A Paradox and Alan Rein: Distinguished Retrovirologist Retires from the HIV DRP

Early in the COVID-19 pandemic, before vaccines were available and while SARS-CoV-2 was wreaking havoc worldwide, Barry O’Keefe, Ph.D., and longtime collaborators in Brazil and Spain pooled their knowledge and resources to study cyanovirin-N (CV-N), a protein from cyanobacteria, photosynthetic bacteria commonly known as blue-green algae. O’Keefe had a hunch it could be developed to fight the spread of SARS-CoV-2.

Former Werner H. Kirsten (WHK) Student Intern Program participant Lea Jih-Vieira followed a narrow path of interest and discovered a plethora of possibilities.

In the vermilion-gold light of a humid June morning, groups of visitors fanned out across the NCI Frederick campus. Most weren’t scientists—not yet, at least. Still, they entered laboratories and work areas, though it quickly became apparent that some were barely tall enough to see over the lab countertops. That didn’t stop them from trying.

The Werner H. Kirsten (WHK) program, a long-standing institution in Frederick, recently graduated its 32nd class. This unique internship opportunity continues to catapult many high school seniors on the path to STEM careers. Before the 2023 WHK student interns concluded their internships, WHK Program Manager Carrie Wagerman wanted to ensure they were recognized for their achievement in completing the rigorous program.

In the Natural Products Branch, projects demand a level of precision that makes Cinderella’s slipper look like child’s play. However, lab equipment isn’t always tailor-made for such uniqueness, sometimes requiring a little modification with special parts to get the job done. Sometimes those parts aren’t available. It rightly sounds like a headache, but Jason Evans and Matthew Harris say the group regularly pulls it off—at times, even in as little as a day.