Platinum Publications, April 28–May 31, 2017

Platinum Publications

Platinum Publications are selected from articles by NCI at Frederick scientists published in 42 prestigious science journals. This list represents articles published during the time period shown above, as generated from PubMed.

Articles designated as Platinum Highlights are noteworthy articles selected from among the most recently published Platinum Publications. The Scientific Library maintains the NCI at Frederick Scientific Publications database, a collection of citations for journal articles authored by NCI at Frederick employees since 1997. 

- Denotes Platinum Highlight article. Click on the image to go to the Platinum Highlight article.
 



AIDS RESEARCH AND HUMAN RETROVIRUSES

Martins MA, Tully DC, Shin YC, Gonzalez-Nieto L, Weisgrau K, Bean DJ, Gadgil R, Gutman MJ, Domingues A, Maxwell HS, Magnani D, Ricciardi M, Pedreno-Lopez N, Bailey V, Cruz M, Lima NS, Bonaldo M, Altman J, Rakasz E, Capuano S, Reimann K, Piatak M, Lifson J, Desrosiers R, Allen T, Watkins D. Rare Control of SIVmac239 Infection in a Vaccinated Rhesus Macaque. AIDS Res Hum Retroviruses 2017.


CANCER RESEARCH

Holbeck SL, Camalier R, Crowell JA, Govindharajulu JP, Hollingshead MG, Anderson LW, Polley EC, Rubinstein L, Srivastava AK, Wilsker DF, Collins JM, Doroshow JH. The National Cancer Institute ALMANAC: A Comprehensive Screening Resource for the Detection of Anticancer Drug Pairs with Enhanced Therapeutic Activity. Cancer Res 2017.


CELL CHEMICAL BIOLOGY

Fernandez MV, Freed EO. "Expand and Click": A New Method for Labeling HIV-1 Envelope Glycoproteins. Cell Chem Biol 24(5):548-550, 2017.

Li X, Nelson CG, Nair RR, Hazlehurst L, Moroni T, Martinez-Acedo P, Nanna AR, Hymel D, Burke TR, Jr., Rader C. Stable and Potent Selenomab-Drug Conjugates. Cell Chem Biol 24(4):433-442.e6, 2017.


JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

Marciano BE, Zerbe CS, Falcone EL, Ding L, DeRavin SS, Daub J, Kreuzburg S, Yockey L, Hunsberger S, Foruraghi L, Barnhart LA, Matharu K, Anderson V, Darnell DN, Frein C, Fink DL, Lau KP, Long Priel DA, Gallin JI, Malech HL, Uzel G, Freeman AF, Kuhns DB, Rosenzweig SD, Holland SM. X-linked Carriers of Chronic Granulomatous Disease: Illness, Lyonization and Stability. J Allergy Clin Immunol 2017.


JOURNAL OF CLINICAL INVESTIGATION

Nayar U, Sadek J, Reichel J, Hernandez-Hopkins D, Akar G, Barelli PJ, Sahai MA, Zhou H, Totonchy J, Jayabalan D, Niesvizky R, Guasparri I, Hassane D, Liu Y, Sei S, Shoemaker RH, Warren JD, Elemento O, Kaye KM, Cesarman E. Identification of a nucleoside analog active against adenosine kinase-expressing plasma cell malignancies. J Clin Invest 127(6):2066-2080, 2017.


JOURNAL OF MEDICINAL CHEMISTRY

Scott JD, DeMong DE, Greshock TJ, Basu K, Dai X, Harris J, Hruza A, Li SW, Lin SI, Liu H, Macala MK, Hu ZY, Mei H, Zhang HL, Walsh P, Poirier M, Shi ZC, Xiao L, Agnihotri G, Baptista MAS, Columbus J, Fell MJ, Hyde LA, Kuvelkar R, Lin YH, Mirescu C, Morrow JA, Yin ZZ, Zhang XP, Zhou XP, Chang RK, Embrey MW, Sanders JM, Tiscia HE, Drolet RE, Kern JT, Sur SM, Renger JJ, Bilodeau MT, Kennedy ME, Parker EM, Stamford AW, Nargund R, McCauley JA, Miller MW. Discovery of a 3-(4-Pyrimidinyl) Indazole (MLi-2), an Orally Available and Selective Leucine-Rich Repeat Kinase 2 (LRRK2) Inhibitor that Reduces Brain Kinase Activity. J Med Chem 60(7):2983-2992, 2017.


JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Nicolaou KC, Rhoades D, Wang Y, Bai R, Hamel E, Aujay M, Sandoval J, Gavrilyuk J. 12,13-Aziridinyl Epothilones. Stereoselective Synthesis of Trisubstituted Olefinic Bonds from Methyl Ketones and Heteroaromatic Phosphonates and Design, Synthesis, and Biological Evaluation of Potent Antitumor Agents. J Am Chem Soc 139(21):7318-7334, 2017.


JOURNAL OF VIROLOGY

Dilley KA, Nikolaitchik OA, Galli A, Burdick RC, Levine L, Li K, Rein A, Pathak VK, Hu WS. Interactions Between HIV-1 Gag and Viral RNA Genome Enhance Virion Assembly. J Virol 2017.

Julg B, Pegu A, Abbink P, Liu J, Brinkman A, Molloy K, Mojta S, Chandrashekar A, Callow K, Wang K, Chen X, Schmidt SD, Huang J, Koup RA, Seaman MS, Keele BF, Mascola JR, Connors M, Barouch DH. Virological control by the CD4-binding site antibody N6 in SHIV-infected rhesus monkeys. J Virol 2017.


METHODS IN MOLECULAR BIOLOGY

Lawrence SM, Golubeva YG. Optimization of Immunostaining for Prospective Image Analysis. Methods Mol Biol 1606235-263, 2017.

Raran-Kurussi S, Cherry S, Zhang D, Waugh DS. Removal of Affinity Tags with TEV Protease. Methods Mol Biol 1586221-230, 2017.

Taylor T, Denson JP, Esposito D. Optimizing Expression and Solubility of Proteins in E. coli Using Modified Media and Induction Parameters. Methods Mol Biol 158665-82, 2017.


MOLECULAR AND CELLULAR BIOLOGY

Choi SE, Kwon S, Seok S, Xiao Z, Lee KW, Kang Y, Li X, Shinoda K, Kajimura S, Kemper B, Kemper JK. Obesity-linked phosphorylation of SIRT1 by CK2 inhibits its nuclear localization and promotes fatty liver. Mol Cell Biol 2017.


NATURE IMMUNOLOGY

Afzali B, Gronholm J, Vandrovcova J, O'Brien C, Sun HW, Vanderleyden I, Davis FP, Khoder A, Zhang Y, Hegazy AN, Villarino AV, Palmer IW, Kaufman J, Watts NR, Kazemian M, Kamenyeva O, Keith J, Sayed A, Kasperaviciute D, Mueller M, Hughes JD, Fuss IJ, Sadiyah MF, Montgomery-Recht K, McElwee J, Restifo NP, Strober W, Linterman MA, Wingfield PT, Uhlig HH, Roychoudhuri R, Aitman TJ, Kelleher P, Lenardo MJ, O'Shea JJ, Cooper N, Laurence ADJ. BACH2 immunodeficiency illustrates an association between super-enhancers and haploinsufficiency. Nat Immunol 2017.


PLOS PATHOGENS

Feder AF, Kline C, Polacino P, Cottrell M, Kashuba ADM, Keele BF, Hu SL, Petrov DA, Pennings PS, Ambrose Z. A spatio-temporal assessment of simian/human immunodeficiency virus (SHIV) evolution reveals a highly dynamic process within the host. PLoS Pathog 13(5):e1006358, 2017.

Fennessey CM, Pinkevych M, Immonen TT, Reynaldi A, Venturi V, Nadella P, Reid C, Newman L, Lipkey L, Oswald K, Bosche WJ, Trivett MT, Ohlen C, Ott DE, Estes JD, Del Prete GQ, Lifson JD, Davenport MP, Keele BF. Genetically-barcoded SIV facilitates enumeration of rebound variants and estimation of reactivation rates in nonhuman primates following interruption of suppressive antiretroviral therapy. PLoS Pathog 13(5):e1006359, 2017.


RETROVIROLOGY

Monde K, Terasawa H, Nakano Y, Soheilian F, Nagashima K, Maeda Y, Ono A. Molecular mechanisms by which HERV-K Gag interferes with HIV-1 Gag assembly and particle infectivity. Retrovirology 14(1):27, 2017.