Science

IL-27 Found to Play Significant Role in Conferring HIV Resistance

Portrait of Lue Dai.

Platinum Highlight IconBy Nancy Parrish, Staff Writer

The human immunodeficiency virus (HIV) targets specific immune cells in the body known as macrophages because these are the cells that eliminate foreign material such as bacteria or viruses. HIV is able to reproduce and spread throughout the body if it can avoid destruction by macrophages.

A recent study by Lue Dai, Ph.D., and colleagues revealed that the human cytokine IL-27 helps promote the body’s production of macrophages that are resistant to HIV. The study further found that IL-27 suppresses a gene known as SPTBN1, which facilitates the survival of HIV cells. This breakthrough research was recently published in the Journal of Experimental Medicine.

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$200,000 Grants Awarded to CCR Researchers for HIV/AIDS Studies

Anu Puri and team

By Nancy Parrish, Staff Writer

Earlier this year, the Office of AIDS Research (OAR) awarded two, two-year grants of $200,000 each to Anu Puri, Ph.D., and Robert Blumenthal, Ph.D., both of the Center for Cancer Research (CCR) Nanobiology Program, and to Eric Freed, Ph.D., of the HIV Drug Resistance Program, for their research on potential new treatments for HIV.

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Best Collaborative Publication Announced during Spring Research Festival Week

Two gentlemen having a discussion

By Nancy Parrish, Staff Writer

The winner of the 2012 competition for the best collaborative publication was announced on May 7, as part of the lead-up to the Spring Research Festival sponsored by the National Interagency Confederation for Biological Research (NICBR) and the National Cancer Institute at Frederick on May 8 and 9.

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FNLCR Set to Launch Full-Scale Assault on Ras

Ribbon structure

By Frank Blanchard, Staff Writer

Armed with an array of leading-edge technologies, scientific and technical expertise, and the full backing of the National Cancer Institute’s (NCI’s) scientific advisers, the Frederick National Laboratory for Cancer Research (FNLCR) is preparing to launch a full-scale attack against an intractable problem:  the cancer-causing family of Ras genes.

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