Science

Digital Twins for Cancer Care: Exploring a Cross-disciplinary Innovative Approach

Used successfully in several industries, digital twins have the potential to forge a path toward advances in cancer care and research. Frederick National Laboratory is a lead organization in the strategic interagency collaboration between the National Cancer Institute and the U.S. Department of Energy and has been instrumental in the development of innovative technologies for creating a cancer patient digital twin.

Virtual Discussion Features the NCI Patient-Derived Models Repository

The Scientific Library recently hosted its first virtual discussion of 2021, featuring Yvonne A. Evrard, Ph.D., operations manager for the NCI Patient-Derived Models Repository at NCI at Frederick and the Frederick National Laboratory for Cancer Research. These virtual discussions are one way the Library uses its position as a research information hub to engage scientific researchers through collaboration, interaction, and discussion.

Clones complicate a cure and pose problems for people with HIV

A new advance in our understanding of HIV comes from what Steve Hughes, Ph.D., calls “an odd observation.” Certain people living with HIV had only partially suppressed levels of virus in their blood despite being on effective antiretroviral therapy (drugs used to manage HIV). At first, an explanation seemed like it would be simple—but it wasn’t.

Virtual Discussion Panel Highlights Electron Microscopy Services

The Scientific Library recently hosted a discussion panel on electron microscopy services at the National Cancer Institute (NCI) at Frederick and Frederick National Laboratory for Cancer Research (FNL), its third panel of 2020. This Electron Microscopy Discussion Panel brought together specialists from the Electron Microscopy Laboratory, the Center for Molecular Microscopy, and the National Cryo-Electron Microscopy Facility.

2020 Technology Showcase brings NCI and FNL technologies to a new audience

The 2020 Technology Showcase welcomed more than 300 viewers for half a day of presentations and panels on technology commercialization and collaboration. The annual event once again highlighted the capabilities of the Frederick National Laboratory for Cancer Research, National Cancer Institute, and greater Frederick region—but this year, with its novel virtual format, it reached new audiences.

Sequencing Facility Uses Cutting-Edge Technology to Make the Old New Again

Just a few years ago, it was difficult to get any meaningful sequence data from formalin-fixed, paraffin-embedded patient tissue samples. These biopsy specimens, which are tissues preserved in formaldehyde and embedded in wax for storage, are easy to make and store, even in remote research locations. Many are available, and more are made all the time, for use in experimental research and drug development. Because there are so many samples that have been taken over numerous years, they can also be used to help study the evolution of diseases and viruses.