NCI and FNL Researchers Turn Lessons Learned into Stepping Stones

Imagine you’re building a dresser. You find all the wood and hardware you need and have the instructions, the right tools, and a team of professionals to help. As you and your team put it together, you realize that while the frame is solid, the drawers don’t open and close correctly. You might be tempted to feel discouraged by the results. But a group of scientists from the National Cancer Institute (NCI), Frederick National Laboratory for Cancer Research (FNL), and other collaborating institutions share a different perspective in their recent work published in PNAS. They weren’t trying to assemble furniture but rather generate a new, better mouse model of the most common kidney cancer, clear cell renal cell carcinoma (ccRCC).
Karolina Wilk, Editor, Staff Writer
 04.29.2025
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In the News

Science & Technology | New Approach for Producing and Purifying IL-15 Heterodimers That Have Potent Immune Effect

Cytokines are proteins that play a crucial role in the human immune system by delivering messages that trigger the activation of immune cells to fight off attacks from viruses or other invaders. Cristina Bergamaschi, Ph.D., NCI Center for Cancer Research, has been studying the mechanism of expression and function of a cytokine known as interleukin-15 (IL-15) for the last five years, in collaboration with Elena Chertova, Ph.D., and other researchers in the Retroviral Protein Chemistry Core of the AIDS and Cancer Virus Program, Frederick National Laboratory for Cancer Research.
By Nancy Parrish, Staff Writer 11.25.2013
Science & Technology Publications Platinum Highlight November 2013

Community | Leidos Reclaims Defelice Cup at Annual Golf Tournament

Leidos Biomedical Research reclaimed the Defelice Cup trophy from NCI at the eighth annual Ronald H. Defelice golf tournament, held October 14. The final score was 15–7, with Leidos Biomed tying the series 4 to 4. Fourteen players on each team battled it out at Rattlewood golf course in Mount Airy, Md.
By Ashley DeVine, Staff Writer 11.15.2013
Community Events People November 2013

Community | NCI and Leidos Play Ball

The ping of an aluminum bat off a ball or the thump of a pop-up fly ball caught in a glove are two sounds familiar to baseball fans. Slow-pitch softball sounds—like those in the August game between mixed teams of NCI and Leidos Biomedical Research (formerly SAIC-Frederick) players—are similar.
By Carolynne Keenan, Contributing Writer 11.15.2013
Community Events People November 2013

Scientific Library | OneSearch Gives You Access to More Than 7,000 Publishers and Content Providers

OneSearch, an exciting new resource from the Scientific Library, is now available to the NCI at Frederick community. This new resource provides a quick and easy way to search multiple Scientific Library resources and collections using a single search box for journal articles, books, media, and more. A large central index is compiled from more than 7,000 publishers and content providers outside the library’s holdings.
By Robin Meckley, Contributing Writer 08.31.2013
Scientific Library August 2013

Students | Students Share Their Research at Student Poster Day

More than 50 Werner H. Kirsten student interns and college interns presented their research at Summer Student Poster Day on August 6 in the Building 549 lobby. Joseph Bergman, a high school intern in the Center for Cancer Research Nanobiology Laboratory, participated in the event “for the opportunity to present my summer research. It allowed me to meet people and get the experience of sharing and explaining my work.”
By Ashley DeVine, Staff Writer 08.31.2013
Students Outreach August 2013