Science

Spring Research Festival Sponsored by NICBR for First Time

By Melissa Porter, Staff Writer

For the past 16 years, the annual Spring Research Festival has been sponsored by NCI at Frederick and Fort Detrick to acquaint fellow researchers, students, and the community at large with the important discoveries being made at this facility to fight cancer, AIDS, and other infectious diseases.

Morrison Receives NIH Award for Major Ras/Raf Breakthroughs

By Ashley DeVine, Staff Writer

Deborah Morrison, Ph.D., laboratory chief, Laboratory of Cell and Developmental Signaling, Center for Cancer Research (CCR), received an NIH Director’s Award in June “for major breakthroughs in elucidating the mechanisms of Ras/Raf signaling that will be critical for diagnosis and treatment of disease,” according to the NIH Director’s Awards Ceremony brochure.

She was nominated by Ira Daar, Ph.D., senior investigator, Developmental Signal Transduction Section, Laboratory of Cell and Developmental Signaling, CCR.

IL-27 Found to Play Significant Role in Conferring HIV Resistance

By Nancy Parrish, Staff Writer

The human immunodeficiency virus (HIV) targets specific immune cells in the body known as macrophages because these are the cells that eliminate foreign material such as bacteria or viruses. HIV is able to reproduce and spread throughout the body if it can avoid destruction by macrophages.

A recent study by Lue Dai, Ph.D., and colleagues revealed that the human cytokine IL-27 helps promote the body’s production of macrophages that are resistant to HIV. The study further found that IL-27 suppresses a gene known as SPTBN1, which facilitates the survival of HIV cells. This breakthrough research was recently published in the Journal of Experimental Medicine.

$200,000 Grants Awarded to CCR Researchers for HIV/AIDS Studies

By Nancy Parrish, Staff Writer

Earlier this year, the Office of AIDS Research (OAR) awarded two, two-year grants of $200,000 each to Anu Puri, Ph.D., and Robert Blumenthal, Ph.D., both of the Center for Cancer Research (CCR) Nanobiology Program, and to Eric Freed, Ph.D., of the HIV Drug Resistance Program, for their research on potential new treatments for HIV.

Best Collaborative Publication Announced during Spring Research Festival Week

By Nancy Parrish, Staff Writer

The winner of the 2012 competition for the best collaborative publication was announced on May 7, as part of the lead-up to the Spring Research Festival sponsored by the National Interagency Confederation for Biological Research (NICBR) and the National Cancer Institute at Frederick on May 8 and 9.

FNLCR Set to Launch Full-Scale Assault on Ras

By Frank Blanchard, Staff Writer

Armed with an array of leading-edge technologies, scientific and technical expertise, and the full backing of the National Cancer Institute’s (NCI’s) scientific advisers, the Frederick National Laboratory for Cancer Research (FNLCR) is preparing to launch a full-scale attack against an intractable problem:  the cancer-causing family of Ras genes.

NICBR Announces First Collaboration Project Awards

Courtesy of the NICBR Public Affairs/Community Relations Subcommittee

The National Interagency Confederation for Biological Research (NICBR) announced the 2012 NICBR Collaboration Project Award (CPA) Program winners in December. The award, the first of its kind for NICBR, was adapted from the National Cancer Institute’s (NCI’s) Young Investigator Award Program. This year, the CPA was bestowed to three research projects pertaining to collaborations between NICBR agencies.

Remembering Joseph Mayo and His Contributions to Animal Science

By Carolynne Keenan, Guest Writer

In the 1990s, when Joseph Mayo, D.V.M, ran out of gas leading coworkers home from a meeting in Bethesda, he pulled over to the side of the road on I-270 and waited for help. He didn’t have to wait long; within a few minutes a passing motorist took pity on the group of scientists and offered them a lift back to Fort Detrick.

BDP Is Unified at the ATRF

By Ken Michaels, Staff Writer

The Biopharmaceutical Development Program (BDP) at the Frederick National Laboratory is, for the first time ever, in a single building at the Advanced Technology Research Facility (ATRF).

At Fort Detrick, BDP operations were spread out in about a dozen buildings, resulting in redundancies in maintaining various utilities (air handlers, clean steam, WFI, etc.) for multiple buildings rather than one.