Science

Inaugural Technology Showcase Draws Hundreds

Before a crowded auditorium of science and business professionals at the Frederick National Laboratory for Cancer Research’s Advanced Technology Research Facility, Joost Oppenheim, M.D., had just finished his presentation about a compound with the potential to expand the impact of a promising category of cancer therapeutics when he fielded a question from Stephan Stern, Ph.D. 

Large Cancer Drug Trial Helps Move Precision Medicine Toward the Mainstream

A landmark cancer drug trial is helping set the stage for moving precision medicine into the mainstream of clinical practice, according to a new study. The study, reported in the Journal of Molecular Diagnostics, validates a procedure used in the drug trial that identifies the unique genetic mutations in a patient’s tumor, which is then used as the basis for selecting targeted drugs for treatment.

NCI at Frederick Scientific Library Reintroduces Scientific Publications Database

A 20-year-old database of scientific publications by NCI at Frederick, FNLCR, and affiliated employees has gotten a significant facelift. Maintained by the Scientific Library, the redesigned database—which is linked from each of the Scientific Library’s web pages—offers features that were not available in previous versions, such as additional search limits and non-traditional metrics for scholarly and scientific publishing known as altmetrics.

Yeast Studies Lead to a New DNA-Based Model for Research on Development

A paper from Amar J. S. Klar, Ph.D., with the RNA Biology Laboratory in NCI’s Center for Cancer Research, has identified a model for DNA research that explains the congenital disorder of mirror hand movements in humans. A mirror movement is when an intentional movement on one side of the body is mirrored by an involuntary movement on the other.