Nineteen Patents Issued in 2012 for Inventions by Frederick Researchers

Scientific figure

The figure, representing US Patent 8,198,402 (Smoothened polypeptides and methods of use), illustrates the design principle used for generating the Hedgehog pathway inhibitors disclosed in the patent: folding the inhibitors through an interaction with the cellular membrane.  Membrane anchoring through lipidation allows the membrane to facilitate the folding of short protein fragments and the conversion of these fragments into potent inhibitors of the corresponding protein. Folding the inhibitors into the appropriate conformation is critical to their activity.

By Karen Surabian, Contributing Writer

Patents provide a period of exclusivity and are a way to exclude others from making, using, or selling an inventor’s novel technology. For the National Institutes of Health (NIH), patents are an incentive for an outside party to license, develop, and commercialize NIH technologies that will benefit public health, especially those that require substantial further development by an outside party, such as therapeutics and diagnostics.

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Students Share Their Research at Student Poster Day

Student Poster Day

Students Share Their Research at Student Poster Day 

By Ashley DeVine, Staff Writer

More than 50 Werner H. Kirsten student interns and college interns presented their research at Summer Student Poster Day on August 6 in the Building 549 lobby. 

Joseph Bergman, a high school intern in the Center for Cancer Research Nanobiology Laboratory, participated in the event “for the opportunity to present my summer research. It allowed me to meet people and get the experience of sharing and explaining my work.”

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2013 Student Science Jeopardy Tournament a Big Success

Jeopardy participants

Participants in the seventh annual Student Science Jeopardy Tournament included Pushkar Aggarwal, Janine Bahsali, Joseph Bergman, Harrison Boyce, Colin Burr, Avilash Das, Katie Goetz, Monica Gouzoulis, Nikhil Gowda, Ayush Goyal, Jen Hofmann, Dahlia Kronfli, Edward Liang, Megan Mounts, Theo Nikolaitchik, Swathi Penumutchu, Renee Purtscher, Amil Sahai, Esther Shafer, Madelyne Xiao. The judges were Dina Sigano and Jim Cherry. Some participants were not present for the photo

By Robin Meckley, Contributing Writer

The category was “General Science,” and the clue read: “Named for an Italian scientist, it is the scientific number of molecules in 1 gram mole of any substance.” Everything depended on knowing the correct response and wagering enough points.  

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Women of NCI at Frederick

Women of NCI

By Andrea Frydl, Contributing Writer

Editor’s note: This article has been updated since it was originally posted on August 22, 2013

Each year, the Employee Diversity Team (EDT) acknowledges a group of women for their great achievements and contributions towards the mission of the National Cancer Institute at Frederick.  Details of their achievements and unique personalities were on display in Building 549 in March, and we present a brief summary of each below:

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