Tucked away among NCI at Frederick’s various buildings, two facilities are quietly under development. In one, engineers are assembling a hulking Titan Krios electron microscope. In the other, equipment is slowly but surely being gathered for eventual installation. The microscope belongs to the newly minted Center for Structural Biology, formed from a merger of the Macromolecular Crystallography Laboratory and the Structural Biology Laboratory. It is the first of Thermo Fisher Scientific’s latest line of Krios microscopes to be installed outside of one of the company’s factories.
From April 4–10, the Scientific Library invites you to celebrate National Library Week. This year’s theme is “Welcome to Your Library.” The Scientific Library staff is eager to greet you when in-person operations resume, but in the interim, they welcome you to explore the many services that continue beyond the four walls of the Library’s locations in Building 549 and at the Advanced Technology Research Facility.
The National Cancer Institute is currently supporting more than 6,700 clinical trials. That staggering statistic is dwarfed by the number of participants in those trials, many of whom are cancer patients. Even more astounding is that these numbers are for just this moment in time. The thousands of trials currently recruiting or underway are themselves a mere fraction of the studies NCI has conducted or supported since its creation in 1937.
Used successfully in several industries, digital twins have the potential to forge a path toward advances in cancer care and research. Frederick National Laboratory is a lead organization in the strategic interagency collaboration between the National Cancer Institute and the U.S. Department of Energy and has been instrumental in the development of innovative technologies for creating a cancer patient digital twin.
Researchers in the National Cancer Institute’s Center for Cancer Research (CCR) and the Frederick National Laboratory’s Basic Science Program have discovered molecules that could keep the body from working against a cancer treatment.
Unsurprisingly, the new Basic Research Program at the Frederick Cancer Research Center took some time to gain momentum despite the preparations that had been made. Margaret Kripke, Ph.D., head of the program’s Immunobiology of Physical and Chemical Carcinogenesis Section at the time, recalls that her first year was dedicated to setting up her new laboratory, hiring staff, moving around, and finishing projects she had started in her former laboratory at University of Utah.
The Scientific Library recently hosted its first virtual discussion of 2021, featuring Yvonne A. Evrard, Ph.D., operations manager for the NCI Patient-Derived Models Repository at NCI at Frederick and the Frederick National Laboratory for Cancer Research. These virtual discussions are one way the Library uses its position as a research information hub to engage scientific researchers through collaboration, interaction, and discussion.
By early 1974, the concept of the first investigator-initiated research program in Frederick was firmly approved. The idea had passed through the necessary channels, and the National Cancer Institute and the Frederick Cancer Research Center set about making it a reality.
As the winter of 1973 turned to spring, the Frederick Cancer Research Center (FCRC), the forerunner to the Frederick National Laboratory and the National Cancer Institute (NCI) at Frederick that exist today, neared the one-year mark since its opening. The more than 250 employees had made sound progress, given the challenges of converting the old Fort Detrick biowarfare facilities into a fledgling cancer center. Their efforts had drawn some attention, too.
As the pandemic has forced many people to work from home or cancel their plans, the Werner H. Kirsten (WHK) interns have been no exception. Every year, NCI at Frederick and Frederick National Laboratory welcome a new group of high school seniors as interns through the WHK Student Intern Program. The students participate in a yearlong internship under the wing of a mentor in either a research area or administrative area in support of research.