HIV Conference to Be Held on October 21 at NCI at Frederick

Anne Arthur
HIV image

By Anne Arthur, Guest Writer

The HIV Drug Resistance Program Conference on “Virus Structure: Putting the Pieces Together” will be held at NCI at Frederick on October 21, 2014, from 1:00 to 5:45 p.m. in the Conference Center auditorium, Building 549.

The HIV Drug Resistance Program, Center for Cancer Research, is hosting this half-day conference to showcase the latest findings on the structural biology of viruses, with a particular emphasis on imaging macromolecular structures and deciphering how viral and host proteins interact to mediate pathogenesis. Exploring new technologies that enhance the sensitivity of imaging systems will provide valuable information about the structure and dynamics of macromolecular assemblies to aid the design of more effective antiviral therapies.


1:00–1:10 p.m. Stephen Hughes, Director, HIV DRP
Welcoming remarks
1:10–1:50 p.m. Joseph Sodroski (Dana-Farber Cancer Institute)
Structural mechanisms of HIV-1 resistance to entry inhibitors
1:50–2:30 p.m. Owen Pornillos (University of Virginia)
Molecular recognition of the HIV-1 capsid
2:30–3:10 p.m. Michael F. Summers (HHMI/University of Maryland, Baltimore County)
Insights into the structural basis and mechanism of HIV-1 genome packaging
3:10–3:40 p.m. Break
3:40–4:20 p.m. Erica Ollmann Saphire (The Scripps Research Institute)
The molecular tool-kit of viral hemorrhagic fevers
4:20–5:00 p.m. Jacek Skowronski (Case Western Reserve University)
Restriction factors targeted by lentiviral Vpx and Vpr
5:00–5:40 p.m. Angela Gronenborn (University of Pittsburgh)
HIV capsid and interactions
5:40–5:45 p.m. Stephen Hughes 
Closing remarks

Additional information about the conference is available at

Anne Arthur is the technical laboratory manager, HIV Drug Resistance Program.