific tools. Read more about the Allen Institute for Brain Science. (NIH/NCI-F)
  • AntiBase 2017 Update, the Natural Compound Identifier, is available to NCI at Frederick researchers as a networked CD-ROM via the Scientific Library. AntiBase is a comprehensive database of more than 44,000 natural compounds from micro-organisms and higher fungi. and includes descriptive data; physico-chemical data; spectroscopic data; biological data; information on origin and isolation and a summary of literature sources. (NCI-F only)
    • NOTE: AntiBase will only open in ChemBioFinder. To have ChemBioFinder installed on your computer, as part of theChemBioOffice software package, contact DMS Computer Services Help Desk at 301-846-5115.
    • For access to Antibase, please contact Alan Doss at 301-846-6249, or by e-mail at


  • BindingDB - The Binding Database (BindingDB) is a public, web-accessible database of measured binding affinities, focusing chiefly on the interactions of proteins considered to be drug-targets with small, drug-like molecules. BindingDB also offers tools for virtual screening of candidate ligands. Learn more about BindingDB - Article 1Article 2.
  • Biobase Biological Databases - For access to the Human Gene Mutation Database (HGMD). Individual registration and login required. Enter the code 1881-6975-97565225 in the license field during the account registration process. For additional bioinformatics resources, see NIH's Analysis Tools & Databases list(NIH/NCI-F)
  • BioCyc - Contains comprehensive metabolic pathway information for human and more than 17,000 microbial organisms. You may search by pathway name, reaction type, gene name, enzyme and more to find the information you require and to begin exploring individual and related pathways. Note: for unlimited access to BioCyc, you must create a BioCyc account while on campus and login to it while on campus or while logged into the Library's "Off-Site Access." (NCI-F only)  
  • bioDBnet - Biological Data Base network, developed at the Advanced Biomedical Computing Center (ABCC), NCI at Frederick, integrates many public databases such as Ensembl, NCBI-Gene, GO, UniProt, Affy, etc. It has tools to get detailed annotation reports and also to convert between biological identifiers like proteins to genes or pathways to genes or RefSeq proteins to Ensembl proteins, etc. Any questions or requests to bioDBnet can be made through the bioDBnet Contact Form.
  • Bioinformatics Analysis Tools & Databases from NIH Library - See the list of bioinformatics resources licensed by the NIH Library. Access requirements vary so please read information accompanying each resource on list. (NIH/NCI-F)
  • bioRxiv - The preprint server for biology, speeds scientific discovery by allowing access to reports of the latest scientific research before it is officially published in the scientific literature. It allows sharing of discoveries prior to or at the same time as submitting to peer reviewed journals providing more opportunities for feedback and earlier credit for the work. Article.  
  • BIOSIS Citation Index (1926-present) via Web of Science (WOS) - Use the pulldown menu next to Web of Science Core Collection to select the database.(NIH/NCI-F)
  • Britannica Online - Encyclopedia Britannica online - limited free access.



  • Cambridge Structural Database via WebCSD - Online portal to the Cambridge Structural Database. Read PMC article about WebCSD (NIH/NCI-F)
  • CancerMine - identifies cancer Drivers, Oncogenes, and Tumor Suppressors from the biomedical literature and displays the findings in graphical and tabular formats for ease of discovery. Article
  • Carcinogenic Potency Database - From TOXNET, NLM's Toxicology Data Network.
  • CBL Nitric Oxide Database - Learn about Nitric Oxide Research in the Chemical Biology Laboratory, Frederick National Lab, using this searchable Nitric Oxide Diazeniumdiolate (or NONOates) Reagents Database.
  • Chemical Carcinogenesis Research Information Service (CCRIS) - From TOXNET, NLM's Toxicology Data Network, carcinogenicity and mutagenicity test results for over 8,000 chemicals.
  • ChemID Plus - From TOXNET, NLM's Toxicology Data Network, a searchable dictionary of over 370,000 chemicals (names, synonyms, and structures). Includes links to NLM and other databases and resources.
  • Chemistry Resources
  • ChemNavigator - Available to all NIH affiliated scientific researchers, NIH has made an agreement with ChemNavigator to provide a current and comprehensive database of commercially accessible drug discovery screening compounds. If you are an NIH researcher, once you register in the system, you'll have full access to the iResearch System. Then you will be able to perform chemical structure searches for compound samples of interest and purchase these samples through this on-line system. (NCI/NCI-F)
  • CINAHL Plus - Via NIH's EBSCOhost; the Cumulative Index to Nursing and Allied Health Literature (CINAHL Plus) provides indexing for 4,500 journals from the fields of nursing and allied health, with indexing back to 1937. CINAHL Plus also contains searchable cited references for more than 1,340 journals. Full text material includes nearly 80 journals plus legal cases, clinical innovations, critical paths, drug records, research instruments and clinical trials. Click on EBSCOhost Research Databases, then CINAHL Plus. (NIH/NCI-F)
  • - (1982 - ). With over 400,000 trials in 220 countries, this database, a service of the NIH, is a registry of federally and privately supported clinical trials conducted in the United States and around the world. Find trials for a specific medical condition or other criteria in the registry.
  • Cochrane Library - The Cochrane Library is designed to provide information and evidence to support decisions taken in health care and to inform those receiving care. The Cochrane Library consists of a regularly updated collection of evidence-based medicine databases: The Cochrane Database of Systematic Reviews (Cochrane Reviews), The Cochrane Central Register of Controlled Trials (CENTRAL), Cochrane Clinical Answers, Systematic Reviews from Epistemonikos, Health Systems Evidence, Social Systems Evidence, Editorials, and Special Collections.  Many of the reviews analyze the efficacy and adverse effects of pharmacological agents and provide a useful resource for completed or abandoned clinical studies. (NIH/NCI-F)
  • Cold Spring Harbor Protocols - Over 700 methods in molecular and cell biology. Free individual registration is required prior to your first use. Login with your personal username and password for each future use. For more protocols, see also Springer Nature Experiments, Methods in Enzymology and the Current Protocols series titles in OneSearch(NIH/NCI-F)
  • ConceptGen - From NCIBI, a gene set enrichment testing and gene set relation mapping tool that can help you identify, explore, and visualize relationships and significant overlaps among sets of genes (concepts). ConceptGen is built on a repository of conceptual data drawn from diverse areas.
  • Contract-Awarded Labor Category (CALC) Tool - If you are looking for labor rates for specific positions and contractors, this site from the General Services Administration (GSA) allows contracting officers and specialists to conduct research and price analysis for professional labor categories across a database of contract awarded prices for 48,000 labor categories from more than 5,000 recent GSA contracts.  It lists examples from the rate lists it searches with links to those lists providing rates that are “fully burdened”. 
  • Current Contents Connect (1998-present) via Web of Science (WOS) - Use the pulldown menu next to Web of Science Core Collection to select the database. (NIH/NCI-F)
  • Current Index to Statistics Extended Database - From 1975, indexes publications in statistics and related fields. (NIH/NCI-F)
  • Cytoscape (software) - An open source bioinformatics software platform for visualizing molecular interaction networks and integrating these interactions with gene expression profiles and other state data. This free software needs to be downloaded on individual computers. The MetScape Plugin for Cytoscape provides a bioinformatics framework for the visualization and interpretation of metabolomic and expression profiling data in the context of human metabolism.



  • DailyMed - A public service from NLM, provides information about marketed drugs including FDA approved labels (package inserts).
  • Data Citation Index (1900-present) via Web of Science (WOS) - Use the pulldown menu next to Web of Science Core Collection to select the database.(NIH/NCI-F)
  • - Provides free public access to machine readable datasets generated by the Executive Branch of the Federal Government; includes access to searchable data catalogs - the "raw" data catalog, the tool catalog, and the geodata catalog.
  • DAVID - Database for Annotation, Visualization, & Integrated Discovery - The DAVID Bioinformatics Resources database, developed by the Laboratory of Human Retrovirology Immunoinformatics (LHRI), Leidos Biomedical Research, Inc., provides a comprehensive set of functional annotation tools for investigators to understand biological meaning behind large lists of genes. Read an article published in Nature Protocols describing a step-by-step procedure for using DAVID. Contact DAVID Bioinformatic Team - Brad T Sherman, Bioinformatics Manager, (301) 846-7694.
  • Derwent Innovations Index (1963-present) via Web of Science (WOS) - Use the pulldown menu next to Web of Science Core Collection to select the database.(NIH/NCI-F)
  • Dictionary of Natural Products (DNP) Online - A comprehensive database of 170,000 natural products which includes names and synonyms, formulae, chemical structures, CAS Registry Numbers, extensive source data, uses and applications, physical state, melting point, boiling point, pKa, and key literature citations, searchable by text or substructure. A comprehensive type of compound classification scheme brings together compounds that are biogenetically related. DNP is restricted to 1-2 concurrent NCI-F users; please logoff after each session. If needed, a free browser plug-in is available on the left side of the screen, "Get the Plug-in". Please call Alan Doss at x6249 for searching assistance. (NCI-F only)
  • DXplain - Diagnostic Decision Support (DXplain) is a decision support system using clinical findings (signs, symptoms, labs) to produce a ranked list of diagnoses. For each diagnosis, it provides justification for consideration, further clinical data to collect, and atypical findings. DXplain doesn't offer definitive medical consultation and should not be used as a substitute for physician diagnostic decision making. Access requires entering your NIH email address. (NIH/NCI-F)
  • DynaMed - A clinical reference tool created by physicians for physicians, residents, nurse practitioners and other health care professionals for use at the point-of-care with clinically-organized summaries for more than 3,400 topics.  Editors monitor journals, journal review services, systematic review collections, guideline collections, drug information sources and other relevant sources. (NIH/NCI-F)
  • DynaMed and Micromedex with Watson - DynaMed and Micromedex with Watson seamlessly combines the clinical expertise and extensive, curated disease content of DynaMed, with the comprehensive view into treatment options with the depth and breadth of drug information and AI search capabilities of IBM Micromedex, to provide users with evidence-based insights for optimal clinical decision making which can lead to improved patient outcomes. (NIH/NCI-F)



  • EBSCOhost eBooks - Subscribed items in Library's collection available by title via OneSearch on the Library's homepage. (NCI-F only)
  • Elsevier Pathway Studio Software - NCI researchers (includes NCI-F) have unlimited access to the latest version of Elsevier's Pathway Studio software with the Mammalian (protein-centric) knowledge base as well as the premium DiseaseFx (disease-centric), and ChemEffect (compound-centric) knowledgebases, as well as the MedScan text mining module. Researchers also have access to the NCI's high-quality HyNet Yeast 2-Hybrid Protein Interaction Database .The knowledge bases include molecular facts retrieved from Elsevier's journals as well as facts retrieved from articles from other leading scientific publishers and from PubMed abstracts. Pathway Studio lets molecular biologists work in an interactive graphical environment to connect findings from independent research projects, analyze experimental data, and to develop new findings and publish. Frederick Support: NCI investigators located in Frederick are asked to utilize the DMS Help Desk for all Pathway Studio issues. Service requests submitted to DMS Help Desk for software registration should be directed to (NCI/NCI-F)
  • EcoSal Plus - Based on the classic print reference, Escherichia coli and Salmonella: Cellular and Molecular Biology, EcoSal Plus online publishes expert reviews covering E. coli, Salmonella, and other members of the family Enterobacteriaceae and their use as model microbes for biological explorations. (NIH/NCI-F)
  • Embase - With over 24 million indexed records and more than 7,600 currently indexed peer-reviewed journals, Embase is a  multipurpose and up-to-date database covering the most important international biomedical literature from 1947 to the present. Embase includes coverage and in-depth indexing of the drug-related and clinical literature, with a particular focus on comprehensive indexing of adverse drug reactions; emphasis on Evidence Based Medicine (EBM) indexing including systematic reviews, and coverage and indexing of journals and articles relevant to the development and use of medical devices. (NCI/NCI-F)
  • Ensembl - Genome database and integrated browser, funded by the European Molecular Biology Laboratory and the Wellcome Trust Sanger Institute allows you to graphically navigate publicly available genomics data to quickly find Genes, SNPs, Regulatory features, and Sequences, and to compare sequences against multiple species. Learn more through WebinarsOnline Tutorials.
  • Essential Science Indicators – This analytical tool allows users to identify top-performing research in Web of Science Core Collection.  Identify and compare highly cited authors, institutions, journals, countries/regions, and research fields, and view top papers affiliated with these entities. (NCI/NCI-F)


  • F1000Research - F1000Research is an Open Science publishing platform offering open access publication of posters, slides and articles with open peer review.  (NIH/NCI-F).
  • Faculty Opinions - (previously F1000Prime) identifies and evaluates the most important articles in biology and medical research publications. Composed of 8,000 Faculty Members — senior scientists and leading experts in all areas of biology and medicine — plus their associates, the Faculty recommends the most important articles, rating them and providing short explanations for their selections.  (NIH/NCI-F)
  • Faculty Reviews - Faculty Reviews includes review articles in biology and medicine written by members of Faculty Opinions with the aim of covering emerging concepts and the most recent advances in their field over the past 1-3 years.  (NIH/NCI-F)
  • FSI (Foreign Service Institute) Language Courses - These free course materials cover over 40 languages from the most spoken in the world to some less well known ones.


  • Gene2MeSH - An automated literature-based genome annotation using MeSH.
  • GeneSpring (Software) - From Agilent Technologies, includes GeneSpring GX for microarray data and Agilent's ArrayCGH Analytics ; combines a highly scalable architecture, a rich set of analysis tools, and a series of programmatic interfaces that enable multi-campus enterprises to maximize the value of their research; offers an expanding suite of applications designed to store multiple data types including gene expression, genotyping, comparative genomic hybridization, and proteomics data. Access Information: Contact the NIH Help Desk at 301-496-4357 (6:00 am - 6:00 pm); Email:; Web: (NIH/NCI-F)
  • Gene Ontology (GO) - A major bioinformatics initiative with the aim of standardizing the representation of gene and gene product attributes across species and databases. The project provides a controlled vocabulary of terms for describing gene product characteristics and gene product annotation data from GO Consortium members.
  • GIDEON: Global Infectious Diseases & Epidemiology Network - GIDEON (Global Infectious Diseases and Epidemiology Online Network) is the world’s premier Global Infectious Disease knowledge management tool.  GIDEON is used for Diagnosis Support and Informatics in the fields of Tropical and Infectious diseases, Epidemiology, Microbiology and Antimicrobial Chemotherapy. (NIH/NCI-F)
  • Grant Forward - Infers and aggregates interests from several sources such as a researcher's CV, or publication history, matching the profile with relevant funding opportunities. Users must first create an account at:, using an email address that ends in "". (NIH/NCI-F)



  • HIV Databases - These databases contain data on HIV genetic sequences, immunological epitopes, drug resistance-associated mutations, and vaccine trials. Also included is access to a large number of tools that can be used to analyze these data. This project is funded by the Division of AIDS of the National Institute of Allergy and Infectious Diseases (NIAID), NIH.
  • HSTalks (Henry Stewart Talks) - Biomedical & Life Sciences Collection: this series of over 3,000 specially prepared animated audiovisual presentations with synchronized narration by world leading scientists is keeping researchers informed. The collection is constantly being expanded with hundreds of leading world experts recording presentations especially for Henry Stewart Talks. (NIH/NCI-F)
  • Human Gene Mutation Database (HGMD) Professional - From Biobase, the professional version of the Human Gene Mutation Database (HGMD) provides up-to-date information on human inherited gene mutations. It allows researchers to assess the novelty of identified gene mutations. The mutations in the database are manually curated from the scientific literature. They are mapped to the genome and can be searched by motif, type of nucleotide or amino acid substitution, and location within a splice site or regulatory region. View help resources, including user manuals and tutorials.

    Access is provided at . Individual registration and login required. Enter the code 1881-6975-97565225 in the license field during the account registration process. For additional bioinformatics resources, see NIH's Analysis Tools & Databases list. (NIH/NCI-F)

  • Human Metabolome Database (HMDB) - A freely available electronic database containing detailed information about small molecule metabolites found in the human body. It is intended to be used for applications in metabolomics, clinical chemistry, biomarker discovery and general education.



  • IEEE Explore Digital Library - Resource for access to scientific and technical content published by the Institute of Electrical & Electronics Engineers (IEEE).  The database includes full-text, searchable content published since 1988, with select content dating back to 1872.  Includes conference proceedings, transactions, standards, and journal articles in biomedical engineering, data analysis, biomedical imaging, medical devices, health informatics, and more. (NIH/NCI-F)
  • InCites (1980-present) via Web of Science (WOS) - This tool analyzes institutional research productivity, monitors collaboration activity for authors and institutions, identifies influential researchers, and reveals areas of research opportunity.  Use the link at the top of the Web of Science page to access the database.  A Web of Science login (free, one-time registration) is required for access for InCites.  (NIH/NCI-F)
  • Ingenuity Pathways Analysis  (IPA) - A web-based bioinformatics tool from Ingenuity Systems allowing researchers to search, analyze, and graphically view molecular interactions, biological functions, and diseases. Access Information: IPA is available to all researchers affiliated with the NCI. Please use the registration link below to initiate your user account (NCI affiliated e-mail address required).REGISTRATION: Enrollment is open to all researchers within the NCI. You must first submit a request through “NCI at Your Service” to be placed on the list of authorized NCI users. Then you can proceed to the link shown below to activate your private user account.  NCI User Account Activation Request Form: (NIH/NCI-F)
  • InterDok-Directory of Published Papers - DoPP (Directory of Published Papers) offers free access to locate research papers, especially those not yet presented or published.



  • Journal/Author Name Estimator (JANE) - A free resource tool for finding the perfect journal in which to publish your research, from The Biosemantics Group. Copy and paste your manuscript's abstract or type in the key concepts of your paper. You will get a list of journals, sorted by confidence score, once you click the Find Journals button. Learn more about JANE.
  • Journal Citation Reports (JCR) - consists of Journal Science Reports and Journal Social Science Reports and is a unique resource that allows you to evaluate and compare journals using citation data drawn from over 11,000 scholarly and technical journals from more than 3,300 publishers in over 80 countries. Data includes most frequently cited journals in a field; Highest impact journals in a field. (NIH/NCI-F)
  • JoVE Science Education Database - Learn or train others in laboratory fundamentals using easy-to-understand video demonstrations in 15 subject collections, each with 15 core videos, and links to a variety of application videos. Topics include JoVE Core, Behavioral Science, Biology I and II, Cell Biology, Developmental Biology, General Laboratory Techniques, Lab Animal Research, Neuroscience, Analytical Chemistry, Biochemistry, Genetics, Basic Methods in Cellular and Molecular Biology, Lab Safety, and Organic Chemistry. The database is part of the Journal of Visualized Experiments (JoVE), a PubMed-indexed video journal. (NIH/NCI-F)
  • JSTOR - The JSTOR Digital Archive includes more than 600 leading academic journals in the humanities, social sciences, and sciences available for NIH & NCI-F users.(NIH/NCI-F)





  • Lexicomp Online - Access content sets and clinical tools that provide users with clinical drug information.  Tools include Trissel's™ 2 Clinical Pharmaceutics Database, interaction analysis, drug identification, patient education resources, calculators, drug comparisons, drug reports, and more. (NIH/NCI-F)
  • LION - See NCI LION (NCI Library Online)


  • MarinLit - A database of marine natural products. (NCI-F only)
  • MedlinePlus - Free to all, a consumer health information service of the National Library of Medicine and the National Institutes of Health.
  • MetaCore - MetaCore is a web-based bioinformatics suite that allows researchers to upload data analysis results from experiments such as microarray, next generation sequencing, metabolic, SAGE, siRNA, microRNA, and screening. It provides functional analysis to identify the most relevant pathways, networks, and cellular processes in the data. Additionally, gene, protein, compound, pathway map, and disease searches are available. The license for the Genomic Analysis Tool is included for studying genetic variance and is particularly useful for studying a set of variants resulting from next generation sequencing experiments. Access requires a user account which is linked to your NIH email address. Sign up on the MetaCore registration(NIH/NCI-F)
  • MetaDrug - (About MetaDrug) The NCI-F Scientific Library has added the MetaDrug tool (NCI-F only) to those already made available by NCI Bethesda to all NIH researchers, GeneGo, MetaCore, MetaRodent. MetaDrug is a platform that can help you predict possible Indications, Modes of Action, ADME, Phase I and Phase II metabolites, and Toxicities of novel compounds. It also allows you to view the predicted activities on pathway maps that can be validated by uploading experimental data for the compounds, once available. For an account to access MetaDrug contact Alan Doss, 301-846-6249, (NCI-F only)
  • MetScape Plugin for Cytoscape - Provides a bioinformatics framework for the visualization and interpretation of metabolomic and expression profiling data in the context of human metabolism. It allows users to build and analyze networks of genes and compounds, identify enriched pathways from expression profiling data, and visualize changes in metabolite data. Gene expression and/or compound concentration data can be loaded from file(s) (in CSV, TSV, or Excel formats), or the user can directly enter individual compounds/genes (using KEGG compound IDs, or Entrez Gene IDs) to build metabolic networks without loading a file. MetScape uses an internal relational database stored at NCIBI that integrates data from KEGG and EHMN.
  • Micromedex - The industry standard for more than 40 years, Micromedex Solutions provide hospitals and healthcare providers with a single source of clinical information — from need-to-know drug, pediatric, disease, lab, and toxicology information to comprehensive resources for patient and consumer education. (NIH/NCI-F)
  • Molecular Imaging and Contrast Agent Database (MICAD) - MICAD is a free source of scientific information regarding molecular imaging and contrast agents (under development, in clinical trials or commercially available for medical applications) that have in vivo data (animal or human) published in peer-reviewed scientific journals. MICAD was established as a key component of the 'Molecular Libraries and Imaging" program of the NIH Common Fund (formerly NIH Roadmap), a set of inter-agency initiatives accelerating medical research. After June 30, 2013, new and revised chapters will no longer be uploaded to the MICAD website. However, the current chapters remain available online via PubMed.
  • Mouse Genome Informatics (MGI) Database - MGI, developed at the Jackson Laboratory in Bar Harbor, Maine, provides free, publicly available access to integrated data on the genetics, genomics and biology of the laboratory mouse.



  • Natural Medicines - Merging Natural Medicines Comprehensive Database and Natural Standard, an authoritative resource on dietary supplements, natural medicines, and complementary alternative and integrative therapies. (NIH/NCI-F)
  • NCBI BioSystems Database - Biological pathways databases which can be searched directly or accessed via links from Entrez Gene, Protein, PubChem Compound, and more.
  • NCI at Frederick Scientific Publications Database (formerly NCI at Frederick-in-Print) - This database is a collection of citations for journal articles authored by employees and contractors of the NCI-F from 1997 through the present. Please bear in mind that this new product is a work in progress, and we welcome any comments you may have.
  • NCI Datasets and Databases - For finding datasets and databases related to cancer research.
  • NCI GDC (Genomic Data Commons) Data Portal - The GDC Data Portal is a robust data-driven platform that allows cancer researchers and bioinformaticians to search and download cancer data for analysis.
  • NCI Online Library -  (formerly NCI LION), from the NCI Library in the Office of Communications and Public Liaison (OCPL), is a repository and alerting service for NCI electronic resources, books, journals, NCI archival materials, and Internet links and content, including back issues of Cancer Letter with full-text article links.  
  • NIH OVID Databases - Includes Books@OVID and Journals@OVID Full Text. No login required; click on Start OvidSP if you are on a login page. Please Logoff after each session. (NIH/NCI-F)
  • NIH Record Archives- The NIH Record, founded in 1949, is the biweekly newsletter for employees of the National Institutes of Health.
  • NIH RePORTER - Formerly known as CRISP, the information found in NIH RePORTER is drawn from eRA databases, Medline, PubMed Central, the NIH Intramural Database, and iEdison, using newly-formed linkages among the disparate data sources. The comprehensiveness of these databases varies, as does the quality of the linkages formed among them. The quality of RePORTER data should improve over time as a result of changes in both data collection (e.g., implementation of the NIH Public Access policy) and the increased ability to identify missing information that comes from making these data accessible to more people. (NIH/NCI-F)



  • OpenHelix - OpenHelix is a partly public, partly fee-based portal that assists researchers in conducting breakthrough research directing scientists to the most relevant publicly available bioinformatics and genomics resources on the web, and then gives them immediate access to tutorials, training materials, and useful tips and information developed by OpenHelix. Only the section of the portal that is publicly available can be accessed effective 2012.
  • Organohalogen Compounds Database - Archives short papers presented at annual Dioxin Symposia from 1990 to date. Sponsored by the nonprofit group, Dioxin 20XX, of the International Advisory Board of the International Symposium of Halogenated Persistent Organic Pollutants (POPs), this free database includes scientific papers in PDF format and covers POPs as they relate to disciplines such as molecular biology, human health risk assessment, management risk assessment, and environmental and analytical chemistry.
  • OverDrive - Access a collection of popular science E-books and audiobooks either online or on your own device. More details and support information.  (NIH/NCI-F)



  • Partek Genomics Suite (Software) - A comprehensive suite of advanced statistics and interactive data visualization specifically designed to reliably extract biological signals from noisy data. Designed for high-dimensional genomic studies containing thousands of samples, it is fast, memory efficient and will analyze large data sets on a personal computer. It supports a complete workflow including convenient data access tools, identification and annotation of important biomarkers, and construction and validation of predictive diagnostic classification systems. The software is Affymetrix GeneChip-compatibleT for gene expression analysis, exon expression analysis, and chromosomal copy number analysis. Access Information: Contact the NIH Help Desk at 301-496-4357 (6:00 am - 6:00 pm); or the NIH IT Service Desk.(NIH/NCI-F)
  • PATAI's Chemistry of Functional Groups - For the organic chemist, searchable database containing all 21 volumes of Patai's series published from 1996 to present. New content, initially 2 volumes per year, will be added. (NIH/NCI-F)
  • Pathway Studio Software (Elsevier) - NCI researchers (includes NCI-F) have unlimited access to the latest version of Elsevier's Pathway Studio software with the Mammalian (protein-centric) knowledge base as well as the premium DiseaseFx (disease-centric) and ChemEffect (compound-centric) knowledge bases, as well as the MedScan text mining module. Researchers also have access to the NCI's high-quality HyNet Yeast 2-Hybrid Protein Interaction Database. The knowledge bases include molecular facts retrieved from Elsevier's journals as well as facts retrieved from articles from other leading scientific publishers and from PubMed abstracts. Pathway Studio lets molecular biologists work in an interactive graphical environment to connect findings from independent research projects, analyze experimental data, and to develop new findings and publish. Frederick Support: NCI investigators located in Frederick are asked to utilize the DMS Help Desk for all Pathway Studio issues. Service requests submitted to DMS Help Desk for software registration should be directed to (NCI/NCI-F)
  • PubChem - PubChem provides information on the biological activities of small molecules. It is a component of NIH's Molecular Libraries Roadmap Initiative.
  • PubMed @ NCIF | FAQ - Use the 'PubMed @ NCIF' link to view the Scientific Library's 'Full-Text' and 'Print' icons while searching PubMed. PubMed is a free version of MEDLINE with access to an index of biomedical literature journals from 1950 forward, as well as a growing collection of free reference books [NCBI Bookshelf] that can be searched by keyword within the PubMed interface.
  • PubMed Central (PMC) - PMC is the NLM's digital archive of biomedical and life sciences journal literature, which is free and accessible on the web, in keeping with NLM's mandate to preserve the biomedical literature. PMC is also a repository for journal literature deposited by participating publishers and for author manuscripts submitted in compliance with NIH's Public Access Policy mandate. Read more about PMC and the mandate at More information about the PMC Manuscript Submission System is available at



  • Reaxys - (References from 1771-; Patents from 1803-). Formerly known as Beilstein, contains enhanced access to Beilstein, Gmelin and Patent Chemistry databases. Reaxys connects validated experimental data from the three authoritative sources and provides workflow tools designed to support planning optimization in chemistry and related disciplines such as pharmacology, toxicology and ecology. It contains specific bioassay results, logPs, toxicity values, and other valuable data. To learn more about Reaxys, or view online training, click on links from within the Reaxys site. If you need any assistance using this database, please feel free to call Alan Doss at x6249 or via email(NIH/NCI-F)
  • RePORT (Research Portfolio Online Reporting Tools) - Provides access to reports, data and analysis of NIH research activities including information on NIH expenditures and the results of NIH-funded research. For questions and comments, please contact the RePORT team.



  • SciBX - Science-Business eXchange - A weekly publication that provides a timely, concise and understandable analysis of the scientific content and commercial potential of the most important translational research papers from across the life science literature. Editorial teams at SciBX mine articles across the literature each week, distilling information down to 25 most important developments. By reporting the industry viewpoint on key papers, SciBX provides a unique scientific and commercial perspective on today's breakthrough science.(NIH/NCI-F)
  • ScienceDirect Database - Link to the main page of ScienceDirect's electronic collection of full-text science, technology, medical journals and books and bibliographic information; you can also find a wide variety of other features and content. (NIH/NCI-F)
  • SciFinder - As of 6/2012, access through accounts administered by the NIH Library. For further information, visit the SciFinder Registration page from the NIH Library. (NIH/NCI-F)
  • Sciwheel - (formerly F1000 Workspace) is a workspace for scientists to collect, write and discuss scientific literature. Powered by a faculty of over 10,000 leading experts in biology and medicine. (NIH/NCI-F)
  • SCOPUS - An abstract and indexing database from Elsevier Science, Scopus, offers access to thousands of peer-reviewed titles from more than 7,000 international publishers covering scientific, technical, medical, and social science literature. In Scopus, you can set up an email alert to let you know each time a particular article of interest is cited in Scopus. (NIH/NCI-F)
  • search.bioPreprint - A tool to help refine preprint searches via Topic Clusters to discover cutting edge, yet-to-be published or peer-reviewed biomedical research articles retrieved from Europe PMC.  Article
  • SEER Cancer Statistics Review (CSR) - (1975-2016). The SEER Cancer Statistics Review (CSR), a report of the most recent cancer incidence, mortality, survival, prevalence, and lifetime risk statistics, is published annually by the Surveillance Research Program of the NCI.
  • Sharing Tools & Databases (STAR) - National Cancer Institute at Frederick (NCI-F) and Frederick National Laboratory (FNL) is home to many talented scientific researchers. This site is dedicated to them, and to their research, and is open to all NCI-F researchers who wish to share the fruits of their research with the rest of NCI-F, as well as with a larger, world-wide community of researchers, in the spirit of collaboration that moves research forward and makes breakthroughs more likely to happen. Please contact the Scientific Library for more information on how you can have your research represented on this site.
  • Springer Nature Experiments (formerly Springer Protocols) - Full-text access to over 60,000 online biomedical research protocols and methods from Methods in Molecular Biology (1984-),Methods in Molecular Medicine (1996-), content found in Neuromethods, Methods in Pharmacology and ToxicologyMethods in Biotechnology, and more. Access individual titles in Springer Nature Experiments from the Catalog using either the Series title or the unique volume title. (NIH/NCI-F)
  • STAT!Ref - A full-text healthcare library with over 600 titles in over 50 healthcare disciplines. Also utilize EBMcalc, a digital medical reference and tool set including medical formulae, clinical criteria sets and decision tree analysis tools used everyday by clinicians, medical educators, nurses and health care students.(NIH/NCI-F)
  • STITCH - The Search Tool for Interactions of Chemicals ( STITCH ) is a resource to explore known and predicted interactions of chemicals and proteins. Chemicals are linked to other chemicals and proteins by evidence derived from experiments, databases and the literature. Read articles from Nucleic Acids Research about STICH: Article 1Article 2.



  • Taylor & Francis Group Ebooks (formerly called "CRCnetBASE") - Subscribed items in Library's collection also available individually by title via OneSearch on the Library's homepage. (NCI-F only)
  • TOXMAP (Environmental Health E-Maps) - TOXMAP is a Geographic Information System (GIS) from the National Library of Medicine that uses maps of the United States to help users visually explore data from the US Environmental Protection Agency (EPA)'s Toxics Release Inventory (TRI) and Superfund Program.
  • TOXNET - from NLM, the NLM Toxicology Data Network, databases on toxicology, hazardous chemicals, environmental health, and toxic release.
  • TRANSFAC + PROTEOME Professional – Can be used for the identification of Experimentally Demonstrated Regulators for Eukaryotic cells, visualization of a gene’s promoter region and associated regulatory features, identification of experimentally demonstrated targets of transcription factors, predicted binding sites for a gene of interest, and analysis of microarray, ChiP-Seq, and RNA-seq data. Before accessing this resource, first setup an account at the Registration Site, using the following License Key: 1881-6975-97565225. Quick Start Guide, Video and Other Tutorials. (NIH/NCI-F)



  • UpToDate - An evidence-based tool for answering clinical questions and identifying treatments with over 75,000 pages of peer-reviewed text, written and reviewed by clinicians. (NIH/NCI-F)
  • UCSC Genome Browser - Contains the reference sequence and working draft assemblies for a large collection of genomes; also provides portals to the ENCODE and Neandertal projects. Online TutorialsOnline Seminars.




  • Web of Science (WOS) - Online version of ISI's Science Citation Index Expanded (1900 - present) & Social Sciences Citation Index, (1900 - present); with "Cited Reference Search," a unique tool for citation reference searching. WOS Interface also includes BIOSIS Citation Index; Current Contents Index; Data Citation Index; Derwent Innovations Index; InCites; MEDLINE®; Russian Science Citation Index; SciELO Citation Index; and Zoological Record. Make your selection from the WOS Core Collection pulldown list. Also available from the WOS site are links to Journal Citation Reports and EndNote Online. (NIH/NCI-F)








Date Last Updated: 5/2/2022