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Early in the COVID-19 pandemic, before vaccines were available and while SARS-CoV-2 was wreaking havoc worldwide, Barry O’Keefe, Ph.D., and longtime collaborators in Brazil and Spain pooled their knowledge and resources to study cyanovirin-N (CV-N), a protein from cyanobacteria, photosynthetic bacteria commonly known as blue-green algae. O’Keefe had a hunch it could be developed to fight the spread of SARS-CoV-2.

Former Werner H. Kirsten (WHK) Student Intern Program participant Lea Jih-Vieira followed a narrow path of interest and discovered a plethora of possibilities. When she first learned about the WHK internship from an information session at her high school, Jih-Vieira wasn’t sure about applying because it seemed geared toward laboratory work, which didn’t capture her interest. But, with some encouragement from her mom, Jih-Vieira applied and was accepted for an internship with NCI Frederick’s Office of Scientific Operations (OSO).

In the vermilion-gold light of a humid June morning, groups of visitors fanned out across the NCI Frederick campus. Most weren’t scientists—not yet, at least. Still, they entered laboratories and work areas, though it quickly became apparent that some were barely tall enough to see over the lab countertops. That didn’t stop them from trying.

The Werner H. Kirsten (WHK) program, a long-standing institution in Frederick, recently graduated its 32nd class. This unique internship opportunity continues to catapult many high school seniors on the path to STEM careers. Before the 2023 WHK student interns concluded their internships, WHK Program Manager Carrie Wagerman wanted to ensure they were recognized for their achievement in completing the rigorous program. She asked them to share a little about themselves, their plans for the future, and some takeaways from their experience. Read their responses below.

In the Natural Products Branch, projects demand a level of precision that makes Cinderella’s slipper look like child’s play. However, lab equipment isn’t always tailor-made for such uniqueness, sometimes requiring a little modification with special parts to get the job done. Sometimes those parts aren’t available. It rightly sounds like a headache, but Jason Evans and Matthew Harris say the group regularly pulls it off—at times, even in as little as a day.

After 32 years with the National Cancer Institute, Tom Stackhouse, Ph.D., is riding into the sunset. The director of the Technology Transfer Center retires at the end of June. He’s gratified to have had a fulfilling career that helped enable so many partnerships, programs, and products. The team has had several successes, including some in support of the science in Frederick.

Three scientists from the region presented innovative imaging techniques and discussed how they are leveraging them to advance cancer research and ultimately improve human health at the Biotech Connector seminar on Wednesday, May 17, the second in this year’s series sponsored by the Frederick National Laboratory for Cancer Research and the Frederick County Chamber of Commerce. 

A new drug and vaccine delivery method that utilizes synthetic bacterial nanoparticles could improve chemotherapy treatments, and a groundbreaking alternative to drilled wells may soon be breaking ground in agricultural areas. The Federal Laboratory Education Accelerator and the work of Master of Business Administration students across the country are helping move these and other far-ranging technologies out of the laboratory and into the market.

A hawk circles high above NCI Frederick. A blackbird hops along a steam pipe, its talons clicking on the metal. Sparrows flit from tree to tree. Geese are gathered on the grass. Birds are regular visitors to NCI Frederick, and thanks to a months-long project, some now have a better chance to make the campus their home this spring.

The curtain has officially dropped on the Spring Research Festival for another year. With its signature vendor show, poster display, and bevy of lectures, the hybrid event looked much as it did in pre-pandemic times. Yet among the participants, there was an unmistakable impression of eagerness, a recognition of opportunity.