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November 2013

New Approach for Producing and Purifying IL-15 Heterodimers That Have Potent Immune Effect

Cytokines are proteins that play a crucial role in the human immune system by delivering messages that trigger the activation of immune cells to fight off attacks from viruses or other invaders. Cristina Bergamaschi, Ph.D., NCI Center for Cancer Research, has been studying the mechanism of expression and function of a cytokine known as interleukin-15 (IL-15) for the last five years, in collaboration with Elena Chertova, Ph.D., and other researchers in the Retroviral Protein Chemistry Core of the AIDS and Cancer Virus Program, Frederick National Laboratory for Cancer Research.

Novel Vaccine Approach Achieves “Functional Cure” of AIDS Virus in Monkeys

Scientists at the Oregon Health & Science University and the AIDS and Cancer Virus Program of the Frederick National Laboratory for Cancer Research have used a novel vaccine approach to achieve a “functional cure” and apparent eradication of infection with a monkey version of the AIDS virus.

What Does the Employee Diversity Team Have in Store for Fall?

The Employee Diversity Team (EDT) is out and about this fall, making the NCI at Frederick community aware of various cultural traditions and events around Frederick County that employees can participate in. The team is working with staff members of Native American descent to feature a display case and movie selection celebrating Native American Heritage Month in November. The team will keep you informed about Frederick events taking place in November and December. Keep a look out for EDT e-mails.

Leidos Reclaims Defelice Cup at Annual Golf Tournament

Leidos Biomedical Research reclaimed the Defelice Cup trophy from NCI at the eighth annual Ronald H. Defelice golf tournament, held October 14. The final score was 15–7, with Leidos Biomed tying the series 4 to 4. Fourteen players on each team battled it out at Rattlewood golf course in Mount Airy, Md.

NCI and Leidos Play Ball

The ping of an aluminum bat off a ball or the thump of a pop-up fly ball caught in a glove are two sounds familiar to baseball fans. Slow-pitch softball sounds—like those in the August game between mixed teams of NCI and Leidos Biomedical Research (formerly SAIC-Frederick) players—are similar.